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ethoxyquin and Experimental Hepatoma

ethoxyquin has been researched along with Experimental Hepatoma in 11 studies

Ethoxyquin: Antioxidant; also a post-harvest dip to prevent scald on apples and pears.
ethoxyquin : A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.

Research Excerpts

ExcerptRelevanceReference
" Rats were initially given a single ip injection of diethylnitrosamine (200 mg/kg body weight) and fed basal diet containing 0."3.67Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis. ( Inoue, K; Ito, N; Masui, T; Ogiso, T; Tsuda, H, 1986)
" Utilizing the same multiple dosing protocol, patterns of covalent modifications of DNA by AFB1 were determined."1.27Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases. ( Davidson, NE; Egner, PA; Groopman, JD; Kensler, TW; Pikul, A; Roebuck, BD, 1986)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Judah, DJ3
Hayes, JD3
Yang, JC1
Lian, LY1
Roberts, GC1
Farmer, PB1
Lamb, JH1
Neal, GE4
McLeod, R2
Ellis, EM2
Pulford, DJ2
Ireland, LS1
McLellan, LI2
Manson, MM4
James, RF1
SeidegÄrd, J1
Mosialou, E1
Jernström, B1
Shepherd, AG1
Ball, HW1
Tsuda, H2
Ozaki, K1
Uwagawa, S1
Yamaguchi, S1
Hakoi, K1
Aoki, T1
Kato, T1
Sato, K1
Ito, N2
Denda, A1
Ura, H1
Tsujiuchi, T1
Tsutsumi, M1
Eimoto, H1
Takashima, Y1
Kitazawa, S1
Kinugasa, T1
Konishi, Y1
Yeldandi, AV1
Milano, M1
Subbarao, V1
Reddy, JK1
Rao, MS1
Kensler, TW1
Egner, PA1
Davidson, NE1
Roebuck, BD1
Pikul, A1
Groopman, JD1
Green, JA2
Driver, HE1
Mandel, HG1
Simpson, JL1
Forrester, LM1
Wolf, CR1
Masui, T1
Inoue, K1
Ogiso, T1

Reviews

2 reviews available for ethoxyquin and Experimental Hepatoma

ArticleYear
Regulation of glutathione S-transferases and aldehyde reductase by chemoprotectors: studies of mechanisms responsible for inducible resistance to aflatoxin B1.
    IARC scientific publications, 1996, Issue:139

    Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Anticarcinogenic Agents; Biotransformation; Carcinogens;

1996
Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.
    Chemico-biological interactions, 1998, Apr-24, Volume: 111-112

    Topics: Aflatoxin B1; Aldehyde Reductase; Amino Acid Sequence; Animals; Antioxidants; Base Sequence; Biotran

1998

Other Studies

9 other studies available for ethoxyquin and Experimental Hepatoma

ArticleYear
A novel aldehyde reductase with activity towards a metabolite of aflatoxin B1 is expressed in rat liver during carcinogenesis and following the administration of an anti-oxidant.
    The Biochemical journal, 1993, May-15, Volume: 292 ( Pt 1)

    Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Ethoxyquin; Liver; Liver Neoplasms, Experimental; Precanc

1993
Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B(1)-induced preneoplasia.
    Carcinogenesis, 2000, Volume: 21, Issue:10

    Topics: 4-Butyrolactone; Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catalyti

2000
Effects of modifying agents on conformity of enzyme phenotype and proliferative potential in focal preneoplastic and neoplastic liver cell lesions in rats.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:11

    Topics: Adenosine Triphosphatases; Animals; Bromodeoxyuridine; Cell Division; Clofibrate; Diethylhexyl Phtha

1992
Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Biomarkers, Tumor; Body Weight; Diethyl

1989
Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis.
    Cancer letters, 1989, Sep-15, Volume: 47, Issue:1-2

    Topics: Animals; Cell Division; Clofibrate; Clofibric Acid; DNA; Ethoxyquin; Fibric Acids; Liver; Liver Neop

1989
Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Animals; Bile; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; En

1986
Ethoxyquin alone induces preneoplastic changes in rat kidney whilst preventing induction of such lesions in liver by aflatoxin B1.
    Carcinogenesis, 1987, Volume: 8, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antigens, Neoplasm; Body Weight; Carboxylic Ester Hydrolases; End

1987
Metabolic basis for the protective effect of the antioxidant ethoxyquin on aflatoxin B1 hepatocarcinogenesis in the rat.
    Cancer research, 1987, Oct-01, Volume: 47, Issue:19

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cytochrome P-450 Enzyme System; DNA; Ethoxyquin; gamma-Glutamyltr

1987
Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:3

    Topics: 2-Acetylaminofluorene; Acetaminophen; Aniline Compounds; Animals; Body Weight; Butylated Hydroxyanis

1986