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ethosuximide and Libman-Sacks Disease

ethosuximide has been researched along with Libman-Sacks Disease in 22 studies

Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

Research Excerpts

ExcerptRelevanceReference
"A 15-year-old boy with epilepsy and cerebral calcifications, treated with valproic acid, ethyl phenylbarbiturate and ethosuximide, was referred for drug induced systemic lupus erythematosus."7.71Latent coeliac disease in a child with epilepsy, cerebral calcifications, drug-induced systemic lupus erythematosus and intestinal folic acid malabsorption associated with impairment of folic acid transport across the blood-brain barrier. ( Calvani, M; Guaitolini, C; Paolone, G; Parisi, G; Parisi, P, 2001)
"A 15-year-old boy with epilepsy and cerebral calcifications, treated with valproic acid, ethyl phenylbarbiturate and ethosuximide, was referred for drug induced systemic lupus erythematosus."3.71Latent coeliac disease in a child with epilepsy, cerebral calcifications, drug-induced systemic lupus erythematosus and intestinal folic acid malabsorption associated with impairment of folic acid transport across the blood-brain barrier. ( Calvani, M; Guaitolini, C; Paolone, G; Parisi, G; Parisi, P, 2001)
" Following treatment with antiepileptic drugs (AEDs), the patient developed several rare complications: after beginning therapy with phenytoin, the patient developed pseudolymphoma; after monotherapy with carbamazepine (CBZ), the patient thereafter developed myoclonic jerks of upper and lower limbs upon awakening; after one year of treatment with valproate (VPA) the patient developed clinical and immuno-haematological signs of SLE."3.69Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. ( Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G, 1996)
"Drug-induced systemic lupus erythematosus (SLE)-like syndromes in children are most commonly associated with the administration of ethosuximide, diphenylhydantoin, and trimethadione."1.26Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants. ( Fishman, L; Hanson, V; Singsen, BH, 1976)
"Features of both systemic lupus erythematosus and scleroderma developed in a young Chinese girl while on multiple anticonvulsant therapy."1.25Lupus-scleroderma syndrome induced by ethosuximide. ( Chan, HL; Teoh, PC, 1975)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199012 (54.55)18.7374
1990's5 (22.73)18.2507
2000's2 (9.09)29.6817
2010's1 (4.55)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Sanghavi, R1
Sukumaran, S1
Hashkes, PJ1
Toyama, T1
Asano, Y1
Taniguchi, T1
Takahashi, T1
Ichimura, Y1
Tamaki, Z1
Kagami, S1
Mitsui, H1
Sato, S1
Crespel, A1
Velizarova, R1
Agullo, M1
Gélisse, P1
Koike, K1
Naganuma, K1
Ishii, E1
Tsuji, K1
Ando, O1
Yagi, Y1
Norose, N1
Saitoh, H1
Nakahata, T1
Komiyama, A1
Ansell, BM1
Miyasaka, N1
Takeda, S1
Koizumi, F1
Takazakura, E1
Gigli, GL1
Scalise, A1
Silvestri, G1
Diomedi, M1
Placidi, F1
Pomponi, MG1
Masala, C1
Casteels, K1
Van Geet, C1
Wouters, K1
Calvani, M1
Parisi, P1
Guaitolini, C1
Parisi, G1
Paolone, G1
Tor, J1
Rey, C1
Fernández-Sevilla, T1
Martí Vilalta, JL1
Teoh, PC1
Chan, HL1
Singsen, BH1
Fishman, L1
Hanson, V1
Lovisetto, P1
Mairano, D1
Cargnino, M1
Biarese, V1
Marchi, L1
Lerda, R1
Almeyda, J1
Levantine, A1
Beernink, DH1
Miller, JJ1
Dormont, J1
Sobel, A1
Galanaud, P1
Boelaert, J1
Mery, JP1
Richet, G1
Livingston, S1
Rodriguez, H1
Greene, CA1
Pauli, LL1
Dabbous, IA1
Idriss, HM1
Alter, BP1
Monnet, P1
Salle, B1
Poncet, J1
Gauthier, J1
Philoppe, N1
Germain, D1

Reviews

2 reviews available for ethosuximide and Libman-Sacks Disease

ArticleYear
Drug-induced lupus.
    Internal medicine (Tokyo, Japan), 1996, Volume: 35, Issue:7

    Topics: Antibodies, Antinuclear; Anticonvulsants; Ethosuximide; Female; Humans; Hydralazine; Lupus Erythemat

1996
Drug reactions. XX. Cutaneous reactions to anticonvulsants.
    The British journal of dermatology, 1972, Volume: 87, Issue:6

    Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dermatitis, Ex

1972

Other Studies

20 other studies available for ethosuximide and Libman-Sacks Disease

ArticleYear
Drug-Induced Lupus in Association With Ethosuximide Therapy in an 11-Year-Old Child.
    Pediatric neurology, 2023, Volume: 143

    Topics: Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lupus Erythematosus, Systemic

