ethosuximide has been researched along with Allodynia in 6 studies
Ethosuximide: An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
ethosuximide : A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cold-and mechano-allodynia and thermal hyperalgesia were measured prior to surgery (the day 0) and 3, 5, 7, 14 and 21 days post surgery." | 5.38 | Ethosuximide reduces allodynia and hyperalgesia and potentiates morphine effects in the chronic constriction injury model of neuropathic pain. ( Arani, MN; Banafshe, HR; Hamidi, GA; Mesdaghinia, A; Ramezani, MH; Talaei, SA, 2012) |
| "Neuropathic pain was induced by administration of vincristine (50 µg/kg, i." | 1.56 | Pain attenuating actions of vincristinet-preconditioning in chemotherapeutic agent-induced neuropathic pain: key involvement of T-type calcium channels. ( Jaggi, AS; Maslov, LN; Sharma, J; Singh, N, 2020) |
| "The cold-and mechano-allodynia and thermal hyperalgesia were measured prior to surgery (the day 0) and 3, 5, 7, 14 and 21 days post surgery." | 1.38 | Ethosuximide reduces allodynia and hyperalgesia and potentiates morphine effects in the chronic constriction injury model of neuropathic pain. ( Arani, MN; Banafshe, HR; Hamidi, GA; Mesdaghinia, A; Ramezani, MH; Talaei, SA, 2012) |
| "Thermal hyperalgesia and mechanical allodynia occurred in both hind paws and forepaws by 7 d postlesion and were maintained >31 d." | 1.35 | Maladaptive homeostatic plasticity in a rodent model of central pain syndrome: thalamic hyperexcitability after spinothalamic tract lesions. ( Thompson, SM; Wang, G, 2008) |
| " Hill slope coefficients for the tested anticonvulsants indicate that the dose-response curve was less steep for gabapentin than for phenytoin, carbamazepine and ethosuximide." | 1.32 | Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats. ( Jevtovic-Todorovic, V; Rastogi, AJ; Todorovic, SM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yogeeswari, P | 1 |
| Ragavendran, JV | 1 |
| Sriram, D | 1 |
| Nageswari, Y | 1 |
| Kavya, R | 1 |
| Sreevatsan, N | 1 |
| Vanitha, K | 1 |
| Stables, J | 1 |
| Sharma, J | 1 |
| Maslov, LN | 1 |
| Singh, N | 1 |
| Jaggi, AS | 1 |
| Wang, G | 1 |
| Thompson, SM | 1 |
| Hamidi, GA | 1 |
| Ramezani, MH | 1 |
| Arani, MN | 1 |
| Talaei, SA | 1 |
| Mesdaghinia, A | 1 |
| Banafshe, HR | 1 |
| Todorovic, SM | 1 |
| Rastogi, AJ | 1 |
| Jevtovic-Todorovic, V | 1 |
| Barton, ME | 1 |
| Eberle, EL | 1 |
| Shannon, HE | 1 |
6 other studies available for ethosuximide and Allodynia
| Article | Year |
|---|---|
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; | 2007 |
Pain attenuating actions of vincristinet-preconditioning in chemotherapeutic agent-induced neuropathic pain: key involvement of T-type calcium channels.
Topics: Amlodipine; Animals; Antineoplastic Agents; Calcium; Calcium Channel Blockers; Calcium Channels, T-T | 2020 |
Maladaptive homeostatic plasticity in a rodent model of central pain syndrome: thalamic hyperexcitability after spinothalamic tract lesions.
Topics: Action Potentials; Adaptation, Physiological; Animals; Calcium Channel Blockers; Calcium Channels, T | 2008 |
Ethosuximide reduces allodynia and hyperalgesia and potentiates morphine effects in the chronic constriction injury model of neuropathic pain.
Topics: Analgesics, Opioid; Animals; Calcium Channel Blockers; Cold Temperature; Constriction; Disease Model | 2012 |
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyc | 2003 |
The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil.
Topics: Animals; Anticonvulsants; Behavior, Animal; Calcium Channel Blockers; Calcium Channels, T-Type; Dose | 2005 |