ethionine has been researched along with Choline Deficiency in 113 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (33.63) | 18.7374 |
| 1990's | 36 (31.86) | 18.2507 |
| 2000's | 20 (17.70) | 29.6817 |
| 2010's | 17 (15.04) | 24.3611 |
| 2020's | 2 (1.77) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, X; Dong, H; Gu, T; Guo, Y; Li, B; Li, F; Lu, L; Shen, B; Shen, Z; Xu, X; Zhu, J | 1 |
| Biczo, G; Dawson, D; Elperin, J; French, SW; Gorelick, FS; Gretler, S; Gukovskaya, AS; Gukovsky, I; Hegyi, P; Husain, SZ; Lotshaw, E; Lugea, A; Malla, SR; Mareninova, OA; Rakonczay, Z; Ruchala, P; Shalbueva, N; Vegh, ET; Wen, L; Whitelegge, J | 1 |
| Elsegood, CL; Giles, C; Gogoi-Tiwari, J; Gratte, FD; Köhn-Gaone, J; McCaughan, GW; Olynyk, JK; Ramm, GA; Schmidt-Arras, D; Tirnitz-Parker, JEE | 1 |
| Cornuet, P; Kakar, S; Michael, AA; Molina, L; Monga, SP; Nejak-Bowen, KN; Poddar, M; Pradhan-Sundd, T; Russell, JO; Singh, S; Sundd, P; Vats, R; Watkins, SC | 1 |
| Guo, Y; Lei, Y; Lin, X; Liu, H; Tan, S; Tao, L; Wu, B; Zheng, F | 1 |
| Cao, H; Ciofoaia, V; Gay, MD; Huber, M; Kallakury, B; Kroemer, AHK; Kruger, AJ; Nadella, S; Safronenka, A; Shivapurkar, N; Smith, JP; Tucker, RD | 1 |
| Greenbaum, LE; Kaestner, KH; Shin, S; Upadhyay, N | 1 |
| Chen, Y; Fickert, P; Gassler, N; Guldiken, N; Haybaeck, J; Jeon, MK; Mohammed, HH; Pollheimer, MJ; Spurny, M; Strnad, P; Trautwein, C | 1 |
| Bugyik, E; Dezső, K; Nagy, P; Paku, S; Rókusz, A; Szabó, V; Szücs, A | 1 |
| Hamada, K; Isayama, H; Kanazashi, S; Takeuchi, K; Yamaguchi, I; Yoshida, M | 1 |
| Akhurst, B; Knight, B; Olynyk, JK; Ramm, GA; Ruddell, RG; Subramaniam, VN; Summerville, L; Tirnitz-Parker, JE | 1 |
| Abarca-Quinones, J; Horsmans, Y; Leclercq, IA; Sempoux, C; Van Hul, NK | 1 |
| An, W; Bai, Y; Cong, M; Jia, J; Liu, T; Wang, B; Wang, P; Wu, X; Yin, C; You, H | 1 |
| Abraham, LJ; Curtis, D; Knight, B; Tonkin, JN; Yeoh, GC | 1 |
| Aharoni-Simon, M; Artan, A; Madar, Z; Ramadori, G; Tirosh, O | 1 |
| Jakubowski, A; Klopcic, BR; Knight, B; Olynyk, JK; Tirnitz-Parker, JE; Viebahn, CS; Yeoh, GC | 1 |
| Araki, K; Baba, H; Hiramatsu, S; Hirota, M; Ida, S; Ohmuraya, M; Ozaki, N; Takamori, H; Uehara, H; Yamamura, K | 1 |
| Guest, I; Ilic, Z; Sell, S | 1 |
| Alison, MR; Fallowfield, JA; Forbes, SJ; Goldin, RD; Iredale, JP; Kallis, YN; Robson, AJ; Thomas, HC; Wright, NA | 1 |
| Brouillet, A; Chobert, MN; Couchie, D; Fourcot, A; Laperche, Y; Mavier, P; Zafrani, ES | 1 |
| Akita, S; Kobayashi, A; Kubota, K; Misawa, R; Miyagawa, S; Nakata, T; Shimizu, A; Takahashi, M; Yokoyama, T | 1 |
| Brilliant, KE; Cerretti, B; Claro, P; Clift, D; Gruppuso, PA; Hixson, DC; Mills, DR; Patel, A; Sanders, JA | 1 |
| Fukuda, A; Hebrok, M; Morris, JP | 1 |
| Bobowiec, R; Kostro, K; Lisiecka, U; Wojcik, M | 1 |
| Croager, EJ; Smith, PG; Yeoh, GC | 1 |
| Bottiglieri, T; Chen, L; Gukovsky, I; Huang, ZZ; Lu, SC; Lugea, A; Mato, JM; Pandol, SJ; Reyes, CN | 1 |
| SALMON, WD; SMITH, RC | 1 |
| Omary, MB; Resurreccion, EZ; Tao, GZ; Toivola, DM; Zhong, B; Zhou, Q | 1 |
| Azzolino, O; Bosco, O; De Giuli, P; Emanuelli, G; Goffi, A; Hirsch, E; Lupia, E; Montrucchio, G; Patrucco, E; Ricca, M; Vivaldo, MC; Wymann, MP | 1 |
| Abraham, LJ; Akhurst, B; Husk, K; Matthews, V; Smyth, MJ; Yeoh, GC | 1 |
| Fukumitsu, K; Honda, H; Kihara, Y; Otsuki, M; Yamaguchi, T; Yoshikawa, H | 1 |
| Abraham, LJ; Akhurst, B; Croager, EJ; Klinken, E; Knight, B; Matthews, VB; Olynyk, JK; Yeoh, G | 1 |
| De Man, JG; De Winter, BY; Herman, AG; Pelckmans, PA; Seerden, TC; Van Den Bossche, RM | 1 |
| Davies, RA; Knight, B; Olynyk, JK; Tian, YW; Yeoh, GC | 1 |
| Blackwell, TS; Chapman, WC; Christman, JW; Gray, KD; May, AK; Parman, KS; Simovic, MO; Stain, SC | 1 |
| Abraham, LJ; Akhurst, B; Knight, B; Matthews, VB; Olynyk, JK; Ramm, GA; Ruddell, RG; Yeoh, GC | 1 |
| Manabe, T; Steer, ML | 4 |
| Gilliland, L; Steer, ML | 1 |
| Gilliland, EL; Steer, ML; Turner, N | 1 |
| Fausto, N; Hayner, NT; Yaswen, P | 1 |
| Koike, H; Meldolesi, J; Steer, ML | 1 |
| Abe, M; Adachi, J; Iwasaki, T; Miyamoto, S; Murai, S; Nagata, K; Nakata, M; Nohara, A; Watanabe, M; Watanabe, Y; Yamamoto, W | 1 |
| Baccino, FM; Lombardi, B; Rao, KN; Zuretti, MF | 1 |
| Kaiser, AM; Saluja, AK; Saluja, M; Sengupta, A; Steer, ML | 1 |
| Doi, R; Echigo, Y; Higashide, S; Imamura, M; Inoue, K; Kaji, H; Kogire, M; Sumi, S | 1 |
| Radaeva, S; Steinberg, P | 1 |
