Page last updated: 2024-10-26

ethosuximide and Substance Withdrawal Syndrome

ethosuximide has been researched along with Substance Withdrawal Syndrome in 7 studies

Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
" Here, we expand on these findings to test whether ethosuximide can reduce the sensitivity to pentylenetetrazole-induced seizures during ethanol withdrawal."3.81Ethosuximide Reduces Mortality and Seizure Severity in Response to Pentylenetetrazole Treatment During Ethanol Withdrawal. ( Godwin, DW; Masicampo, ML; Riegle, MA; Shan, HQ; Xu, V, 2015)
" Dose-response curves for the convulsive effect of pentylenetetrazol obtained at the peak of the withdrawal signs shifted greatly to the left in alcohol withdrawn animals but less in barbital withdrawn animals."1.27Differentiation of alcohol and barbital physical dependence. ( Kaneda, H; Kaneto, H; Kawatani, S, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Riegle, MA1
Masicampo, ML1
Shan, HQ1
Xu, V1
Godwin, DW2
Wiggins, WF1
Graef, JD1
Huitt, TW1
Aminoff, MJ1
Kaneto, H1
Kawatani, S1
Kaneda, H1
Norton, PR1
Hill, RM1
Verniaud, WM1
Horning, MG1
McCulley, LB1
Morgan, NF1

Other Studies

7 other studies available for ethosuximide and Substance Withdrawal Syndrome

ArticleYear
Ethosuximide Reduces Mortality and Seizure Severity in Response to Pentylenetetrazole Treatment During Ethanol Withdrawal.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2015, Volume: 50, Issue:5

    Topics: Alcoholism; Animals; Anticonvulsants; Ethosuximide; Male; Mice; Mice, Inbred DBA; Mortality; Pentyle

2015
Ethosuximide reduces ethanol withdrawal-mediated disruptions in sleep-related EEG patterns.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:3

    Topics: Animals; Brain; Electroencephalography; Ethanol; Ethosuximide; Male; Mice; Mice, Inbred C57BL; Sleep

2013
Drug treatment of epilepsy.
    Comprehensive therapy, 1981, Volume: 7, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female;

1981
Differentiation of alcohol and barbital physical dependence.
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1986, Volume: 6, Issue:2

    Topics: Animals; Barbital; Barbiturates; Diazepam; Ethanol; Ethosuximide; Male; Mice; Morphine; Naloxone; Pe

1986
The effects of drugs on barbiturate withdrawal convulsions in the rat.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:10

    Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Ethanol; Ethosuximide; Female; Humans; Hydr

1970
Anticonvulsant drugs in idiopathic epilepsy.
    The Medical letter on drugs and therapeutics, 1970, Jun-26, Volume: 12, Issue:13

    Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mepho

1970
Infants exposed in utero to antiepileptic drugs. A prospective study.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:5

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chro

1974