ethosuximide has been researched along with Epilepsies, Partial in 21 studies
Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The point estimates of carbamazepine and lamotrigine efficacy showed their superiority with respect to all comparator antiepileptic drugs for the treatment of newly diagnosed focal epilepsy." | 4.98 | Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis. ( Crescioli, G; De Masi, S; Guerrini, R; Ilvento, L; Lucenteforte, E; McGreevy, KS; Mugelli, A; Pugi, A; Rosati, A; Virgili, G, 2018) |
| "Carbamazepine was administered to eight patients, none of whom improved." | 2.69 | Dramatic effect of ethosuximide on epileptic negative myoclonus: implications for the neurophysiological mechanism. ( Hara, M; Oguni, H; Osawa, M; Sunahara, M; Tanaka, T; Uehara, T, 1998) |
| "Atypical benign partial epilepsy (ABPE) is characterized by centro-temporal electroencephalography (EEG) spikes, continuous spike and waves during sleep (CSWS), and multiple seizure types including epileptic negative myoclonus (ENM), but not tonic seizures." | 1.40 | Magnetoencephalography localizing spike sources of atypical benign partial epilepsy. ( Chan, D; Haginoya, K; Kaneko, Y; Nakagawa, E; Nakasato, N; Otsubo, H; Saitoh, S; Shiraishi, H, 2014) |
| "Epileptic negative myoclonus disappeared in all patients 15 to 30 days after ethosuximide was started." | 1.30 | Ethosuximide is effective in the treatment of epileptic negative myoclonus in childhood partial epilepsy. ( Beccaria, F; Capovilla, G; Meletti, S; Rubboli, G; Tassinari, CA; Veggiotti, P, 1999) |
| "Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given." | 1.27 | [Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (52.38) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosati, A | 1 |
| Ilvento, L | 1 |
| Lucenteforte, E | 1 |
| Pugi, A | 1 |
| Crescioli, G | 1 |
| McGreevy, KS | 1 |
| Virgili, G | 1 |
| Mugelli, A | 1 |
| De Masi, S | 1 |
| Guerrini, R | 1 |
| Lagae, L | 1 |
| Baulac, S | 1 |
| Ishida, S | 1 |
| Mashimo, T | 1 |
| Boillot, M | 1 |
| Fumoto, N | 1 |
| Kuwamura, M | 1 |
| Ohno, Y | 1 |
| Takizawa, A | 1 |
| Aoto, T | 1 |
| Ueda, M | 1 |
| Ikeda, A | 1 |
| LeGuern, E | 1 |
| Takahashi, R | 1 |
| Serikawa, T | 1 |
| Ermolenko, NA | 1 |
| Ermakov, AIu | 1 |
| Buchneva, IA | 1 |
| Voronkova, KV | 1 |
| Zakharova, EI | 1 |
| Shiraishi, H | 1 |
| Haginoya, K | 1 |
| Nakagawa, E | 1 |
| Saitoh, S | 1 |
| Kaneko, Y | 1 |
| Nakasato, N | 1 |
| Chan, D | 1 |
| Otsubo, H | 1 |
| Gilbert, TH | 2 |
| Corley, SM | 1 |
| Teskey, GC | 2 |
| Kubota, M | 1 |
| Nakura, M | 1 |
| Hirose, H | 1 |
| Kimura, I | 1 |
| Sakakihara, Y | 1 |
| Rowan, AJ | 1 |
| Berendes, K | 1 |
| Mattes, W | 1 |
| Dörstelmann, D | 1 |
| Schmidt, D | 1 |
| Davies, SM | 1 |
| Oguni, H | 1 |
| Uehara, T | 1 |
| Tanaka, T | 1 |
| Sunahara, M | 1 |
| Hara, M | 1 |
| Osawa, M | 1 |
| Capovilla, G | 1 |
| Beccaria, F | 1 |
| Veggiotti, P | 1 |
| Rubboli, G | 1 |
| Meletti, S | 1 |
| Tassinari, CA | 1 |
| Gibberd, FB | 2 |
| Wallace, SJ | 1 |
| Favel, P | 1 |
| Cartier, J | 1 |
| Gratadou, JP | 1 |
| Gratadou, G | 1 |
| Engel, E | 1 |
| Böhl, I | 1 |
| Schulz, H | 1 |
| Kutt, H | 1 |
| Louis, S | 1 |
| Degen, R | 1 |
3 reviews available for ethosuximide and Epilepsies, Partial
| Article | Year |
|---|---|
Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Ch | 2018 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; E | 1983 |
Use of ethosuximide and valproate in the treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Brain Diseases; Drug Interactions; Epilepsies, Myoclonic; Epilepsies, P | 1986 |
1 trial available for ethosuximide and Epilepsies, Partial
| Article | Year |
|---|---|
Dramatic effect of ethosuximide on epileptic negative myoclonus: implications for the neurophysiological mechanism.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Child, Preschool; Electro | 1998 |
17 other studies available for ethosuximide and Epilepsies, Partial
| Article | Year |
|---|---|
Rational treatment options with AEDs and ketogenic diet in Landau-Kleffner syndrome: still waiting after all these years.
Topics: Anticonvulsants; Behavior Therapy; Benzodiazepines; Child; Combined Modality Therapy; Diet, Ketogeni | 2009 |
A rat model for LGI1-related epilepsies.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Brain; Carbamazepine; Cells, Cultured; Chlorocebus ae | 2012 |
[Idiopathic focal epilepsies of infancy and childhood].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; El | 2011 |
Magnetoencephalography localizing spike sources of atypical benign partial epilepsy.
Topics: Adolescent; Anticonvulsants; Brain; Brain Mapping; Brain Waves; Child; Child, Preschool; Cognition D | 2014 |
Conventional anticonvulsant drugs in the guinea pig kindling model of partial seizures: effects of acute phenobarbital, valproate, and ethosuximide.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsies, Part | 2002 |
A magnetoencephalographic study of negative myoclonus in a patient with atypical benign partial epilepsy.
Topics: Anticonvulsants; Child; Dominance, Cerebral; Electroencephalography; Epilepsies, Myoclonic; Epilepsi | 2005 |
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; | 2007 |
[Drug treatment of reading epilepsy].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Etho | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, | 1983 |
Epilepsy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalogr | 1984 |
Ethosuximide is effective in the treatment of epileptic negative myoclonus in childhood partial epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalogra | 1999 |
Diseases of the central nervous system: Epilepsy.
Topics: Age Factors; Diazepam; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Eth | 1975 |
Depamide in the treatment of epilepsy. A clinical trial.
Topics: Adolescent; Adult; Amides; Anticonvulsants; Barbiturates; Child; Child, Preschool; Electroencephalog | 1973 |
[Outpatient therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Depression, Chemical; Drug Eruptions; Drug Hypersensitivity; Epilepsi | 1970 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, T | 1969 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalog | 1972 |
[Experiences with suxilep in childhood epilepsy].
Topics: Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; E | 1969 |