| Dianzani, MU; Greco, M; Pani, P; Sesca, E; Tessitore, L | 1 |
| Huang, WH; Kirilak, Y; Morgan, RH; Tee, LB; Yeoh, GC | 1 |
| Blumrich, M; Oesch, F; Pack, R; Petzinger, E; Steinberg, P | 1 |
| Fernández-del Castillo, C; Foitzik, T; Lewandrowski, KB; Rattner, DW; Warshaw, AL | 1 |
| Eigenbrodt, E; Oesch, F; Steinberg, P; Weisse, G | 1 |
| Lenzen, R; Lenzi, R; Rijhsinghani, K; Salvi, R; Schuler, E; Tarsetti, F; Tavoloni, N | 1 |
| Fujimoto, K; Hatayama, I; Kaneda, T; Miyazawa, T; Sato, K; Yoshida, LS | 1 |
| Hiruma, M; Kurihara, T; Ono, A; Seki, A | 1 |
| Habara, Y; Imamura, M; Kanno, T; Manabe, T; Ohshio, G; Okada, N | 1 |
| De Dios, I; Garcia-Montero, AC; Manso, MA; Rodriguez, AI | 1 |
| Andoh, N; Fukuda, T; Kido, A; Kitada, H; Kobayashi, E; Mizumoto, Y; Nakae, D; Ohashi, K; Tsujiuchi, T; Tsutsumi, M | 1 |
| Carter, G; Fink, GW; Norman, JG; Sexton, C | 1 |
| Andoh, N; Denda, A; Endoh, T; Kitada, H; Kobayashi, E; Konishi, Y; Mizumoto, Y; Nakae, D; Tsujiuchi, T; Tsutsumi, M | 1 |
| Affigne, S; Faris, RA; Hixson, DC; McBride, AC | 1 |
| Blanco, I; Chabás, A; Clavé, P; Farré, A; Guillaumes, S; Lluís, F; Sans, MD; Villanueva, A | 1 |
| Smith, PG; Tian, YW; Yeoh, GC | 1 |
| Ashley, SW; Gloor, B; Lane, JS; Lewis, MP; Reber, HA; Todd, KE | 1 |
| Yamaguchi, I; Yoshino, T | 1 |
| Sell, S | 1 |
| Bannasch, P; Hacker, HJ; Steinberg, P | 1 |
| Furuhama, K; Yabe, K | 1 |
| Bhagat, L; Bhatia, M; Frossard, JL; Hofbauer, B; Lee, HS; Saluja, A; Steer, ML | 1 |
| Affigne, S; Brown, J; Hixson, DC; McBride, AC | 1 |
| Bunnett, NW; Drasin, TE; Grady, EF; Hutter, MM; Kim, EH; Kirkwood, KS; Maa, J; Yoshimi, SK | 1 |
| Bahjat, FR; Copeland, EM; Ferry, MA; Hutchins, B; LaFace, D; Minter, RM; Moldawer, LL; Murday, ME; Oberholzer, A; Oberholzer, C; Shinoda, J; Tannahill, CL; Wen, S | 1 |
| Akhurst, B; Croager, EJ; Dumble, ML; Farley-Roche, CA; Knight, B; Ong, JK; Yeoh, GC | 1 |
| Iammarino, RM; Lombardi, B; Sell, S; Shinozuka, H | 1 |
| Amicucci, G; Ciani, R; De Bernardinis, G; Negro, P; Risetti, A; Tuscano, D | 1 |
| Lombardi, B | 1 |
| Estes, LW; Lombardi, B; Longnecker, DS | 1 |
| Lombardi, B; Rao, NK | 1 |
| Steer, ML | 1 |
| Frey, CF; Isaji, S; Ruebner, B; Stanten, R; Suzuki, M | 1 |
| Smith, PG; Tee, LB; Yeoh, GC | 1 |
| Carlson, J; Frey, CF; Isaji, S; Ruebner, B; Suzuki, M | 1 |
| Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, MC | 1 |
| Borchard, F; Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, M; Strohmeyer, G; Ude, K | 1 |
| Christy, MD; Leight, GS; Lobaugh, B; Schachter, PP | 1 |
| Bannasch, P; Dienes, HP; Hacker, HJ; Oesch, F; Steinberg, P | 1 |
| Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, M; Strohmeyer, G; Ude, K | 1 |
| Fujimoto, K; Kaneda, T; Miyazawa, T; Yoshida, LS | 1 |
| Denda, A; Kitazawa, S; Konishi, Y; Mizumoto, K; Tsutsumi, M | 1 |
| Allison, JP; Hixson, DC | 1 |
| Fausto, N; Panzica, M; Petropoulos, CJ; Yaswen, P | 1 |
| Houlihan, MJ; Powers, RE; Saluja, AK; Steer, ML | 1 |
| Ferrell, LD; Grendell, JH; Liddle, RA; Niederau, C | 1 |
| Powers, RE; Rutledge, PL; Saluja, AK; Steer, ML | 1 |
| Bank, S; Ilardi, C; Kranz, V; Lendvai, S; Silverman, M | 1 |
| Gomez, G; Green, D; Rajaraman, S; Thompson, JC; Townsend, CM; Uchida, T | 1 |
| Abrams, W; Conn, MI; Deren, J; Kueppers, F; Weinbaum, G | 1 |
| Imanishi, K; Kyogoku, T; Manabe, T; Nonaka, A; Tamura, K; Tobe, T; Yamaki, K | 1 |
| Leli, U; Ohshio, G; Saluja, A; Sengupta, A; Steer, ML | 1 |
| Evces, S; Lindahl, R | 1 |
| Denda, A; Konishi, Y; Mizumoto, K; Tsutsumi, M | 1 |
| Ferrell, LD; Grendell, JH; Niederau, C | 1 |
| Farber, E; Ghoshal, AK; Sarma, DS | 1 |
| Fausto, N; Miller, KR; Spelman, LH; Thompson, NL | 1 |
| Adham, NF; Coelle, EF; Taylor, IL | 1 |
| Akdamar, K; Chen, IL; Degertekin, H; Ertan, A; Vaupel, R; Yates, R | 1 |
| Francis, KT; Smith, RC | 1 |
| Olmsted, CA | 1 |
| Cornatzer, WE; Miller, JE | 1 |
| Sidransky, H; Verney, E | 1 |
| Harrington, DH; Newberne, PM; Wogan, GN | 1 |
3 review(s) available for ethionine and Choline Deficiency
| Article | Year |
|---|---|
Influence of dietary factors on the pancreatotoxicity of ethionine.
Topics: Acute Disease; Age Factors; Animals; Choline Deficiency; Diet; Disease Models, Animal; Enzyme Precursors; Ethionine; Female; Hemorrhage; Humans; Male; Methionine; Necrosis; Pancreas; Pancreatitis; Phosphatidylcholines; Sex Factors | 1976 |
How and where does acute pancreatitis begin?
