ethinyl estradiol has been researched along with Bile Duct Obstruction, Intrahepatic in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (22.50) | 18.7374 |
| 1990's | 10 (25.00) | 18.2507 |
| 2000's | 5 (12.50) | 29.6817 |
| 2010's | 14 (35.00) | 24.3611 |
| 2020's | 2 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ananthanarayanan, M; Arrese, M; Boyer, JL; Keppler, D; Koeppel, TA; Schlosser, SF; Soroka, CJ; Suchy, FJ; Trauner, M | 1 |
| Cai, H; Chen, X; Kong, WC; Wang, XZ; Xing, MT; Yu, ZX; Zhang, LY; Zou, MZ | 1 |
| Lei, L; Li, Z; Ling, L; Liu, Y; Shao, Y; Xiong, Z | 1 |
| Chen, W; Chen, YH; Gao, L; Gao, XX; Li, L; Liu, ZB; Ma, L; Wang, H; Xu, DX | 1 |
| Xu, M; Zhang, M | 1 |
| Feng, CY; He, WX; Lei, K; Li, XP; Liu, D; Xu, YJ; Yu, ZQ; Zhang, CL | 1 |
| Chen, T; Han, F; Huang, Y; Xu, L; Yang, L; Zhou, T | 1 |
| Lei, K; Liu, D; Xiang, D; Xu, YJ; Yang, JY; Zhang, CL | 1 |
| Duan, Y; Li, B; Qin, H; Wei, M; Wu, X; Wu, Y; Xi, L; Zhang, F; Zhou, Y | 1 |
| Li, H; Shi, Q; Wang, J; Yan, S; Zhao, J | 1 |
| Duan, H; Hua, Y; Li, Y; Luo, C; Mu, D; Qiu, D; Wang, C; Zhan, Y; Zhang, Y; Zhou, K | 1 |
| Deng, C; Gao, B; Huang, G; Wang, X; Xu, T; Zhou, F | 1 |
| Chang, MJ; He, WX; Li, XP; Liu, D; Xu, YJ; Zhang, CL | 1 |
| Shi, Q; Song, Z | 1 |
| Li, LQ; Qi, HB | 1 |
| Leuenberger, N; Pradervand, S; Wahli, W | 1 |
| Qi, HB; Shi, Y | 1 |
| Lin, YG; Lin, YQ; Shi, QY; Yan, S; Zhou, X | 2 |
| Jiang, S; Kong, BH; Ma, KD; Shi, QY; Zhang, XL | 1 |
| Choi, JM; Hong, SS; Jin, HE; Shim, CK | 1 |
| Catania, VA; Ikushiro, S; Luquita, MG; Mottino, AD; Ruiz, ML; Villanueva, SS | 1 |
| Elson, MK; Goodman, M; Knodell, RG; Shafer, RB; Stanley, LN | 1 |
| Obata, T | 1 |
| Goldsmith, MA; Huling, S; Jones, AL | 1 |
| Abe, H; Eguchi, N; Ikejiri, N; Kawaguchi, M; Kuwaki, T; Maeyama, T; Nakao, T; Ninomiya, F; Tanigawa, H | 1 |
| González, MC; Oberhauser, E; Reyes, H; Ribalta, J; Segovia, N | 1 |
| Bouchard, G; Tuchweber, B; Yousef, IM | 1 |
| Buscher, HP; Gerok, W; MacNelly, S; Meder, I | 1 |
| Landmann, L; Rahner, C; Stieger, B | 1 |
| Anderson, JM | 1 |
| Accatino, L; Chianale, J; Koenig, CS; Pizarro, M; Solís, N; Vollrath, V | 1 |
| Moseley, RH | 1 |
| Heufelder, AE; Hofbauer, LC; Jelinek, T; Mrozek-Lasota, A; Schworm, HD; Zimmermann, D | 1 |
| Accatino, L; Koenig, CS; Pizarro, M; Solís, N | 1 |
| Kawaguchi, T; Mori, M; Sakisaka, S; Sata, M; Tanikawa, K | 1 |
| Corenblum, B; Fedorkow, DM; Shaffer, EA | 1 |
| Guerrero, L; Mur, M | 1 |
| Di Padova, C; Frezza, M; Pozzato, G; Tritapepe, R | 1 |
| Höke, H; Jaeschke, H; Krell, H; Metz, J; Pfaff, E | 1 |
40 other study(ies) available for ethinyl estradiol and Bile Duct Obstruction, Intrahepatic
| Article | Year |
|---|---|
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis.
Topics: Animals; ATP-Binding Cassette Transporters; Bile Canaliculi; Blotting, Northern; Blotting, Western; Cholestasis; Cholestasis, Intrahepatic; Common Bile Duct; Down-Regulation; Drug Resistance, Multiple; Ethinyl Estradiol; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation; Lipopolysaccharides; Male; Multidrug Resistance-Associated Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
Activation of natural killer T cells contributes to Th1 bias in the murine liver after 14 d of ethinylestradiol exposure.
