ethosuximide has been researched along with Intellectual Disability in 5 studies
Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following treatment with antiepileptic drugs (AEDs), the patient developed several rare complications: after beginning therapy with phenytoin, the patient developed pseudolymphoma; after monotherapy with carbamazepine (CBZ), the patient thereafter developed myoclonic jerks of upper and lower limbs upon awakening; after one year of treatment with valproate (VPA) the patient developed clinical and immuno-haematological signs of SLE." | 3.69 | Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. ( Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G, 1996) |
| "The case of a mentally handicapped female patient is presented who developed typical pellagra with dermatitis, diarrhoea and mental alteration following a long-term antiepileptic treatment with phenytoin, ethosuximide and valproic acid." | 3.68 | [Pellagra in anticonvulsive therapy]. ( Bartels, H; Hebestreit, H; Mingers, AM; Pannenbecker, J, 1990) |
| "This article describes a girl with mental retardation, probably due to a perinatal complication, who had typical absence seizures with characteristic electroencephalographic findings of childhood absence epilepsy, including normal background activity." | 1.35 | Childhood absence epilepsy with clinically apparent genetic and acquired burdens: a diagnostic consideration. ( Wakamoto, H, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wakamoto, H | 1 |
| Bower, BD | 1 |
| Jeavons, PM | 1 |
| Gigli, GL | 1 |
| Scalise, A | 1 |
| Silvestri, G | 1 |
| Diomedi, M | 1 |
| Placidi, F | 1 |
| Pomponi, MG | 1 |
| Masala, C | 1 |
| Hebestreit, H | 1 |
| Pannenbecker, J | 1 |
| Mingers, AM | 1 |
| Bartels, H | 1 |
| Houben, PF | 1 |
| Hommes, OR | 1 |
| Knaven, PJ | 1 |
5 other studies available for ethosuximide and Intellectual Disability
| Article | Year |
|---|---|
Childhood absence epilepsy with clinically apparent genetic and acquired burdens: a diagnostic consideration.
Topics: Action Potentials; Anticonvulsants; Birth Injuries; Brain; Causality; Child; Child, Preschool; Comor | 2008 |
The "happy puppet" syndrome.
Topics: Child; Chlordiazepoxide; Electroencephalography; Epilepsy; Ethosuximide; Eye Diseases; Facial Expres | 1967 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromoso | 1996 |
[Pellagra in anticonvulsive therapy].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Intellect | 1990 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Human | 1971 |