ethosuximide has been researched along with Epilepsies, Myoclonic in 20 studies
Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Epilepsies, Myoclonic: A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on a 3-year-old boy with myoclonic-astatic epilepsy who developed myoclonic status epilepticus with continuous twitching of the face and unresponsiveness under monotherapy with levetiracetam." | 7.73 | Levetiracetam-induced myoclonic status epilepticus in myoclonic-astatic epilepsy: a case report. ( Krämer, G; Kröll-Seger, J; Mothersill, IW; Novak, S; Sälke-Kellermann, RA, 2006) |
| " The aim of this study was to evaluate the profile of interactions between FBM and four conventional antiepileptic drugs (AEDs): clonazepam (CZP), ethosuximide (ESM), phenobarbital (PB), and valproate (VPA), in pentylenetetrazole (PTZ)-induced convulsions in mice, a model of myoclonic seizures in humans." | 7.72 | Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice. ( Borowicz, KK; Czuczwar, SJ; Luszczki, JJ, 2004) |
| "The action of ethosuximide (125 or 250 mg/kg, IP) against picrotoxin-induced seizures (3-6 mg/kg, IP) was assessed in rats 12, 18, 25, and 90 days old." | 7.68 | Ethosuximide suppresses seizures and lethality induced by picrotoxin in developing rats. ( Mares, P; Micianiková, D; Rokyta, R; Velísek, L; Velísková, J, 1993) |
| "Valproic acid, a new anticonvulsant, is most effective in absence seizures (simple and complex), but it has produced improvement in tonicclonic seizures, mixed absence with tonic-clonic seizures, and myoclonic epilepsy." | 5.04 | Valproic acid (Depakene). A new anticonvulsant agent. ( Lewis, JR, 1978) |
| "We report on a 3-year-old boy with myoclonic-astatic epilepsy who developed myoclonic status epilepticus with continuous twitching of the face and unresponsiveness under monotherapy with levetiracetam." | 3.73 | Levetiracetam-induced myoclonic status epilepticus in myoclonic-astatic epilepsy: a case report. ( Krämer, G; Kröll-Seger, J; Mothersill, IW; Novak, S; Sälke-Kellermann, RA, 2006) |
| " The aim of this study was to evaluate the profile of interactions between FBM and four conventional antiepileptic drugs (AEDs): clonazepam (CZP), ethosuximide (ESM), phenobarbital (PB), and valproate (VPA), in pentylenetetrazole (PTZ)-induced convulsions in mice, a model of myoclonic seizures in humans." | 3.72 | Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice. ( Borowicz, KK; Czuczwar, SJ; Luszczki, JJ, 2004) |
| "The interaction of 7-nitroindazole (7-NI), a nitric oxide synthase (NOS) inhibitor, with the protective activity of conventional antiepileptics against pentylenetetrazol (PTZ)-induced seizures was tested in mice." | 3.70 | 7-Nitroindazole, a nitric oxide synthase inhibitor, enhances the anticonvulsive action of ethosuximide and clonazepam against pentylenetetrazol-induced convulsions. ( Borowicz, KK; Czuczwar, SJ; Kleinrok, Z; Luszczki, J, 2000) |
| "The action of ethosuximide (125 or 250 mg/kg, IP) against picrotoxin-induced seizures (3-6 mg/kg, IP) was assessed in rats 12, 18, 25, and 90 days old." | 3.68 | Ethosuximide suppresses seizures and lethality induced by picrotoxin in developing rats. ( Mares, P; Micianiková, D; Rokyta, R; Velísek, L; Velísková, J, 1993) |
| "Severe myoclonic epilepsy of infants usually worsens with lamotrigine, but occasionally, children improve." | 2.40 | Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide. ( Wallace, SJ, 1998) |
| "Benign myoclonic epilepsy in infancy (BMEI) is the youngest form of idiopathic generalized epilepsy, characterized by myoclonic seizures (MS) in the first three years of life in otherwise normal infants, and the lack of other seizure types except for rare simple febrile seizures." | 1.38 | Benign myoclonic epilepsy in infancy with preceding afebrile generalized tonic-clonic seizures in Japan. ( Ito, S; Oguni, H; Osawa, M, 2012) |
| "An 11-year-old boy with intractable myoclonic epilepsy and severe psychomotor delay experienced FN during medication of ethosuximide." | 1.31 | Forced normalization induced by ethosuximide therapy in a patient with intractable myoclonic epilepsy. ( Akaboshi, S; Narai, S; Pipo, JR; Yamamoto, T, 2001) |
| "Twelve patients with benign juvenile myoclonic epilepsy (BJME) representing 4% of our population of epileptics (n = 275) are presented." | 1.27 | Some clinical and EEG aspects of benign juvenile myoclonic epilepsy. ( Asconapé, J; Penry, JK, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (25.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Popławska, M | 1 |
| Wróblewska, D | 1 |
| Borowicz, KK | 4 |
| Ito, S | 1 |
| Oguni, H | 2 |
| Osawa, M | 1 |
| Piskorska, B | 1 |
| Stępniak, B | 1 |
| Czuczwar, SJ | 3 |
| Haugvicová, R | 1 |
| Bílková, E | 1 |