Topics: Animals; Cholestasis; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Natural Killer T-Cells; Pregnancy | 2022 |
Resveratrol modulates the gut microbiota of cholestasis in pregnant rats.
Topics: Alanine; Alanine Transaminase; Animals; Aspartic Acid; Bile Acids and Salts; Cholestasis; Cholestasis, Intrahepatic; Dysbiosis; Ethinyl Estradiol; Female; Gastrointestinal Microbiome; Glutamates; Pregnancy; Pregnancy Complications; Rats; Resveratrol; RNA, Ribosomal, 16S; Ursodeoxycholic Acid | 2022 |
Obeticholic Acid Protects against Gestational Cholestasis-Induced Fetal Intrauterine Growth Restriction in Mice.
Topics: Animals; Chenodeoxycholic Acid; Cholestasis, Intrahepatic; Estrogens; Ethinyl Estradiol; Female; Fetal Growth Retardation; Fetus; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Pregnancy; Pregnancy Complications; Signal Transduction | 2019 |
Epigallocatechin-3-gallate ameliorates intrahepatic cholestasis of pregnancy by inhibiting matrix metalloproteinase-2 and matrix metalloproteinase-9.
Topics: Animals; Antioxidants; Catechin; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Pregnancy; Pregnancy Complications; Rats | 2017 |
Protective Effects of Ginsenosides on 17[Formula: see text]-Ethynyelstradiol-Induced Intrahepatic Cholestasis via Anti-Oxidative and Anti-Inflammatory Mechanisms in Rats.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Antioxidants; Cholestasis, Intrahepatic; Cytokines; Dose-Response Relationship, Drug; Ethinyl Estradiol; Ginsenosides; Inflammation Mediators; Male; Phytotherapy; Rats, Wistar; Superoxide Dismutase | 2017 |
Magnesium sulphate can alleviate oxidative stress and reduce inflammatory cytokines in rat placenta of intrahepatic cholestasis of pregnancy model.
Topics: Animals; Bile Acids and Salts; Cholestasis, Intrahepatic; Cytokines; Disease Models, Animal; Ethinyl Estradiol; Female; Magnesium Sulfate; Mitochondria; Oxidative Stress; Placenta; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2018 |
Pharmacokinetic Characteristics of Baicalin in Rats with 17α-ethynyl-estradiol-induced Intrahepatic Cholestasis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Ethinyl Estradiol; Flavonoids; Male; Rats; Rats, Wistar | 2018 |
The ileum-liver Farnesoid X Receptor signaling axis mediates the compensatory mechanism of 17α-ethynylestradiol-induced cholestasis via increasing hepatic biosynthesis of chenodeoxycholic acids in rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Cell Line; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Cholestasis, Intrahepatic; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Ethinyl Estradiol; Humans; Ileum; Liver; Male; Molecular Docking Simulation; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Steroid 12-alpha-Hydroxylase; Up-Regulation | 2018 |
Expression of neuropeptide Y and pro-opiomelanocortin in hypothalamic arcuate nucleus in 17α-ethinyl estradiol-induced intrahepatic cholestasis pregnant rat offspring.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Gene Expression; Neuropeptide Y; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2014 |
The effect of 17α-ethynylestradiol induced intrahepatic cholestasis of pregnancy on placental P-glycoprotein in mice: Implications in the individualized transplacental digoxin treatment for fetal heart failure.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cholestasis, Intrahepatic; Digoxin; Ethinyl Estradiol; Female; Heart Failure; Mice; Placenta; Pregnancy; Pregnancy Complications | 2016 |
Dynamic expression of corticotropin-releasing hormone and urocortin in estrogen induced-cholestasis pregnant rat.
Topics: Animals; Cholestasis, Intrahepatic; Corticotropin-Releasing Hormone; Estrogens; Ethinyl Estradiol; Female; Placenta; Pregnancy; Pregnancy Complications; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Urocortins | 2016 |
Intestinal injury in the rat model of 17α-ethynylestradiol-induced intrahepatic cholestasis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Disease Models, Animal; Ethinyl Estradiol; Gastrointestinal Transit; Intestinal Diseases; Intestines; Liver; Liver Diseases; Male; Noxae; Oxidative Stress; Rats | 2016 |
The Interaction of PPARα and CYP7B1 with ERα, β Impacted the Occurrence and Development of Intrahepatic Cholestasis in Pregnant Rats.
Topics: Animals; Cholestasis, Intrahepatic; Cytochrome P450 Family 7; Estrogen Receptor alpha; Estrogen Receptor beta; Ethinyl Estradiol; Female; Liver; PPAR alpha; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Steroid Hydroxylases | 2017 |
[Expression of aquaporin-8 in the hepatocytes of pregnant rats with intrahepatic cholestasis].
