Page last updated: 2024-10-26

ethosuximide and Folic Acid Deficiency

ethosuximide has been researched along with Folic Acid Deficiency in 4 studies

Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

Research Excerpts

ExcerptRelevanceReference
" Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate."4.77Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reynolds, EH3
Trimble, MR2
Gibberd, FB1

Reviews

2 reviews available for ethosuximide and Folic Acid Deficiency

ArticleYear
Mental effects of antiepileptic medication: a review.
    Epilepsia, 1983, Volume: 24 Suppl 2

    Topics: Adolescent; Adult; Anticonvulsants; Attention; Barbiturates; Brain Chemistry; Carbamazepine; Child;

1983
Adverse neuropsychiatric effects of anticonvulsant drugs.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba

1985

Other Studies

2 other studies available for ethosuximide and Folic Acid Deficiency

ArticleYear
Anticonvulsant drugs and mental symptoms: a review.
    Psychological medicine, 1976, Volume: 6, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Folic Acid

1976
Epilepsy.
    British medical journal, 1969, Nov-01, Volume: 4, Issue:5678

    Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, T

1969