ethionamide and Euthyroid-Sick-Syndromes

ethionamide has been researched along with Euthyroid-Sick-Syndromes* in 1 studies

Other Studies

1 other study(ies) available for ethionamide and Euthyroid-Sick-Syndromes

Article	Year
Abnormal thyroid function tests in children on ethionamide treatment. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2011, Volume: 15, Issue:9 Ethionamide (ETH) treatment may cause hypothyroidism. Clinical data, serum thyroid stimulating hormone (TSH) and free thyroxine (fT4) levels were retrospectively assessed in 137 children receiving anti-tuberculosis treatment including ETH. Abnormal thyroid function tests (TFTs) were recorded in 79 (58%) children: elevated serum TSH and suppressed fT4 (n = 30), isolated elevated serum TSH (n = 20), isolated low serum fT4 (n = 28) and isolated low TSH (n = 1). The risk for biochemical hypothyroidism was higher for children on regimens including para-aminosalicylic acid and in human immunodeficiency virus infected children. TFT abnormalities are frequent in children on ETH and are mainly due to primary hypothyroidism or euthyroid sick syndrome. Topics: Adolescent; Aminosalicylic Acid; Antitubercular Agents; Child; Child, Preschool; Ethionamide; Euthyroid Sick Syndromes; Female; HIV Infections; Humans; Hypothyroidism; Infant; Male; Retrospective Studies; Thyroid Function Tests; Thyrotropin; Thyroxine; Tuberculosis	2011

Article

Year

Abnormal thyroid function tests in children on ethionamide treatment.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2011, Volume: 15, Issue:9

Ethionamide (ETH) treatment may cause hypothyroidism. Clinical data, serum thyroid stimulating hormone (TSH) and free thyroxine (fT4) levels were retrospectively assessed in 137 children receiving anti-tuberculosis treatment including ETH. Abnormal thyroid function tests (TFTs) were recorded in 79 (58%) children: elevated serum TSH and suppressed fT4 (n = 30), isolated elevated serum TSH (n = 20), isolated low serum fT4 (n = 28) and isolated low TSH (n = 1). The risk for biochemical hypothyroidism was higher for children on regimens including para-aminosalicylic acid and in human immunodeficiency virus infected children. TFT abnormalities are frequent in children on ETH and are mainly due to primary hypothyroidism or euthyroid sick syndrome.

Topics: Adolescent; Aminosalicylic Acid; Antitubercular Agents; Child; Child, Preschool; Ethionamide; Euthyroid Sick Syndromes; Female; HIV Infections; Humans; Hypothyroidism; Infant; Male; Retrospective Studies; Thyroid Function Tests; Thyrotropin; Thyroxine; Tuberculosis

2011