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ethidium and Zellweger Syndrome

ethidium has been researched along with Zellweger Syndrome in 1 studies

Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.

Zellweger Syndrome: An autosomal recessive disorder due to defects in PEROXISOME biogenesis which involves more than 13 genes encoding peroxin proteins of the peroxisomal membrane and matrix. Zellweger syndrome is typically seen in the neonatal period with features such as dysmorphic skull; MUSCLE HYPOTONIA; SENSORINEURAL HEARING LOSS; visual compromise; SEIZURES; progressive degeneration of the KIDNEYS and the LIVER. Zellweger-like syndrome refers to phenotypes resembling the neonatal Zellweger syndrome but seen in children or adults with apparently intact peroxisome biogenesis.

Research Excerpts

ExcerptRelevanceReference
" Analysing the P12 dose-response in Zellweger fibroblasts, we observed that at high doses (1-2 microM), more than 75% of the cells died after 24 h."1.30Evidence that photodynamic stress kills Zellweger fibroblasts by a nonapoptotic mechanism. ( Calzolari, E; Cavazzoni, M; Griffoni, C; Spisni, E; Tomasi, V, 1998)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spisni, E1
Cavazzoni, M1
Griffoni, C1
Calzolari, E1
Tomasi, V1

Other Studies

1 other study available for ethidium and Zellweger Syndrome

ArticleYear
Evidence that photodynamic stress kills Zellweger fibroblasts by a nonapoptotic mechanism.
    Biochimica et biophysica acta, 1998, Mar-12, Volume: 1402, Issue:1

    Topics: Apoptosis; Catalase; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Ethidiu

1998