ethosuximide has been researched along with Brain Injuries in 2 studies
Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute seizures frequently occur following severe traumatic brain injury (TBI) and have been associated with poor patient prognosis." | 5.39 | Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats. ( Lu, XC; Marcsisin, SR; Melendez, V; Mountney, A; Potter, B; Shear, DA; Sousa, J; Tortella, FC, 2013) |
| "Acute seizures frequently occur following severe traumatic brain injury (TBI) and have been associated with poor patient prognosis." | 1.39 | Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats. ( Lu, XC; Marcsisin, SR; Melendez, V; Mountney, A; Potter, B; Shear, DA; Sousa, J; Tortella, FC, 2013) |
| "Nonconvulsive seizures (NCSs) after traumatic and ischemic brain injury are often refractory to antiepileptic drug therapy and are associated with a decline in patient outcome." | 1.32 | Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. ( Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mountney, A | 1 |
| Shear, DA | 1 |
| Potter, B | 1 |
| Marcsisin, SR | 1 |
| Sousa, J | 1 |
| Melendez, V | 1 |
| Tortella, FC | 2 |
| Lu, XC | 1 |
| Williams, AJ | 1 |
| Lu, XM | 1 |
| Moreton, JE | 1 |
| Hartings, JA | 1 |
2 other studies available for ethosuximide and Brain Injuries
| Article | Year |
|---|---|
Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats.
Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Dose-Response Relationship, Drug; Electroencephalog | 2013 |
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia.
Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarbo | 2004 |