Topics: Animals; Aquaporins; Bile; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Hepatocytes; Immunohistochemistry; Liver; Pregnancy; Pregnancy Complications; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Water | 2008 |
Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice.
Topics: Amino Acid Motifs; Animals; Cholestasis, Intrahepatic; Complement Activation; Cytochrome P450 Family 7; DNA Methylation; Down-Regulation; Enzyme Repression; Ethinyl Estradiol; Female; GA-Binding Protein Transcription Factor; Gene Expression Profiling; Histones; Humans; Ligands; Liver; Male; Mice; Myocardium; Oligonucleotide Array Sequence Analysis; PPAR alpha; Promoter Regions, Genetic; Sex Characteristics; Small Ubiquitin-Related Modifier Proteins; Steroid Hydroxylases; Steroids; Ubiquitination; Up-Regulation | 2009 |
[Effects of intrahepatic cholestasis on morphology of fetal lungs in pregnant rat].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Cholestasis, Intrahepatic; Disease Models, Animal; Ethinyl Estradiol; Female; Fetus; Hepatocytes; Liver; Lung; Microscopy, Electron; Pregnancy; Pregnancy Complications; Progesterone; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley | 2010 |
[Interaction among peroxisome proliferators-activated receptor alpha, cytochrome P450 oxysterol 7α-hydroxylase and estrogen receptor and its association with intrahepatic cholestasis in pregnant rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholestasis, Intrahepatic; Cytochrome P450 Family 7; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Ethinyl Estradiol; Female; Liver; Polymerase Chain Reaction; PPAR alpha; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid Hydroxylases | 2010 |
[Expression of FXR mRNA, PPAR alpha mRNA and bile acid metabolism related genes in intrahepatic cholestasis of pregnant rats].
Topics: Animals; Bile Acids and Salts; Cholestasis, Intrahepatic; Cholesterol 7-alpha-Hydroxylase; Ethinyl Estradiol; Female; PPAR alpha; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger | 2010 |
[Effects of ursodeoxycholic acid on the liver plasma membrane fluidity, hepatic glutathione concentration, hepatic estrogen receptors and progesterone receptors in pregnant rats with ethinylestradiol and progesterone induced intrahepatic cholestasis].
Topics: Animals; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Glutathione; Liver; Membrane Fluidity; Pregnancy; Pregnancy Complications; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Ursodeoxycholic Acid | 2003 |
Altered pharmacokinetics and hepatic uptake of TBuMA in ethynylestradiol-induced cholestasis.
Topics: Animals; Bile Acids and Salts; Cholestasis, Intrahepatic; Disease Models, Animal; Ethinyl Estradiol; Injections, Intravenous; Liver; Male; Models, Biological; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Tritium | 2006 |
Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2.
Topics: Acetaminophen; Animals; Anion Transport Proteins; Antiporters; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Cholestasis, Intrahepatic; Ethinyl Estradiol; Gene Expression; Glucuronosyltransferase; Glutathione; Liver; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organ Size; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; SLC4A Proteins; Spironolactone; Up-Regulation | 2007 |
Effect of cholestasis on hepatic transport of 99mtechnetium p-isopropyl-iminodiacetic acid.
Topics: Alkaline Phosphatase; Animals; Bilirubin; Biological Transport; Cholestasis; Cholestasis, Intrahepatic; Ethinyl Estradiol; Imino Acids; Liver; Male; Organotechnetium Compounds; Rats; Technetium | 1984 |
Intrahepatic cholestasis and hyperbilirubinemia in ethynyl estradiol and chlorpromazine-treated rats.
Topics: Animals; Chlorpromazine; Cholestasis, Intrahepatic; Disease Models, Animal; Ethinyl Estradiol; Female; Hyperbilirubinemia; Liver Function Tests; Male; Rats; Rats, Inbred Strains | 1983 |
Hepatic handling of bile salts and protein in the rat during intrahepatic cholestasis.
Topics: Animals; Autoradiography; Bile Acids and Salts; Biological Transport, Active; Cholestasis, Intrahepatic; Endoplasmic Reticulum; Ethinyl Estradiol; Glycocholic Acid; Golgi Apparatus; Histamine; Horseradish Peroxidase; Iodine Radioisotopes; Liver; Male; Microscopy, Electron; Proteins; Rats; Rats, Inbred Strains; Taurocholic Acid | 1983 |
[Intrahepatic cholestasis caused by oral contraceptives].
Topics: Adult; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Humans; Norethindrone | 1982 |
Sulfobromophthalein clearance tests before and after ethinyl estradiol administration, in women and men with familial history of intrahepatic cholestasis of pregnancy.