Topics: Acute Disease; Amino Acids; Amylases; Animals; Ceruletide; Cholelithiasis; Choline Deficiency; Disease Models, Animal; Edema; Enzyme Precursors; Ethionine; Hydrolases; Mice; Pancreatitis; Protein Biosynthesis; Proteins; Rabbits | 1992 |
Acute experimental hemorrhagic-necrotizing pancreatitis induced by feeding a choline-deficient, ethionine-supplemented diet. Methodology and standards.
Topics: Acute Disease; Animals; Choline Deficiency; Diet; Disease Models, Animal; Ethionine; Female; Hemorrhage; Mice; Necrosis; Pancreatitis | 1992 |
110 other study(ies) available for ethionine and Choline Deficiency
| Article | Year |
|---|---|
TGF-β/YB-1/Atg7 axis promotes the proliferation of hepatic progenitor cells and liver fibrogenesis.
Topics: Animals; Autophagy; Autophagy-Related Protein 7; Cell Proliferation; Chemical and Drug Induced Liver Injury; Choline Deficiency; Disease Models, Animal; Ethionine; Extracellular Matrix; Gene Expression Regulation; Liver; Liver Cirrhosis; Mice, Knockout; Microscopy, Electron, Transmission; Pyridines; Stem Cells; Transcription Factors; Transforming Growth Factor beta | 2022 |
Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.
Topics: Acute Disease; Animals; Arginine; Autophagy; Bile Acids and Salts; Calcium Signaling; Ceruletide; Choline Deficiency; Cyclophilins; Disease Models, Animal; Endoplasmic Reticulum Stress; Ethionine; Genetic Predisposition to Disease; Humans; Lipid Metabolism; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Proton-Translocating ATPases; Pancreas; Pancreatitis; Peptidyl-Prolyl Isomerase F; Phenotype; Rats; Time Factors; Trehalose | 2018 |
The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury.
Topics: Animals; Cell Proliferation; Choline Deficiency; Diet; Dietary Supplements; Disease Models, Animal; Ethionine; Liver; Lung Injury; Male; Mice; Mice, Inbred C57BL | 2017 |
Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice.
Topics: Animals; Bile; Biological Transport; Chemical and Drug Induced Liver Injury, Chronic; Choline Deficiency; Claudins; Disease Models, Animal; Ethionine; Hepatocytes; Kinetics; Liver; Membrane Transport Proteins; Mice, Inbred C57BL; Permeability; Pyridines; Tight Junctions | 2018 |
β-Arrestin1 alleviates acute pancreatitis via repression of NF-κBp65 activation.
Topics: Acute Disease; Animals; beta-Arrestin 1; Cell Line, Tumor; Ceruletide; Choline Deficiency; Disease Models, Animal; Down-Regulation; Ethionine; Female; Humans; Interleukin-1beta; Interleukin-6; Mice, Knockout; Pancreatitis; Phosphorylation; Survival Rate; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2019 |
A Cholecystokinin Receptor Antagonist Halts Nonalcoholic Steatohepatitis and Prevents Hepatocellular Carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Choline Deficiency; Disease Models, Animal; Epigenesis, Genetic; Ethionine; Female; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Liver; Liver Neoplasms; Mice, Inbred C57BL; MicroRNAs; Non-alcoholic Fatty Liver Disease; Proglumide; Receptor, Cholecystokinin B; Signal Transduction | 2020 |
Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury.
Topics: Animals; Bacterial Proteins; Bile Ducts, Intrahepatic; Cell Death; Cell Lineage; Cell Proliferation; Chemical and Drug Induced Liver Injury; Choline Deficiency; Disease Models, Animal; DNA Damage; Ethionine; Female; Forkhead Transcription Factors; Heparin-binding EGF-like Growth Factor; Hepatocytes; Integrases; Liver; Liver Regeneration; Luminescent Proteins; Male; Mice, Knockout; Oxidative Stress; Pyridines; RNA, Untranslated; Signal Transduction; Stem Cells; Time Factors | 2015 |
Loss of keratin 19 favours the development of cholestatic liver disease through decreased ductular reaction.
Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis, Extrahepatic; Cholic Acid; Choline Deficiency; Common Bile Duct; Disease Models, Animal; Epithelial Cells; Ethionine; Keratin-19; Ligation; Liver; Liver Cirrhosis, Biliary; Liver Regeneration; Male; Mice, Knockout; Phenotype; Pyridines; Signal Transduction; Stem Cells; Time Factors | 2015 |
Imatinib accelerates progenitor cell-mediated liver regeneration in choline-deficient ethionine-supplemented diet-fed mice.
Topics: Animals; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Ethionine; Hepatocytes; Imatinib Mesylate; Liver Cirrhosis; Liver Regeneration; Male; Mice, Inbred C57BL; Protein Kinase Inhibitors; Stem Cells | 2016 |
Risperidone attenuates local and systemic inflammatory responses to ameliorate diet-induced severe necrotic pancreatitis in mice: it may provide a new therapy for acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Choline Deficiency; Ethionine; Female; Inflammation; Interleukin-6; Lipase; Mice; Mice, Inbred ICR; Pancreatitis; Pancreatitis, Acute Necrotizing; Risperidone; Survival Analysis | 2009 |
Lymphotoxin-beta receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury.
Topics: Animals; Cell Line; Cell Proliferation; Cells, Cultured; Choline Deficiency; Collagen Type I; Disease Models, Animal; Ethionine; Hepatic Stellate Cells; Liver; Liver Regeneration; Lymphotoxin alpha1, beta2 Heterotrimer; Lymphotoxin beta Receptor; Male; Mice; Rats; Wound Healing | 2009 |
Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
Topics: Animals; Cell Differentiation; Cell Proliferation; Choline Deficiency; Disease Models, Animal; Ethionine; Extracellular Matrix; Gene Expression Profiling; Hepatic Stellate Cells; Liver; Liver Diseases; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Time Factors | 2009 |
Expression of extracellular matrix genes in cultured hepatic oval cells: an origin of hepatic stellate cells through transforming growth factor beta?
Topics: Albumins; alpha-Fetoproteins; Animals; Antimetabolites; Bile Ducts; Biomarkers; Cadherins; Cell Differentiation; Cell Survival; Cells, Cultured; Choline Deficiency; Desmin; Disease Models, Animal; Ethionine; Extracellular Matrix Proteins; Gene Expression; Glial Fibrillary Acidic Protein; Hepatocytes; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stem Cells; Transforming Growth Factor beta | 2009 |
Bone marrow cells play only a very minor role in chronic liver regeneration induced by a choline-deficient, ethionine-supplemented diet.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Choline Deficiency; Diet; Disease Models, Animal; Ethionine; Liver; Liver Diseases; Liver Regeneration; Mice; Mice, Congenic; Treatment Outcome | 2008 |
Impaired liver glucose production in a murine model of steatosis and endotoxemia: protection by inducible nitric oxide synthase.
Topics: Animals; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Endotoxemia; Ethionine; Fatty Liver; Glucose; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II | 2010 |
Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells.
Topics: Animals; Cell Proliferation; Choline Deficiency; Collagen; Cytokine TWEAK; Ethionine; Liver; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogens; Mitosis; NF-kappa B; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Stem Cells; Tumor Necrosis Factors; TWEAK Receptor | 2010 |
Chronic pancreatitis in mice by treatment with choline-deficient ethionine-supplemented diet.