| Kubová, H | 1 |
| Mares, P | 2 |
| Luszczki, JJ | 1 |
| Kubota, M | 1 |
| Nakura, M | 1 |
| Hirose, H | 1 |
| Kimura, I | 1 |
| Sakakihara, Y | 1 |
| Aujard, Y | 1 |
| Ponsot, G | 1 |
| Livet, MO | 1 |
| Kröll-Seger, J | 1 |
| Mothersill, IW | 1 |
| Novak, S | 1 |
| Sälke-Kellermann, RA | 1 |
| Krämer, G | 1 |
| Kilaru, S | 1 |
| Bergqvist, AGC | 1 |
| Asconapé, J | 1 |
| Penry, JK | 1 |
| Velísková, J | 1 |
| Velísek, L | 1 |
| Rokyta, R | 1 |
| Micianiková, D | 1 |
| Wallace, SJ | 2 |
| Luszczki, J | 1 |
| Kleinrok, Z | 1 |
| Capovilla, G | 1 |
| Rubboli, G | 1 |
| Beccaria, F | 1 |
| Meregalli, S | 1 |
| Veggiotti, P | 1 |
| Giambelli, PM | 1 |
| Meletti, S | 1 |
| Tassinari, CA | 1 |
| Yamamoto, T | 1 |
| Pipo, JR | 1 |
| Akaboshi, S | 1 |
| Narai, S | 1 |
| Lewis, JR | 1 |
| Aucamp, AK | 1 |
| Todt, H | 1 |
| Müller, D | 1 |
4 reviews available for ethosuximide and Epilepsies, Myoclonic
| Article | Year |
|---|---|
[Epilepsy with myoclonic absences].
Topics: Child; Child, Preschool; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; | 2002 |
Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Ethosuximide; Humans; Infant; Isoxa | 1998 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
Use of ethosuximide and valproate in the treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Brain Diseases; Drug Interactions; Epilepsies, Myoclonic; Epilepsies, P | 1986 |
2 trials available for ethosuximide and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Effects of fluoxetine on the anticonvulsant action of valproate and ethosuximide in mouse model of myoclonic convulsions.
Topics: Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Avoidance Learning; Convulsants; | 2012 |
Valproic acid (Depakene). A new anticonvulsant agent.
Topics: Animals; Child; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Epilepsies, Myoclonic; | 1978 |
14 other studies available for ethosuximide and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Interactions between an antidepressant reboxetine and four classic antiepileptic drugs in the mouse model of myoclonic seizures.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Avoidance Learning; Clonazepam; Disease Models, Ani | 2015 |
Benign myoclonic epilepsy in infancy with preceding afebrile generalized tonic-clonic seizures in Japan.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Clonazepam; Electroenceph | 2012 |
Effects of classical antiepileptics on thresholds for phenomena induced by cortical stimulation in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation; Electroencephalography; Elec | 2002 |
Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonazepam; Disease Models, Animal; Drug Interactions; D | 2004 |
A magnetoencephalographic study of negative myoclonus in a patient with atypical benign partial epilepsy.
Topics: Anticonvulsants; Child; Dominance, Cerebral; Electroencephalography; Epilepsies, Myoclonic; Epilepsi | 2005 |
[Rickets. A rare complication of anti-epileptic treatments. Report of two cases in children].
Topics: Anticonvulsants; Black People; Calcifediol; Child; Contraindications; Drug Monitoring; Electroenceph | 1976 |
Levetiracetam-induced myoclonic status epilepticus in myoclonic-astatic epilepsy: a case report.
Topics: Anticonvulsants; Behavior; Child, Preschool; Electroencephalography; Electromyography; Epilepsies, M | 2006 |
Current treatment of myoclonic astatic epilepsy: clinical experience at the Children's Hospital of Philadelphia.
Topics: Age of Onset; Anticonvulsants; Child; Cognition Disorders; Dietary Fats; Electroencephalography; Epi | 2007 |
Some clinical and EEG aspects of benign juvenile myoclonic epilepsy.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Combinations; Electroencephalography; Epile | 1984 |
Ethosuximide suppresses seizures and lethality induced by picrotoxin in developing rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Ethosuxim | 1993 |
7-Nitroindazole, a nitric oxide synthase inhibitor, enhances the anticonvulsive action of ethosuximide and clonazepam against pentylenetetrazol-induced convulsions.
Topics: Animals; Anticonvulsants; Avoidance Learning; Clonazepam; Disease Models, Animal; Drug Interactions; | 2000 |
Intermittent falls and fecal incontinence as a manifestation of epileptic negative myoclonus in idiopathic partial epilepsy of childhood.
Topics: Accidental Falls; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsies, Myoc | 2000 |
Forced normalization induced by ethosuximide therapy in a patient with intractable myoclonic epilepsy.
Topics: Anticonvulsants; Cerebral Cortex; Child; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide | 2001 |
The therapy of benign myoclonic epilepsy in infants.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencep | 1992 |