ethosuximide has been researched along with Pregnancy in 34 studies
Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A pregnant woman with epilepsy receiving VPA and ethosuximide (ESM) was given high-dose multivitamins from 13 to 28 weeks' gestation." | 3.70 | Valproate-induced biochemical abnormalities in pregnancy corrected by vitamins: a case report. ( Baggot, PJ; Kalamarides, JA; Shoemaker, JD, 1999) |
| " Maternal exposure to imipramine in a dose equivalent to the therapeutic dose per unit body weight induced hyperthermic response to chlorpromazine in the male offspring, while normal control rats showed a marked hypothermia." | 3.69 | Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring. ( Fujii, T, 1997) |
| "Ethosuximide concentration in serum was monitored during the last trimester of pregnancy in a patient." | 3.66 | Ethosuximide pharmacokinetics in a pregnant patient and her newborn. ( Cohen, ME; Koup, JR; Rose, JQ, 1978) |
| "Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies." | 2.35 | Clinical pharmacokinetics of anticonvulsants. ( Dam, M; Hvidberg, EF, 1976) |
| " Pharmacokinetic interactions between antiepileptic drugs may lead to considerable fluctuation in plasma drug concentration, and monotherapy is often preferable." | 1.27 | Pharmacokinetics of antiepileptic drugs. ( Neuvonen, PJ; Tokola, RA, 1983) |
| "Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given." | 1.27 | [Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (79.41) | 18.7374 |
| 1990's | 5 (14.71) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SH | 1 |
| Kang, JW | 1 |
| Lin, T | 1 |
| Lee, JE | 1 |
| Jin, DI | 1 |
| Smyth, MD | 1 |
| Barbaro, NM | 1 |
| Baraban, SC | 1 |
| HEATHFIELD, KW | 1 |
| JEWESBURY, EC | 1 |
| Tokola, RA | 1 |
| Neuvonen, PJ | 1 |
| Schmidt, D | 1 |
| Bruni, J | 1 |
| Albright, PS | 1 |
| Mallow, DW | 1 |
| Herrick, MK | 1 |
| Gathman, G | 1 |
| Kuhnz, W | 1 |
| Koch, S | 1 |
| Jakob, S | 1 |
| Hartmann, A | 1 |
| Helge, H | 1 |
| Nau, H | 1 |
| El-Sayed, MG | 1 |
| Aly, AE | 1 |
| Kadri, M | 1 |
| Moustafa, AM | 1 |
| Morselli, PL | 1 |
| Franco-Morselli, R | 1 |
| Aminoff, MJ | 1 |
| Tomson, T | 1 |
| Villén, T | 1 |
| Ichiba, M | 1 |
| Kitazawa, S | 1 |
| Fujii, T | 2 |
| Baggot, PJ | 1 |
| Kalamarides, JA | 1 |
| Shoemaker, JD | 1 |
| Koup, JR | 1 |
| Rose, JQ | 1 |
| Cohen, ME | 1 |
| Aucamp, AK | 1 |
| Janz, D | 1 |
| Conomy, JP | 1 |
| Reith, H | 1 |
| Schäfer, H | 1 |
| Swanson, PD | 1 |
| Hvidberg, EF | 1 |
| Dam, M | 1 |
| Singer, HS | 1 |
| Freeman, JM | 1 |
| Sullivan, FM | 1 |
| McElhatton, PR | 1 |
| Anderson, RC | 1 |
| Bishun, NP | 1 |
| Smith, NS | 1 |
| Williams, DC | 1 |
| Nakanishi, H | 1 |
| Shinnar, S | 1 |
| Tejerizo López, LC | 1 |
| de Santiago Obeso, J | 1 |
| Henríquez Esquiroz, JM | 1 |
| Pérez González, MC | 1 |
| Jorge Mendoza, JM | 1 |
| Gibberd, FB | 1 |
| Gregoriades, AD | 1 |
| Meyer, JG | 1 |
| Wagner, JG | 1 |
| Hill, RM | 1 |
| Verniaud, WM | 1 |
| Horning, MG | 1 |
| McCulley, LB | 1 |
| Morgan, NF | 1 |
8 reviews available for ethosuximide and Pregnancy
| Article | Year |
|---|---|
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; H | 1980 |
[Ethosuximide].
Topics: Adult; Anticonvulsants; Child; Drug Monitoring; Ethosuximide; Female; Humans; Infant, Newborn; Metho | 1995 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
The teratogenic risk of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anencephaly; Anti-Anxiety Agents; Anticonvulsa | 1975 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; | 1979 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam | 1976 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Dru | 1987 |
26 other studies available for ethosuximide and Pregnancy
| Article | Year |
|---|---|
Teratogenic potential of antiepileptic drugs in the zebrafish model.
Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Ethosuximide; Female; F | 2013 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disea | 2002 |
TREATMENT OF PETIT MAL WITH ETHOSUXIMIDE: FOLLOW-UP REPORT.
Topics: Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Pregn | 1964 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, | 1983 |
Fetal exposure to anticonvulsant drugs. Detailed pathological study of a case.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Adult; Anticonvulsants; Brain; Cardiomegaly; Epilepsy; E | 1980 |
Ethosuximide in epileptic women during pregnancy and lactation period. Placental transfer, serum concentrations in nursed infants and clinical status.
Topics: Abnormalities, Drug-Induced; Epilepsy; Ethosuximide; Female; Humans; Infant, Newborn; Lactation; Mal | 1984 |
Comparative study on the teratogenicity of some antiepileptics in the rat.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Carbamazepine; Ethos | 1983 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; | 1981 |
Ethosuximide enantiomers in pregnancy and lactation.
Topics: Adult; Chromatography, Gas; Drug Monitoring; Epilepsy; Ethosuximide; Female; Humans; Isomerism; Lact | 1994 |
Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring.
Topics: Aggression; Aminobutyrates; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplast | 1997 |
Valproate-induced biochemical abnormalities in pregnancy corrected by vitamins: a case report.
Topics: Adult; Anticonvulsants; Epilepsy; Ethosuximide; Female; Humans; Metabolic Diseases; Pantothenic Acid | 1999 |
Ethosuximide pharmacokinetics in a pregnant patient and her newborn.
Topics: Adult; Dose-Response Relationship, Drug; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Fe | 1978 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximi | 1978 |
Anticonvulsant therapy. Approaches to some common clinical problems.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Eth | 1979 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differen | 1975 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Fema | 1977 |
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadio | 1976 |
Chromosomes and anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cells, Cultured; Chromatids; Chromosome Aberrations; C | 1975 |
Behavioral changes in juvenile rats after prenatal exposure to ethosuximide.
Topics: Animals; Ethosuximide; Female; Interpersonal Relations; Male; Motor Activity; Pregnancy; Prenatal Ex | 1990 |
[Metabolism and elimination of ethosuximide in neonates whose mothers had petit mal].
Topics: Epilepsy, Absence; Ethosuximide; Female; Half-Life; Humans; Infant, Newborn; Pregnancy; Pregnancy Co | 1987 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, T | 1969 |
A medical and social survey of 231 children with seizures.
Topics: Adolescent; Attitude to Health; Child; Child Behavior Disorders; Child, Preschool; Electroencephalog | 1972 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohe | 1973 |
Intrasubject variation in elimination half-lives of drugs which are appreciably metabolized.
Topics: Adult; Analysis of Variance; Capsules; Child; Chlorides; Chromatography, Thin Layer; Clindamycin; Do | 1973 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chro | 1974 |