Topics: Amylases; Animal Feed; Animals; Biomarkers; Blotting, Western; Choline Deficiency; Disease Models, Animal; ErbB Receptors; Ethionine; Female; Glycoproteins; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis, Chronic; Prostatic Secretory Proteins; ras Proteins; Transforming Growth Factor alpha; Trypsin Inhibitor, Kazal Pancreatic | 2010 |
Age dependence of oval cell responses and bile duct carcinomas in male fischer 344 rats fed a cyclic choline-deficient, ethionine-supplemented diet.
Topics: Administration, Oral; Aging; Animals; Antimetabolites; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Choline Deficiency; Diet; Ethionine; Liver; Liver Neoplasms; Male; Pancreas; Rats; Rats, Inbred F344 | 2010 |
Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Choline Deficiency; Collagen; Ethionine; Extracellular Matrix; Female; Laminin; Liver Cirrhosis, Experimental; Liver Regeneration; Macrophages; Male; Mice; Mice, Inbred C57BL; Stem Cells | 2011 |
Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice.
Topics: Animals; Axl Receptor Tyrosine Kinase; Carbon Tetrachloride; Cell Proliferation; Choline Deficiency; Disease Progression; Ethionine; Fatty Liver; Gene Expression Regulation; Hepatitis; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Lipid Metabolism; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Stem Cells; Thioacetamide; Time Factors | 2011 |
Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet.
Topics: Animals; Bone Marrow Cells; Chimerism; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Ethionine; Fibrosis; Green Fluorescent Proteins; Male; Pancreas; Pancreatic Stellate Cells; Pancreatitis; Platelet-Derived Growth Factor; Rats; Rats, Inbred Lew; Transforming Growth Factor beta | 2012 |
The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Cell Proliferation; Cell Shape; Cell Transformation, Neoplastic; Choline Deficiency; Diethylnitrosamine; Dual-Specificity Phosphatases; Ethionine; Fluorenes; Gene Expression Profiling; Hepatectomy; Hepatocytes; Liver Neoplasms, Experimental; Male; Mechanistic Target of Rapamycin Complex 1; Mitogen-Activated Protein Kinase Phosphatases; Multiprotein Complexes; Precancerous Conditions; Proteins; Rats; Sirolimus; TOR Serine-Threonine Kinases | 2012 |
Bmi1 is required for regeneration of the exocrine pancreas in mice.
Topics: Acute Disease; Animals; Apoptosis; Bone Marrow Transplantation; Cell Differentiation; Cell Proliferation; Ceruletide; Choline Deficiency; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Ethionine; Female; Gene Expression Regulation; Green Fluorescent Proteins; Mice; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Pancreas, Exocrine; Pancreatitis; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Regeneration; Repressor Proteins; Time Factors; Tissue Culture Techniques; Transplantation Chimera; Tumor Suppressor Protein p53 | 2012 |
Proliferation, differentiation and apoptosis of choline deficient ethionine supplemented diet-rat oval cells under the influence of 2-methoxyestradiol.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Biomarkers; Cell Differentiation; Cell Proliferation; Cells, Cultured; Choline Deficiency; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Ethionine; Female; Liver; Rats; Rats, Wistar; Time Factors | 2012 |
Ethanol interactions with a choline-deficient, ethionine-supplemented feeding regime potentiate pre-neoplastic cellular alterations in rat liver.
Topics: alpha-Fetoproteins; Animals; Choline Deficiency; Dietary Supplements; Ethanol; Ethionine; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Isoenzymes; Liver; Male; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Wistar; Time Factors; Transcription, Genetic | 2002 |
Role of S-adenosylmethionine in two experimental models of pancreatitis.
Topics: Administration, Oral; Animals; Ceruletide; Choline Deficiency; Ethionine; Female; Methionine Adenosyltransferase; Mice; Models, Biological; Pancreas; Pancreatitis; S-Adenosylmethionine | 2003 |
NUCLEIC ACID LEVELS IN LIVERS OF RATS FED DIETS DEFICIENT IN CHOLINE OF CONTAINING ETHIONINE.
Topics: Choline; Choline Deficiency; Diet; DNA; Ethionine; Liver; Nucleic Acids; Pharmacology; Proteins; Rats; Research; RNA; Vitamin B Deficiency | 1964 |
Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation.
Topics: Animals; Ceruletide; Choline Deficiency; Diet; Ethionine; Fever; Gene Expression Regulation; Hot Temperature; Intestine, Small; Keratins; Liver; Mice; Mice, Inbred BALB C; NF-kappa B; Organ Specificity; Pancreas; Pancreatitis; RNA, Messenger; Transcriptional Activation; Water | 2004 |
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitis.
Topics: Acute Disease; Animals; Apoptosis; Caspase 3; Caspases; Ceruletide; Choline Deficiency; Class Ib Phosphatidylinositol 3-Kinase; Diet; Dietary Supplements; Ethionine; In Situ Nick-End Labeling; Isoenzymes; Mice; Mice, Knockout; Necrosis; Neutrophils; Pancreatitis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Survival Rate | 2004 |
Differential lymphotoxin-beta and interferon gamma signaling during mouse liver regeneration induced by chronic and acute injury.
Topics: Acute Disease; Animals; Cell Line; Choline Deficiency; Chronic Disease; Diet; DNA-Binding Proteins; Dose-Response Relationship, Drug; Ethionine; Hepatectomy; Interferon-gamma; Liver; Liver Regeneration; Lymphotoxin-alpha; Lymphotoxin-beta; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Stem Cells; Trans-Activators; Tumor Necrosis Factor-alpha; Wounds and Injuries | 2005 |
Natural disruption of group 2 phospholipase A2 gene protects against choline-deficient ethionine-supplemented diet-induced acute pancreatitis and lung injury.
Topics: Acute Disease; Amylases; Animals; Choline Deficiency; Dietary Supplements; Duodenum; Ethionine; Female; Lung; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pancreas; Pancreatitis; Phospholipases A; Phospholipases A2; RNA, Messenger | 2005 |
Liver inflammation and cytokine production, but not acute phase protein synthesis, accompany the adult liver progenitor (oval) cell response to chronic liver injury.
Topics: Acute-Phase Proteins; Animals; Apoptosis; Aspartate Aminotransferases; B-Lymphocytes; Cell Count; Cell Proliferation; Choline Deficiency; Cytokines; Ethionine; Gene Expression Regulation; Hepatitis; Liver; Mice; Mice, Inbred C57BL; RNA, Messenger; T-Lymphocytes; Time Factors | 2005 |
Regional differences in gastrointestinal motility disturbances during acute necrotising pancreatitis.
Topics: Acute Disease; Animals; Carbachol; Choline Deficiency; Dietary Supplements; Dinoprost; Disease Models, Animal; Ethionine; Female; Gastric Emptying; Gastrointestinal Motility; In Vitro Techniques; Mice; Muscle Contraction; Muscle, Smooth; Pancreatitis, Acute Necrotizing; Substance P | 2005 |
Hepatic oval cell response to the choline-deficient, ethionine supplemented model of murine liver injury is attenuated by the administration of a cyclo-oxygenase 2 inhibitor.
