ethosuximide has been researched along with Convulsive Generalized Seizure Disorder in 9 studies
Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrathecal administration of antiseizure drugs (ASDs) e." | 5.72 | Intrathecal application of ethosuximide is highly efficient in suppressing seizures in a genetic model of absence epilepsy. ( Buschhoff, AS; de Mooij-van Malsen, JG; Scherließ, R; Schiffelholz, T; Stephani, U; Wulff, P, 2022) |
| " As adjunctive therapies, topiramate ranked best for GTCA as well as overall for IGEs, while levetiracetam ranked best for myoclonic seizures." | 5.41 | Antiseizure medications for idiopathic generalized epilepsies: a systematic review and network meta-analysis. ( Chu, H; Shi, J; Yang, X; Zhang, X; Zhou, Z, 2023) |
| "Ethosuximide (ESX) is a drug of choice for the symptomatic treatment of absence seizures." | 3.79 | Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy. ( Blumenfeld, H; Dezsi, G; Jones, NC; O'Brien, TJ; Ozturk, E; Powell, KL; Stanic, D, 2013) |
| " Following treatment with antiepileptic drugs (AEDs), the patient developed several rare complications: after beginning therapy with phenytoin, the patient developed pseudolymphoma; after monotherapy with carbamazepine (CBZ), the patient thereafter developed myoclonic jerks of upper and lower limbs upon awakening; after one year of treatment with valproate (VPA) the patient developed clinical and immuno-haematological signs of SLE." | 3.69 | Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p. ( Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G, 1996) |
| "Ethosuximide has been associated with a wide variety of idiosyncratic reactions and with hematopoietic adverse effects." | 2.44 | Ethosuximide: from bench to bedside. ( Gören, MZ; Onat, F, 2007) |
| "Intrathecal administration of antiseizure drugs (ASDs) e." | 1.72 | Intrathecal application of ethosuximide is highly efficient in suppressing seizures in a genetic model of absence epilepsy. ( Buschhoff, AS; de Mooij-van Malsen, JG; Scherließ, R; Schiffelholz, T; Stephani, U; Wulff, P, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Buschhoff, AS | 1 |
| Scherließ, R | 1 |
| de Mooij-van Malsen, JG | 1 |
| Schiffelholz, T | 1 |
| Stephani, U | 1 |
| Wulff, P | 1 |
| Chu, H | 1 |
| Zhang, X | 1 |
| Shi, J | 1 |
| Zhou, Z | 1 |
| Yang, X | 1 |
| Brigo, F | 1 |
| Striano, P | 1 |
| Belcastro, V | 1 |
| Dezsi, G | 1 |
| Ozturk, E | 1 |
| Stanic, D | 1 |
| Powell, KL | 1 |
| Blumenfeld, H | 1 |
| O'Brien, TJ | 1 |
| Jones, NC | 1 |
| Gören, MZ | 1 |
| Onat, F | 1 |
| Ribacoba Montero, R | 1 |
| Salas Puig, J | 1 |
| Ferreiro Martín, D | 1 |
| Ono, K | 1 |
| Baba, H | 1 |
| Sugai, S | 1 |
| Gigli, GL | 1 |
| Scalise, A | 1 |
| Silvestri, G | 1 |
| Diomedi, M | 1 |
| Placidi, F | 1 |
| Pomponi, MG | 1 |
| Masala, C | 1 |
| Ribacoba, R | 1 |
| Salas-Puig, J | 1 |
| Solar, DM | 1 |
| Otero, B | 1 |
| Herranz, JL | 1 |
3 reviews available for ethosuximide and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Antiseizure medications for idiopathic generalized epilepsies: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Child; Epilepsy, Generalized; Ethosuximide; Humans; Levetiracetam; Network Meta-Ana | 2023 |
A reappraisal of atypical absence seizures in children and adults: therapeutic implications.
Topics: Anticonvulsants; Epilepsy, Generalized; Ethosuximide; Humans; Lamotrigine; Lennox Gastaut Syndrome; | 2019 |
Ethosuximide: from bench to bedside.
Topics: Animals; Anticonvulsants; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, Generalized; Ethosux | 2007 |
6 other studies available for ethosuximide and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Intrathecal application of ethosuximide is highly efficient in suppressing seizures in a genetic model of absence epilepsy.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; E | 2022 |
Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy.
Topics: Aging; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Body Weight; Brain; DNA (Cytosine-5-)-Me | 2013 |
[Absence seizures in adulthood: four cases].
Topics: Adult; Age Factors; Age of Onset; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absen | 1994 |
A new chronic model of spontaneous nonconvulsive generalized seizures.
Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Callosum; Electroencephalography; Epilepsy, Absenc | 1993 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromoso | 1996 |
[The efficacy of the valproic acid-ethosuximide combination in the continuous slow point wave syndrome during sleep].
Topics: Anticonvulsants; Brain; Child; Electroencephalography; Epilepsy, Generalized; Ethosuximide; Female; | 1997 |