Page last updated: 2024-10-26

ethoxyquin and Peripheral Nerve Diseases

ethoxyquin has been researched along with Peripheral Nerve Diseases in 2 studies

Ethoxyquin: Antioxidant; also a post-harvest dip to prevent scald on apples and pears.
ethoxyquin : A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.

Research Excerpts

ExcerptRelevanceReference
" We found that oral bioavailability is about 10%, partly due to rapid metabolism in liver, but EQ-6 appears to be concentrated in neural tissues."1.62Development of EQ-6, a Novel Analogue of Ethoxyquin to Prevent Chemotherapy-Induced Peripheral Neuropathy. ( Alt, J; Brayton, C; Cetinkaya-Fisgin, A; Höke, A; Kim, JS; Luan, X; Oh, B; Rais, R; Slusher, B; Zhu, J, 2021)
"Ethoxyquin was recently identified as a neuroprotective compound against toxic neuropathies and efficacy was demonstrated against paclitaxel-induced neurotoxicity in vivo."1.43Ethoxyquin provides neuroprotection against cisplatin-induced neurotoxicity. ( Carozzi, VA; Cavaletti, G; Hoke, A; Marmiroli, P; Mi, R; Reed, N; Zhu, J, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Cetinkaya-Fisgin, A1
Zhu, J2
Luan, X1
Kim, JS1
Oh, B1
Brayton, C1
Alt, J1
Rais, R1
Slusher, B1
Höke, A2
Carozzi, VA1
Reed, N1
Mi, R1
Marmiroli, P1
Cavaletti, G1

Other Studies

2 other studies available for ethoxyquin and Peripheral Nerve Diseases

ArticleYear
Development of EQ-6, a Novel Analogue of Ethoxyquin to Prevent Chemotherapy-Induced Peripheral Neuropathy.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:3

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Drug Development; Ethoxyquin; Female; Humans; Male;

2021
Ethoxyquin provides neuroprotection against cisplatin-induced neurotoxicity.
    Scientific reports, 2016, 06-28, Volume: 6

    Topics: Animals; Antineoplastic Agents; Ataxin-2; Axons; Cell Line; Cells, Cultured; Cisplatin; Ethoxyquin;

2016