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ethosuximide and Tremor

ethosuximide has been researched along with Tremor in 4 studies

Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"Following the demonstration of an anti-tremor effect of ethosuximide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) monkey model, we have tested the effect of this drug in 10 patients with typical parkinsonian tremor."9.07Ethosuximide and tremor in Parkinson's disease: a pilot study. ( Bédard, PJ; Gomez-Mancilla, B; Pourcher, E, 1992)
"Based on the hypothesis that low-threshold calcium conductance in the thalamus might be involved in the pathophysiology of parkinsonian tremor, ethosuximide was given chronically to a monkey previously treated with MPTP and displaying exceptionally a typical rest tremor."7.68Effect of ethosuximide on rest tremor in the MPTP monkey model. ( Bédard, PJ; Boucher, R; Gomez-Mancilla, B; Latulippe, JF, 1992)
"Following the demonstration of an anti-tremor effect of ethosuximide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) monkey model, we have tested the effect of this drug in 10 patients with typical parkinsonian tremor."5.07Ethosuximide and tremor in Parkinson's disease: a pilot study. ( Bédard, PJ; Gomez-Mancilla, B; Pourcher, E, 1992)
" Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate."4.77Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985)
" We measured the effects of a selective blocker of I(T) (ethosuximide) in healthy subjects on the amplitude and frequency of saccadic oscillations evoked by eye closure and of a nonselective blocker of I(h) and I(T) (propronolol) in a patient with microsaccadic oscillation and limb tremor syndrome (mSOLT)."3.77The effects of ion channel blockers validate the conductance-based model of saccadic oscillations. ( Leigh, RJ; Miura, K; Optican, LM; Ramat, S; Shaikh, AG; Zee, DS, 2011)
"Based on the hypothesis that low-threshold calcium conductance in the thalamus might be involved in the pathophysiology of parkinsonian tremor, ethosuximide was given chronically to a monkey previously treated with MPTP and displaying exceptionally a typical rest tremor."3.68Effect of ethosuximide on rest tremor in the MPTP monkey model. ( Bédard, PJ; Boucher, R; Gomez-Mancilla, B; Latulippe, JF, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shaikh, AG1
Zee, DS1
Optican, LM1
Miura, K1
Ramat, S1
Leigh, RJ1
Pourcher, E1
Gomez-Mancilla, B2
Bédard, PJ2
Latulippe, JF1
Boucher, R1
Reynolds, EH1
Trimble, MR1

Reviews

1 review available for ethosuximide and Tremor

ArticleYear
Adverse neuropsychiatric effects of anticonvulsant drugs.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba

1985

Trials

1 trial available for ethosuximide and Tremor

ArticleYear
Ethosuximide and tremor in Parkinson's disease: a pilot study.
    Movement disorders : official journal of the Movement Disorder Society, 1992, Volume: 7, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Ethosuximide; Female; Humans; Male; Middle Aged; Neurologic Exami

1992

Other Studies

2 other studies available for ethosuximide and Tremor

ArticleYear
The effects of ion channel blockers validate the conductance-based model of saccadic oscillations.
    Annals of the New York Academy of Sciences, 2011, Volume: 1233

    Topics: Case-Control Studies; Ethosuximide; Humans; Ion Channels; Models, Biological; Models, Neurological;

2011
Effect of ethosuximide on rest tremor in the MPTP monkey model.
    Movement disorders : official journal of the Movement Disorder Society, 1992, Volume: 7, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Diltiazem; Dopamine Agents; Dose-Response Rel

1992