Page last updated: 2024-10-26

ethosuximide and Anxiety

ethosuximide has been researched along with Anxiety in 9 studies

Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Chronic pain is a heavy burden disease."5.51Ethosuximide improves chronic pain-induced anxiety- and depression-like behaviors. ( Boudieu, L; Bourdier, J; Daulhac, L; Eschalier, A; Kerckhove, N; Mallet, C; Ourties, G, 2019)
"The anticonvulsant drug ethosuximide has shown diverse anxiety-related activity in rodents, but research in zebrafish is limited."3.85Behavioural responses of zebrafish larvae to acute ethosuximide exposure. ( Guo, N; Ji, Y; Li, F; Li, Q; Lin, J; Liu, X; Peng, X; Zhang, Y, 2017)
"Ethosuximide (ESX) is a drug of choice for the symptomatic treatment of absence seizures."3.79Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy. ( Blumenfeld, H; Dezsi, G; Jones, NC; O'Brien, TJ; Ozturk, E; Powell, KL; Stanic, D, 2013)
"Chronic pain is a heavy burden disease."1.51Ethosuximide improves chronic pain-induced anxiety- and depression-like behaviors. ( Boudieu, L; Bourdier, J; Daulhac, L; Eschalier, A; Kerckhove, N; Mallet, C; Ourties, G, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Tomczuk, BE1
Taylor, CR1
Moses, LM1
Sutherland, DB1
Lo, YS1
Johnson, DN1
Kinnier, WB1
Kilpatrick, BF1
Kaur, S1
Maslov, LN1
Singh, N1
Jaggi, AS1
Kerckhove, N1
Boudieu, L1
Ourties, G1
Bourdier, J1
Daulhac, L1
Eschalier, A1
Mallet, C1
Zhang, K1
Jia, G1
Xia, L1
Du, J1
Gai, G1
Wang, Z1
Cao, L1
Zhang, F1
Tao, R1
Liu, H1
Hashimoto, K1
Wang, G1
Cao, F1
Liu, JJ1
Zhou, S1
Cortez, MA1
Snead, OC1
Han, J1
Jia, Z1
Ji, Y1
Lin, J1
Peng, X1
Liu, X1
Li, F1
Zhang, Y1
Guo, N1
Li, Q1
Dezsi, G1
Ozturk, E1
Stanic, D1
Powell, KL1
Blumenfeld, H1
O'Brien, TJ1
Jones, NC1
Shaw, FZ1
Chuang, SH1
Shieh, KR1
Wang, YJ1
Bertoglio, LJ1
Zangrossi, H1

Reviews

1 review available for ethosuximide and Anxiety

ArticleYear
Dual role of T-type calcium channels in anxiety-related behavior.
    Journal of basic and clinical physiology and pharmacology, 2019, Oct-23, Volume: 31, Issue:3

    Topics: Animals; Anxiety; Calcium; Calcium Channels, T-Type; Ethosuximide

2019

Trials

1 trial available for ethosuximide and Anxiety

ArticleYear
Efficacy of anticonvulsant ethosuximide for major depressive disorder: a randomized, placebo-control clinical trial.
    European archives of psychiatry and clinical neuroscience, 2021, Volume: 271, Issue:3

    Topics: Adult; Anticonvulsants; Anxiety; Depressive Disorder, Major; Double-Blind Method; Ethosuximide; Fema

2021

Other Studies

7 other studies available for ethosuximide and Anxiety

ArticleYear
2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as non-benzodiazepine anticonvulsants and anxiolytics.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Binding, Competitive; Cereb

1991
Ethosuximide improves chronic pain-induced anxiety- and depression-like behaviors.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019, Volume: 29, Issue:12

    Topics: Animals; Anticonvulsants; Anxiety; Calcium Channel Blockers; Calcium Channels, T-Type; Chronic Pain;

2019
Neuroligin 2 regulates absence seizures and behavioral arrests through GABAergic transmission within the thalamocortical circuitry.
    Nature communications, 2020, 07-27, Volume: 11, Issue:1

    Topics: Action Potentials; Animals; Anxiety; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Electrodes

2020
Behavioural responses of zebrafish larvae to acute ethosuximide exposure.
    Behavioural pharmacology, 2017, Volume: 28, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Behavior, Animal; Darkness; Ethosuximide; La

2017
Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy.
    Epilepsia, 2013, Volume: 54, Issue:4

    Topics: Aging; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Body Weight; Brain; DNA (Cytosine-5-)-Me

2013
Depression- and anxiety-like behaviors of a rat model with absence epileptic discharges.
    Neuroscience, 2009, May-05, Volume: 160, Issue:2

    Topics: Action Potentials; Animals; Anticonvulsants; Anxiety; Depression; Disease Models, Animal; Epilepsy,

2009
Involvement of dorsolateral periaqueductal gray N-methyl-D-aspartic acid glutamate receptors in the regulation of risk assessment and inhibitory avoidance behaviors in the rat elevated T-maze.
    Behavioural pharmacology, 2006, Volume: 17, Issue:7

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Anxiety; Ethosuximide; Excitatory Amino Acid

2006