Topics: Animals; Antimetabolites; Apoptosis; Cell Proliferation; Choline Deficiency; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diet; Dietary Supplements; Disease Models, Animal; Ethionine; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Microfilament Proteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyruvate Kinase; Stem Cells; Sulfonamides | 2006 |
Activation of nuclear factor kappa B and severe hepatic necrosis may mediate systemic inflammation in choline-deficient/ethionine-supplemented diet-induced pancreatitis.
Topics: Animals; Choline Deficiency; Diet; Dietary Supplements; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ethionine; Inflammation; Liver; Mice; Mice, Inbred C57BL; NF-kappa B; Pancreatitis | 2006 |
Attenuated liver progenitor (oval) cell and fibrogenic responses to the choline deficient, ethionine supplemented diet in the BALB/c inbred strain of mice.
Topics: Animals; Apoptosis; Cell Proliferation; Choline Deficiency; Cytokines; Dietary Supplements; Ethionine; Hepatocytes; Interferon-gamma; Liver Cirrhosis; Liver Regeneration; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Species Specificity; Stem Cells; Th1 Cells | 2007 |
Protective effects of PGE2 on diet-induced acute pancreatitis in mice.
Topics: Amylases; Animals; Cathepsins; Choline Deficiency; Chymotrypsinogen; Diet; Ethionine; Female; In Vitro Techniques; L-Lactate Dehydrogenase; Mice; Pancreatitis; Prostaglandins E; Proteins; Trypsinogen | 1980 |
Effects of ethionine on digestive enzyme synthesis and discharge by mouse pancreas.
Topics: Amylases; Animals; Cholecystokinin; Choline; Choline Deficiency; Chymotrypsinogen; Ethionine; Female; Mice; Pancreas; Trypsinogen | 1980 |
The effects of ethionine administration and choline deficiency on protein carboxymethylase activity in mouse pancreas.
Topics: Adenosine; Amylases; Animals; Choline Deficiency; Dietary Proteins; Ethionine; Female; Mice; Pancreas; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylmethionine | 1981 |
Isolation of oval cells by centrifugal elutriation and comparison with other cell types purified from normal and preneoplastic livers.
Topics: Animals; Cell Separation; Choline Deficiency; Epithelial Cells; Ethionine; Gallbladder; Liver; Liver Neoplasms; Male; Microscopy, Electron; Ploidies; Precancerous Conditions; Rats; Rats, Inbred Strains | 1984 |
Pancreatic effects of ethionine: blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis.
Topics: Animals; Choline Deficiency; Ethionine; Exocytosis; Female; Mice; Microscopy, Electron; Pancreas; Subcellular Fractions | 1982 |
[Studies on experimental pancreatitis induced in rat by ethionine fed with a choline-deficient and low protein diet (author's transl)].
Topics: Animals; Choline Deficiency; Dietary Proteins; Ethionine; Male; Pancreatitis; Rats; Rats, Inbred Strains | 1981 |
Acute hemorrhagic pancreatic necrosis in mice: the activity of lysosomal enzymes in the pancreas and the liver.
Topics: Acid Phosphatase; Animals; Cathepsins; Choline Deficiency; Ethionine; Female; Galactosidases; Hemorrhage; Liver; Lysosomes; Mice; Necrosis; Pancreas; Pancreatic Diseases | 1980 |
Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis.
Topics: Acute Disease; Animals; Apoptosis; Ceruletide; Cholestasis; Choline Deficiency; Constriction, Pathologic; Diet; Ethionine; Female; Male; Mice; Mice, Inbred Strains; Necrosis; Opossums; Pancreatic Ducts; Pancreatitis; Rats; Rats, Wistar | 1995 |
Effects of cyclosporine and tacrolimus (FK 506) on acute pancreatitis in mice.
Topics: Acute Disease; Animals; Ceruletide; Choline Deficiency; Cyclosporine; Edema; Ethionine; Female; Male; Mice; Necrosis; Pancreatitis; Tacrolimus | 1995 |
Phenotype and differentiation patterns of the oval cell lines OC/CDE 6 and OC/CDE 22 derived from the livers of carcinogen-treated rats.
Topics: 3,3'-Diaminobenzidine; Albumins; alpha-Fetoproteins; Animals; Antigens, Neoplasm; Cell Differentiation; Cell Transformation, Neoplastic; Choline Deficiency; Clofibrate; Ethionine; Glucose-6-Phosphatase; Immunohistochemistry; Keratins; Liver; Liver Neoplasms, Experimental; Methylnitronitrosoguanidine; Microscopy, Electron; Phenotype; Rats; Rats, Sprague-Dawley; Staining and Labeling; Vimentin | 1995 |
Sexually differentiated response to choline in choline deficiency and ethionine intoxication.
Topics: Animals; Blood Proteins; Choline; Choline Deficiency; Ethionine; Fatty Liver; Female; Lipoproteins, VLDL; Liver; Male; Protein Biosynthesis; Rats; Rats, Wistar; Sex Factors; Triglycerides | 1995 |
Differentiation of oval cells into duct-like cells in preneoplastic liver of rats placed on a choline-deficient diet supplemented with ethionine.
Topics: Animals; Bile Ducts; Biomarkers; Cell Differentiation; Choline Deficiency; Enzymes; Ethionine; Fetal Proteins; Immunoenzyme Techniques; Liver; Liver Diseases; Male; Precancerous Conditions; Rats; Rats, Wistar; Stem Cells | 1994 |
Deficiency of bile acid transport and synthesis in oval cells from carcinogen-fed rats.
Topics: Animals; Bile Acids and Salts; Biological Transport; Carcinogens; Choline Deficiency; Diet; Epithelium; Ethionine; Liver; Male; Rats; Rats, Sprague-Dawley | 1994 |
Evidence for extraluminal trypsinogen activation in three different models of acute pancreatitis.
Topics: Acute Disease; Animals; Choline Deficiency; Diet; Disease Models, Animal; Duodenum; Enzyme Activation; Ethionine; Female; Ligation; Male; Mice; Necrosis; Oligopeptides; Pancreas; Pancreatic Ducts; Pancreatitis; Rats; Trypsinogen | 1994 |
Expression of L- and M2-pyruvate kinases in proliferating oval cells and cholangiocellular lesions developing in the livers of rats fed a methyl-deficient diet.
Topics: Animals; Antibodies, Monoclonal; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Division; Cholangiocarcinoma; Choline Deficiency; Ethionine; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Necrosis; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Sprague-Dawley | 1994 |
Liver carcinogenesis associated with feeding of ethionine in a choline-free diet: evidence against a role of oval cells in the emergence of hepatocellular carcinoma.
Topics: Animals; Autoradiography; Carcinogens; Choline Deficiency; Diet; Ethionine; Immunohistochemistry; Intermediate Filament Proteins; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Reference Values; Thymidine; Time Factors; Tritium | 1993 |
Phosphatidylcholine peroxidation and liver cancer in mice fed a choline-deficient diet with ethionine.
