ethiprole and Body-Weight

Few studies were found for neurobehavioral toxicity of the phenylpyrazole insecticide ethiprole in mammals. This study was designed to evaluate the reproductive and neurobehavioral effects of ethiprole exposure in mice.. Ethiprole was given in the diet to provide levels of 0 (control), 0.0003, 0.0009, and 0.0027% from 5 weeks of age of the F. Movement time increased with a significant dose-related trend, and frequencies of mice with urination increased in the high-dose group of adult males in the F. The dose levels of ethiprole in the present study produced several adverse effects in neurobehavioral parameters in mice. Birth Defects Research 109:1568-1585, 2017. © 2017 Wiley Periodicals, Inc.

Topics: Animals; Behavior, Animal; Body Weight; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Mice; Pyrazoles; Reproduction