Page last updated: 2024-10-26

ethoxyquin and Peripheral Nervous System Diseases

ethoxyquin has been researched along with Peripheral Nervous System Diseases in 2 studies

Ethoxyquin: Antioxidant; also a post-harvest dip to prevent scald on apples and pears.
ethoxyquin : A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.

Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.

Research Excerpts

ExcerptRelevanceReference
" We found that oral bioavailability is about 10%, partly due to rapid metabolism in liver, but EQ-6 appears to be concentrated in neural tissues."1.62Development of EQ-6, a Novel Analogue of Ethoxyquin to Prevent Chemotherapy-Induced Peripheral Neuropathy. ( Alt, J; Brayton, C; Cetinkaya-Fisgin, A; Höke, A; Kim, JS; Luan, X; Oh, B; Rais, R; Slusher, B; Zhu, J, 2021)
"Ethoxyquin was recently identified as a neuroprotective compound against toxic neuropathies and efficacy was demonstrated against paclitaxel-induced neurotoxicity in vivo."1.43Ethoxyquin provides neuroprotection against cisplatin-induced neurotoxicity. ( Carozzi, VA; Cavaletti, G; Hoke, A; Marmiroli, P; Mi, R; Reed, N; Zhu, J, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Cetinkaya-Fisgin, A1
Zhu, J2
Luan, X1
Kim, JS1
Oh, B1
Brayton, C1
Alt, J1
Rais, R1
Slusher, B1
Höke, A2
Carozzi, VA1
Reed, N1
Mi, R1
Marmiroli, P1
Cavaletti, G1

Other Studies

2 other studies available for ethoxyquin and Peripheral Nervous System Diseases

ArticleYear
Development of EQ-6, a Novel Analogue of Ethoxyquin to Prevent Chemotherapy-Induced Peripheral Neuropathy.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:3

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Drug Development; Ethoxyquin; Female; Humans; Male;

2021
Ethoxyquin provides neuroprotection against cisplatin-induced neurotoxicity.
    Scientific reports, 2016, 06-28, Volume: 6

    Topics: Animals; Antineoplastic Agents; Ataxin-2; Axons; Cell Line; Cells, Cultured; Cisplatin; Ethoxyquin;

2016