2023
50 Years Ago in TheJournal ofPediatrics: Occurrence of Systemic Lupus Erythematosus in Association with Ethosuccimide Therapy.
    The Journal of pediatrics, 2020, Volume: 219

    Topics: Anticonvulsants; Child; Ethosuximide; Humans; Lupus Erythematosus, Systemic; Male

2020
Ethosuximide-induced lupus-scleroderma syndrome with disease-specific autoantibodies.
    European journal of dermatology : EJD, 2017, 04-01, Volume: 27, Issue:2

    Topics: Anticonvulsants; Autoantibodies; Child; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic;

2017
Ethosuximide-induced de novo systemic lupus erythematosus with anti-double-strand DNA antibodies: a case report with definite evidence.
    Epilepsia, 2009, Volume: 50, Issue:8

    Topics: Antibodies, Antinuclear; Anticonvulsants; Epilepsy, Absence; Ethosuximide; Female; Humans; Lupus Ery

2009
[Drug-induced pancytopenia and systemic lupus erythematosus. Immune suppression of hemopoietic progenitor cells in the presence of the patient's peripheral blood cells, acute serum and the drug].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1984, Volume: 25, Issue:10

    Topics: Autoimmune Diseases; Cells, Cultured; Child; Colony-Forming Units Assay; Ethosuximide; Female; Hemat

1984
Drug-induced systemic lupus erythematosus in a nine-year-old boy.
    Lupus, 1993, Volume: 2, Issue:3

    Topics: Adrenal Cortex Hormones; Child; Ethosuximide; Humans; Lupus Erythematosus, Systemic; Male

1993
Ethosuximide-induced lupus-like syndrome with renal involvement.
    Internal medicine (Tokyo, Japan), 1996, Volume: 35, Issue:7

    Topics: Adult; Anticonvulsants; Arterioles; Ethosuximide; Humans; Kidney Glomerulus; Lupus Erythematosus, Sy

1996
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
    The International journal of neuroscience, 1996, Volume: 87, Issue:3-4

    Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromoso

1996
Ethosuximide-associated lupus with cerebral and renal manifestations.
    European journal of pediatrics, 1998, Volume: 157, Issue:9

    Topics: Anticonvulsants; Brain Diseases; Child; Epilepsy, Absence; Ethosuximide; Female; Humans; Kidney Dise

1998
Latent coeliac disease in a child with epilepsy, cerebral calcifications, drug-induced systemic lupus erythematosus and intestinal folic acid malabsorption associated with impairment of folic acid transport across the blood-brain barrier.
    European journal of pediatrics, 2001, Volume: 160, Issue:5

    Topics: Adolescent; Anticonvulsants; Biological Transport; Blood-Brain Barrier; Brain; Brain Diseases; Calci

2001
[Systemic lupus erythematosus induced by anticonvulsivant drug (author's transl)].
    Medicina clinica, 1979, Dec-15, Volume: 73, Issue:10

    Topics: Adult; Antibodies, Antinuclear; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide;

1979
Lupus-scleroderma syndrome induced by ethosuximide.
    Archives of disease in childhood, 1975, Volume: 50, Issue:8

    Topics: Adolescent; Anemia; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Lupus Erythematosus, Syste

1975
Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants.
    Pediatrics, 1976, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Antibodies, Antinuclear; Anticonvulsants; Child; Child, Preschool; Ethosuximide;

1976
[A case of drug-induced lupus].
    Recenti progressi in medicina, 1985, Volume: 76, Issue:2

    Topics: Adult; Anticonvulsants; Carbamazepine; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic;

1985
Anticonvulsant-induced antinuclear antibodies and lupus-like disease in children.
    The Journal of pediatrics, 1973, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Age Factors; Antibodies, Antinuclear; Antibody Formation; Anticonvulsants; Child;

1973
[Exploration of cellular immunity during systemic lupus erythematosus].
    Journal d'urologie et de nephrologie, 1972, Volume: 78, Issue:12

    Topics: Cell Migration Inhibition; DNA; Ethosuximide; Female; Glomerulonephritis; Humans; Immunity, Cellular

1972
Systemic lupus erythematosus. Occurrence in association with ethosuximide therapy.
    JAMA, 1968, May-20, Volume: 204, Issue:8

    Topics: Child, Preschool; Epilepsy, Absence; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic

1968
Occurrence of systemic lupus erythematosus in association with ethosuccimide therapy. Case report.
    The Journal of pediatrics, 1970, Volume: 76, Issue:4

    Topics: Child; Epilepsy, Absence; Ethosuximide; Humans; Lupus Erythematosus, Systemic; Male

1970
Systemic lupus erythematosus and ethosuccimide.
    The Journal of pediatrics, 1970, Volume: 77, Issue:6

    Topics: Child; Epilepsy; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic

1970
[Disseminated lupus erythematosis induced by ethosuximeide in a 6-year-old girl].
    Lyon medical, 1968, Sep-15, Volume: 220, Issue:37

    Topics: Child; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic; Seizures

1968