Topics: Animals; Body Weight; Choline; Choline Deficiency; Diet; Ethionine; Glutathione Transferase; Isoenzymes; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Mice; Organ Size; Phosphatidylcholines; Vitamin E | 1993 |
Early hepatic lesions with marked glandular structures induced in rats by 0.1% ethionine in a choline deficient diet.
Topics: Animals; Choline Deficiency; Ethionine; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Sprague-Dawley | 1993 |
Intracellular Ca2+ dynamics and in vitro secretory response in acute pancreatitis induced by a choline-deficient, ethionine-supplemented diet in mice.
Topics: Acute Disease; Amylases; Animals; Calcium; Choline Deficiency; Ethionine; Female; In Vitro Techniques; Mice; Pancreas; Pancreatitis; Sincalide | 1995 |
Effects of the cholecystokinin receptor antagonist L-364,718 on pancreatitis induced by a deficient in choline and supplemented with ethionine (CDE) diet in the rat.
Topics: Acute Disease; Analysis of Variance; Animals; Benzodiazepinones; Choline Deficiency; Devazepide; Diet; Ethionine; Male; Necrosis; Pancreatitis; Rats; Rats, Wistar; Receptors, Cholecystokinin | 1995 |
Prevention by methionine of enhancement of hepatocarcinogenesis by coadministration of a choline-deficient L-amino acid-defined diet and ethionine in rats.
Topics: Amino Acids; Animals; Carcinogens; Choline Deficiency; Cocarcinogenesis; DNA Damage; Ethionine; Food, Formulated; Gene Expression Regulation; Guanine; Liver; Liver Neoplasms, Experimental; Male; Methionine; Oncogenes; Oxidative Stress; Rats; Rats, Inbred F344; Thiobarbituric Acid Reactive Substances | 1995 |
Transgenic animals demonstrate a role for the IL-1 receptor in regulating IL-1beta gene expression at steady-state and during the systemic stress induced by acute pancreatitis.
Topics: Acute Disease; Animals; Base Sequence; Ceruletide; Choline Deficiency; Cytokines; Diet; DNA Primers; Ethionine; Female; Gene Deletion; Gene Expression; Heterozygote; Homozygote; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Molecular Sequence Data; Pancreatitis; Polymerase Chain Reaction; Receptors, Interleukin-1; RNA, Messenger; Stem Cells | 1996 |
Inhibitory effects of N,N'-diphenyl-p-phenylenediamine on the early stage of the enhanced hepatocarcinogenesis caused by coadministration of ethionine and a choline-deficient L-amino acid-defined diet in rats.
Topics: Amino Acids; Animals; Antioxidants; Choline Deficiency; Cocarcinogenesis; Ethionine; Guanine; Liver Neoplasms, Experimental; Male; Phenylenediamines; Rats; Rats, Inbred F344 | 1996 |
Delineation of antigenic pathways of ethionine-induced liver cancer in the rat.
Topics: alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bile Ducts; Biomarkers; Biomarkers, Tumor; Carcinoma; Cell Differentiation; Cell Division; Cell Lineage; Chemical and Drug Induced Liver Injury; Choline Deficiency; Ethionine; Liver; Liver Diseases; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasm Proteins; Phenotype; Precancerous Conditions; Rats; Rats, Inbred ACI; RNA, Messenger; RNA, Neoplasm; Stem Cells | 1996 |
[Activity and subcellular distribution of lysosomal enzymes in acute pancreatitis induced by CDE diet in mice].
Topics: Acid Phosphatase; Acute Disease; Amylases; Animals; beta-N-Acetylhexosaminidases; Biochemical Phenomena; Biochemistry; Cathepsins; Centrifugation; Choline Deficiency; Diet; Ethionine; Female; Glucuronidase; Lipase; Lysosomes; Mice; Pancreas; Pancreatitis; Subcellular Fractions | 1996 |
The oval-shaped cell as a candidate for a liver stem cell in embryonic, neonatal and precancerous liver: identification based on morphology and immunohistochemical staining for albumin and pyruvate kinase isoenzyme expression.
Topics: Albumins; Animals; Animals, Newborn; Bile Ducts; Choline Deficiency; Ethionine; Food, Formulated; Immunoenzyme Techniques; Liver; Liver Neoplasms; Models, Biological; Neoplastic Stem Cells; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Wistar; Stem Cells | 1997 |
An ETa/ETb endothelin antagonist ameliorates systemic inflammation in a murine model of acute hemorrhagic pancreatitis.
Topics: Acute Disease; Animals; Choline Deficiency; Endothelins; Ethionine; Female; Hemorrhage; Inflammation; Mice; Oligopeptides; Pancreatitis | 1997 |
Possible involvement of 5-HT2 receptor activation in aggravation of diet-induced acute pancreatitis in mice.
Topics: Acute Disease; Animals; Choline Deficiency; Cyproheptadine; Ethionine; Female; Ketanserin; Male; Mice; Mice, Inbred ICR; Pancreatitis; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1997 |
Comparison of liver progenitor cells in human atypical ductular reactions with those seen in experimental models of liver injury.
Topics: Animals; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Cholangiocarcinoma; Choline Deficiency; Cricetinae; Ethionine; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Liver Diseases; Liver Neoplasms; Liver Regeneration; Microscopy, Electron; Necrosis; Propanols; Stem Cells; Time Factors | 1998 |
Pyruvate kinase isoenzyme shift from L-type to M2-type is a late event in hepatocarcinogenesis induced in rats by a choline-deficient/DL-ethionine-supplemented diet.
Topics: Animals; Choline Deficiency; Diet; Ethionine; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Vacuoles | 1998 |
Application of hepatic tolerance tests to the functional reserve assessment in rat models of fatty liver.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Choline Deficiency; Cyclic AMP; Disease Models, Animal; Ethionine; Fatty Liver; Galactosemias; Glucagon; Half-Life; Hepatectomy; Indocyanine Green; Liver; Liver Function Tests; Male; Phospholipids; Rats; Rats, Sprague-Dawley | 1998 |
The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury.
Topics: Acute Disease; Animals; Capillary Permeability; Ceruletide; Choline Deficiency; Death; Ethionine; Female; Intercellular Adhesion Molecule-1; Lung; Male; Mice; Mice, Knockout; Microcirculation; Neutrophils; Pancreatitis; Peroxidase; Pulmonary Circulation | 1999 |
Differentiation status of rat ductal cells and ethionine-induced hepatic carcinomas defined with surface-reactive monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Differentiation; Antigens, Neoplasm; Antigens, Surface; Bile Ducts; Carcinogens; Cell Differentiation; Cell Line; Choline Deficiency; Cocarcinogenesis; Cytoplasm; Epithelial Cells; Ethionine; Female; Hybridomas; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mucus; Phenotype; Rats; Rats, Inbred F344; Stem Cells; Tumor Cells, Cultured | 2000 |
Substance P is a determinant of lethality in diet-induced hemorrhagic pancreatitis in mice.
