Page last updated: 2024-10-26

ethosuximide and Learning Disabilities

ethosuximide has been researched along with Learning Disabilities in 5 studies

Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.

Research Excerpts

ExcerptRelevanceReference
" To test the effect of antiepileptic drugs on kindled seizures and kindling-induced learning deficits we injected ethosuximide, dipropylacetate, and phenobarbital prior to each kindling stimulation or after kindling completion, and tested these animals in a shuttle-box paradigm."3.69Antiepileptic drugs--their effects on kindled seizures and kindling-induced learning impairments. ( Becker, A; Brosz, M; Grecksch, G, 1995)
" However, dose-response studies showed that lower doses of CGP35348 that failed to influence atypical absence seizure activity, completely reversed the spatial working memory deficit."1.33GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures. ( Burnham, WM; Chan, KF; Cortez, MA; Jia, Z; Snead, OC, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, KF1
Burnham, WM1
Jia, Z1
Cortez, MA1
Snead, OC1
Becker, A1
Grecksch, G1
Brosz, M1
Stores, G1
Smith, WL2
Philippus, MJ1
Guard, HL1
Weyl, TC1

Reviews

1 review available for ethosuximide and Learning Disabilities

ArticleYear
Behavioural effects of anti-epileptic drugs.
    Developmental medicine and child neurology, 1975, Volume: 17, Issue:5

    Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excess

1975

Trials

1 trial available for ethosuximide and Learning Disabilities

ArticleYear
Psychometric study of children with learning problems and 14-6 positive spike EEG patterns, treated with ethosuximide (Zarontin) and placebo.
    Archives of disease in childhood, 1968, Volume: 43, Issue:231

    Topics: Adolescent; Child; Child Behavior Disorders; Clinical Trials as Topic; Electroencephalography; Ethos

1968

Other Studies

3 other studies available for ethosuximide and Learning Disabilities

ArticleYear
GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures.
    European journal of pharmacology, 2006, Jul-10, Volume: 541, Issue:1-2

    Topics: Animals; Anticholesteremic Agents; Anticonvulsants; Chronic Disease; Disease Models, Animal; Dose-Re

2006
Antiepileptic drugs--their effects on kindled seizures and kindling-induced learning impairments.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3

    Topics: Animals; Anticonvulsants; Avoidance Learning; Cognition; Dose-Response Relationship, Drug; Ethosuxim

1995
The effects of ethosuximide (zarontin) on intellectual functions of children with learning deficits and cortical brain dysfunction.
    Current therapeutic research, clinical and experimental, 1968, Volume: 10, Issue:6

    Topics: Adolescent; Analysis of Variance; Brain Damage, Chronic; Child; Electroencephalography; Ethosuximide

1968