Topics: Adult; Cholestasis, Intrahepatic; Ethinyl Estradiol; Female; Humans; Liver Function Tests; Male; Parity; Pregnancy; Pregnancy Complications; Sulfobromophthalein | 1981 |
Influence of oral treatment with ursodeoxycholic and tauroursodeoxycholic acids on estrogen-induced cholestasis in rats: effects on bile formation and liver plasma membranes.
Topics: Administration, Oral; Animals; Bile; Cell Membrane; Cholestasis, Intrahepatic; Ethinyl Estradiol; Fluorescence Polarization; Isomerism; Liver; Male; Membrane Fluidity; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid | 1993 |
Zonal changes of hepatobiliary taurocholate transport in intrahepatic cholestasis induced by 17 alpha-ethinyl estradiol: a histoautoradiographic study in rats.
Topics: Animals; Autoradiography; Bile Ducts; Biological Transport; Cholestasis, Intrahepatic; Ethinyl Estradiol; Image Processing, Computer-Assisted; Liver; Male; Rats; Rats, Wistar; Silver; Taurocholic Acid; Tissue Distribution | 1993 |
Structure-function correlation of tight junctional impairment after intrahepatic and extrahepatic cholestasis in rat liver.
Topics: Animals; Bile; Bile Ducts; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Ethinyl Estradiol; Freeze Fracturing; Horseradish Peroxidase; Ligation; Liver; Male; Microscopy, Electron; Permeability; Rats; Rats, Sprague-Dawley; Tight Junctions | 1996 |
Leaky junctions and cholestasis: a tight correlation.
Topics: Animals; Bile Ducts; Cholestasis; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Ethinyl Estradiol; Ligation; Liver; Permeability; Rats; Tight Junctions | 1996 |
Modulation of hepatic content and biliary excretion of P-glycoproteins in hepatocellular and obstructive cholestasis in the rat.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Cell Membrane; Cholestasis; Cholestasis, Intrahepatic; Ethinyl Estradiol; Gene Expression; Genes, MDR; Immunohistochemistry; Liver; Male; Rats; Rats, Wistar | 1996 |
A molecular basis for jaundice in intrahepatic and extrahepatic cholestasis.
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Ducts; Blotting, Northern; Blotting, Western; Carrier Proteins; Cholestasis; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Down-Regulation; Estradiol Congeners; Ethinyl Estradiol; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation; Jaundice; Rats; RNA, Messenger | 1997 |
[Endocrinologic and metabolic complications of Alagille syndrome].
Topics: Adult; Alagille Syndrome; Cholestasis, Intrahepatic; Contraceptives, Oral, Hormonal; Desogestrel; Dwarfism, Pituitary; Ethinyl Estradiol; Female; Humans; Rickets; Spinocerebellar Degenerations; Vitamin D Deficiency | 1997 |
Effects of diosgenin, a plant-derived steroid, on bile secretion and hepatocellular cholestasis induced by estrogens in the rat.
Topics: Animals; Bile; Cholestasis, Intrahepatic; Diosgenin; Estradiol; Estrogens; Ethinyl Estradiol; Histocytochemistry; Liver; Male; Microscopy, Electron; Plant Extracts; Rats; Rats, Sprague-Dawley; Steroids | 1998 |
Different lobular distributions of altered hepatocyte tight junctions in rat models of intrahepatic and extrahepatic cholestasis.
Topics: Animals; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Estradiol Congeners; Ethinyl Estradiol; Immunoblotting; Immunohistochemistry; Ligation; Liver; Male; Microscopy, Confocal; Rats; Rats, Sprague-Dawley; Tight Junctions; Time Factors | 1999 |
Cholestasis induced by oestrogen after liver transplantation.
Topics: Adult; Cholestasis, Intrahepatic; Dose-Response Relationship, Drug; Ethinyl Estradiol; Female; Humans; Liver Transplantation; Menorrhagia; Postoperative Complications | 1989 |
[Intrahepatic cholestasis caused by oral contraceptives with early onset].
Topics: Adult; Cholestasis, Intrahepatic; Contraceptives, Oral, Hormonal; Ethinyl Estradiol; Female; Humans | 1988 |
Prevention of S-adenosylmethionine of estrogen-induced hepatobiliary toxicity in susceptible women.
Topics: Adult; Bile; Cholestasis, Intrahepatic; Disease Susceptibility; Drug Evaluation; Ethinyl Estradiol; Female; Humans; Lipid Metabolism; Liver Function Tests; S-Adenosylmethionine | 1988 |
Drug-induced intrahepatic cholestasis: characterization of different pathomechanisms.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Cholestasis, Intrahepatic; Estradiol; Ethinyl Estradiol; In Vitro Techniques; Liver; Microscopy, Electron; Perfusion; Rats; Rats, Inbred Strains | 1987 |