Topics: Acute Disease; Animals; Choline Deficiency; Death; Diet; Ethionine; Hemorrhage; Inflammation; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neprilysin; Neutrophils; Pancreatitis; Peroxidase; Receptors, Neurokinin-1; Substance P | 2000 |
Adenoviral delivery of human and viral IL-10 in murine sepsis.
Topics: Adenoviridae; Animals; Antimetabolites; Choline Deficiency; Cytokines; Ethionine; Female; Genetic Therapy; Genetic Vectors; Humans; Injections, Intravenous; Interleukin-10; Intubation, Intratracheal; Liver; Lung; Mice; Mice, Inbred C57BL; Pancreatitis; Sepsis; Viral Proteins; Zymosan | 2001 |
A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver.
Topics: Animals; Cell Size; Choline Deficiency; Diet; Ethionine; Immunohistochemistry; Liver; Mice; Mice, Inbred Strains | 2001 |
Enhancement of DL-ethionine-induced liver carcinogenesis in rats fed a choline-devoid diet.
Topics: Animals; Choline; Choline Deficiency; Diet; Ethionine; Liver Neoplasms, Experimental; Male; Rats | 1978 |
[Experimental acute pancreatitis induced in mice by a choline-deficient diet and DL-ethionine].
Topics: Acute Disease; alpha 1-Antitrypsin; Animals; Choline Deficiency; Disease Models, Animal; Enzyme Precursors; Ethionine; Female; Mice; Pancreatitis; Peptide Hydrolases; Phosphatidylcholines; Phospholipids | 1978 |
Protease inhibitors and experimental acute hemorrhagic pancreatitis.
Topics: Acute Disease; Animals; Aprotinin; Chlorophyll; Choline Deficiency; Disease Models, Animal; Ethionine; Female; In Vitro Techniques; Mice; Pancreatic Hormones; Pancreatitis; Protease Inhibitors | 1979 |
Diet-induced pancreatitis in mice: effect of glucagon on mortality and pancreatic function.
Topics: Animals; Choline Deficiency; Diet; Ethionine; Female; Glucagon; Mice; Pancreatitis | 1978 |
Experimental acute pancreatitis in mice. Protective effects of glucagon.
Topics: Amylases; Animals; Choline Deficiency; Ethionine; Female; Glucagon; Mice; Mortality; Pancreas; Pancreatic Juice; Pancreatitis | 1979 |
Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet.
Topics: Acute Disease; Adipose Tissue; Animals; Autopsy; Choline Deficiency; Cytoplasmic Granules; Diet; Disease Models, Animal; Endoplasmic Reticulum; Enzyme Precursors; Ethionine; Female; Golgi Apparatus; Hemorrhage; Islets of Langerhans; Mice; Necrosis; Pancreas; Pancreatic Ducts; Pancreatitis; Vacuoles | 1975 |
Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate.
Topics: Acute Disease; Adenine; Age Factors; Animals; Choline; Choline Deficiency; Diet; Ethionine; Female; Hemorrhage; Male; Methionine; Mice; Necrosis; Pancreatic Diseases; Sex Factors | 1975 |
Effect of protease inhibitor FUT-175 on acute hemorrhagic pancreatitis in mice.
Topics: Acute Disease; Amylases; Animals; Benzamidines; Choline; Choline Deficiency; Diet; Ethionine; Female; Gastrointestinal Hemorrhage; Guanidines; Mice; Pancreatitis; Trypsin; Trypsin Inhibitors | 1992 |
Expression of alpha, mu and pi class glutathione S-transferases in oval and ductal cells in liver of rats placed on a choline-deficient, ethionine-supplemented diet.
Topics: Animals; Choline Deficiency; Diet; Ethionine; Glutathione Transferase; Isoenzymes; Liver; Male; Rats; Rats, Wistar; RNA, Messenger | 1992 |
Role of bacterial infection in diet-induced acute pancreatitis in mice.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Bacterial Infections; Choline; Choline Deficiency; Diet; Digestive System; Ethionine; Female; Mice; Pancreas; Pancreatitis | 1992 |
Effects of antioxidants and free radical scavengers in three different models of acute pancreatitis.
Topics: Acute Disease; Administration, Oral; Allopurinol; Animals; Antioxidants; Catalase; Ceruletide; Choline Deficiency; Deferoxamine; Diet; Dimethyl Sulfoxide; Disease Models, Animal; Ethionine; Female; Free Radical Scavengers; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Male; Mice; Organ Size; Pancreas; Pancreatitis; Rats; Rats, Inbred Strains; Severity of Illness Index; Superoxide Dismutase; Taurocholic Acid | 1992 |
Parathyroid hormone secretion and target organ response in experimental acute pancreatitis.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Acute Disease; Amylases; Animals; Calcium; Chlorides; Choline Deficiency; Ethionine; Hemorrhage; Kidney; Male; Necrosis; Pancreatitis; Parathyroid Hormone; Phosphorus; Rats; Rats, Inbred F344; Spectrophotometry; Weight Loss | 1991 |
Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet.
Topics: Alkaline Phosphatase; Animal Feed; Animals; Cell Division; Choline Deficiency; Ethionine; Food, Fortified; gamma-Glutamyltransferase; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerolphosphate Dehydrogenase; Glycogen Synthase; Immunohistochemistry; Keratins; Liver; Liver Glycogen; Malate Dehydrogenase; Male; Phosphorylases; Rats; Rats, Inbred Strains | 1991 |
Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Azoles; Ceruletide; Choline Deficiency; Diet; Disease Models, Animal; Ethionine; Female; Free Radicals; Isoindoles; Male; Mice; Organ Size; Organoselenium Compounds; Pancreas; Pancreatitis; Selenium | 1991 |
Liver phosphatidylcholine hydroperoxidation provoked by ethionine-containing choline-deficient diet in mice.
Topics: Animals; Body Weight; Choline Deficiency; Ethionine; Fatty Liver; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred Strains; Organ Size; Phosphatidylcholines | 1990 |
Usefulness of rapid production model for pancreatic carcinoma in male hamsters.
Topics: Animals; Carcinoma; Choline Deficiency; Cricetinae; Disease Models, Animal; Ethionine; Gallbladder; Male; Methionine; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1990 |
Monoclonal antibodies recognizing oval cells induced in the liver of rats by N-2-fluorenylacetamide or ethionine in a choline-deficient diet.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens; Cell Differentiation; Choline Deficiency; Ethionine; Female; Fetus; Fluorescent Antibody Technique; gamma-Glutamyltransferase; Hybridomas; Immunization; Liver; Liver Regeneration; Mice; Mice, Inbred BALB C; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Methylation of the alphafetoprotein gene in cell populations isolated from rat livers during carcinogenesis.
Topics: Albumins; alpha-Fetoproteins; Animals; Choline Deficiency; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Ethionine; Gene Expression Regulation; Genes; Liver; Liver Neoplasms, Experimental; Male; Methylation; Polymorphism, Genetic; Rats; Rats, Inbred Strains | 1985 |
Diminished agonist-stimulated inositol trisphosphate generation blocks stimulus-secretion coupling in mouse pancreatic acini during diet-induced experimental pancreatitis.
Topics: Aminoquinolines; Amylases; Animals; Calcimycin; Calcium; Carbachol; Choline Deficiency; Diglycerides; Enzyme Activation; Ethionine; Female; Fluorescence; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; N-Methylscopolamine; Pancreas; Pancreatitis; Protein Kinase C; Scopolamine Derivatives; Sugar Phosphates; Tritium; Type C Phospholipases | 1986 |
Beneficial effects of cholecystokinin-receptor blockade and inhibition of proteolytic enzyme activity in experimental acute hemorrhagic pancreatitis in mice. Evidence for cholecystokinin as a major factor in the development of acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Cholecystokinin; Choline Deficiency; Disease Models, Animal; Ethionine; Female; Gabexate; Guanidines; Hemorrhage; Mice; Pancreas; Pancreatitis; Proglumide; Receptors, Cholecystokinin; Secretin; Time Factors; Trypsin | 1986 |
Role of oxygen-derived free radicals in diet-induced hemorrhagic pancreatitis in mice.
Topics: Acute Disease; Allopurinol; Amylases; Animals; Catalase; Choline Deficiency; Diet; Dimethyl Sulfoxide; Edema; Ethionine; Female; Free Radicals; Hemorrhage; Mice; Necrosis; Oxygen; Pancreatitis | 1987 |
Effects of the cholecystokinin receptor antagonist L-364,718 on experimental pancreatitis in mice.
Topics: Amylases; Animals; Benzodiazepinones; Ceruletide; Cholecystokinin; Choline Deficiency; Devazepide; Ethionine; Male; Mice; Organ Size; Pancreas; Pancreatitis; Receptors, Cholecystokinin | 1989 |
Involvement of cholecystokinin receptors in the adverse effect of glucocorticoids on diet-induced necrotizing pancreatitis.
Topics: Amylases; Animals; Choline Deficiency; Diet; Dose-Response Relationship, Drug; Ethionine; Female; Glucocorticoids; Hydrocortisone; Mice; Mice, Inbred Strains; Necrosis; Pancreas; Pancreatitis; Proglumide; Receptors, Cholecystokinin; Sincalide | 1989 |
Alpha 1-antitrypsin levels predict mortality from ethionine-induced pancreatitis in mice.
Topics: alpha 1-Antitrypsin; Animals; Blood Proteins; Choline Deficiency; Ethionine; Female; Immunodiffusion; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Pancreatitis; Serum Albumin; Sex Factors | 1989 |
[Changes of lipid peroxide (LPO) levels in the development of CDE-diet induced acute pancreatitis in mice: preliminary report].
Topics: Acute Disease; Animals; Choline Deficiency; Diet; Ethionine; Female; Lipid Peroxides; Mice; Mice, Inbred BALB C; Pancreatitis | 1989 |
Failure of a potent cholecystokinin antagonist to protect against diet-induced pancreatitis in mice.
Topics: Animals; Benzodiazepinones; Ceruletide; Cholecystokinin; Choline Deficiency; Devazepide; Diet; Ethionine; Female; Mice; Mice, Inbred Strains; Pancreatitis | 1989 |
Changes in aldehyde dehydrogenase occurring during rat hepatocarcinogenesis induced by ethionine combined with dietary choline deficiency.
Topics: Aldehyde Dehydrogenase; Animals; Choline Deficiency; Enzyme Induction; Ethionine; gamma-Glutamyltransferase; Liver Neoplasms; Liver Neoplasms, Experimental; Male; NAD; NADP; Organ Size; Rats | 1986 |
Rapid production of pancreatic carcinoma by initiation with N-nitroso-bis(2-oxopropyl)amine and repeated augmentation pressure in hamsters.
Topics: Animals; Carcinogens; Carcinoma; Choline Deficiency; Cocarcinogenesis; Cricetinae; Diet; Ethionine; Female; Liver; Mesocricetus; Methionine; Nitrosamines; Pancreatic Neoplasms | 1988 |
[Experimental acute pancreatitis].
Topics: Acute Disease; Animals; Ceruletide; Choline Deficiency; Disease Models, Animal; Duodenum; Enzymes; Ethionine; Humans; Lysosomes; Pancreas; Pancreatic Ducts; Pancreatitis; Trypsin; Trypsinogen | 1986 |
Ethionine in the analysis of the possible separate roles of methionine and choline deficiencies in carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Choline Deficiency; Ethionine; Liver Neoplasms, Experimental; Methionine; Models, Biological | 1986 |
A structural analysis of gap and tight junctions in the rat liver during a dietary treatment that induces oval cell proliferation.
Topics: Animals; Carcinogens; Cell Division; Choline Deficiency; Diet; Ethionine; Freeze Fracturing; Intercellular Junctions; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains | 1986 |
Factors that modify the effects of prostaglandin on diet-induced acute pancreatitis in mice.
Topics: Acute Disease; Animals; Choline Deficiency; Diet; Ethionine; Female; Macrophages; Mice; Mononuclear Phagocyte System; Pancreatitis; Peptide Hydrolases; Prostaglandins E | 1985 |
Light and electron microscopic studies of diet-induced hepatic changes in mice.
Topics: Animals; Choline Deficiency; Cytoplasm; Diet; Ethionine; Female; Lipid Metabolism; Liver; Mice; Microscopy, Electron | 1986 |
Metabolism of ethionine by rats fed a diet deficient in choline.
Topics: Animals; Carbon Radioisotopes; Choline Deficiency; Chromatography, Paper; Diet; Ethionine; Male; Rats; Sulfoxides; Time Factors | 1974 |
Studies on the role of phospholipids in the triglyceride cycle. II. Turnover of plasma phospholipids in ethionine-treated dogs.
Topics: Animals; Choline Deficiency; Diet; Dogs; Ethionine; Female; Injections, Intraperitoneal; Liver; Male; Mathematics; Phosphates; Phospholipids; Phosphorus Isotopes; Triglycerides | 1969 |
Studies on liver phosphatidyl cholines: I. Effects of fatty liver induction on phosphatidyl cholines from liver mitochondria and microsomes.
Topics: Animals; Body Weight; Carbon Tetrachloride; Choline Deficiency; Chromatography, Gas; Chromatography, Thin Layer; Diet; Ethionine; Fatty Acids; Fatty Liver; Female; Liver; Microsomes; Mitochondria, Liver; Oils; Organ Size; Phosphatidylcholines; Phospholipids; Protein Deficiency; Proteins; Rats; Zea mays | 1969 |
Influence of ethionine on choline-deficiency fatty liver.
Topics: Alcohol Oxidoreductases; Animals; Body Weight; Carbon Isotopes; Choline Deficiency; Depression, Chemical; Ethionine; Fasting; Fatty Liver; Female; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Protein Biosynthesis; Proteins; Rats; Time Factors | 1969 |
Effects of cirrhosis and other liver insults on induction of liver tumors by aflatoxin in rats.
Topics: Aflatoxins; Animals; Arachis; Choline Deficiency; Diet; Ethionine; Hepatectomy; Iron; Liver Cirrhosis; Liver Neoplasms; Neoplasms, Experimental; Rats | 1966 |