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ethidium and Neoplasms

ethidium has been researched along with Neoplasms in 17 studies

Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" In contrast, sequential tumor biopsies from a melanoma patient on methotrexate-citrovorum factor rescue therapy showed no changes."3.65Flow microfluorometric patterns of human bone marrow and tumor cells in response to cancer chemotherapy. ( Frei, E; Krishan, A; Paika, KD; Pitman, SW; Smith, DC; Tattersall, HN, 1976)
"The mouse Ehrlich ascites tumor cell line (EAT) and a human small-cell carcinoma line (GLC4) were incubated for 4 hr at 37 degrees C, with the cross-linking agent cis-diamino-dichloro platinum (cDDP)."1.27Detection of DNA cross-links in tumor cells with the ethidium bromide fluorescence assay. ( de Jong, S; de Vries, EG; Mulder, NH; Timmer-Bosscha, H; Zijlstra, JG, 1986)
"Ethidium bromide was added to cultured human leukemic bone marrow and solid tumor cells to evaluate its inhibitory effect on mitotic chromosome condensation and its possible application to high-resolution banding analysis."1.27Application of ethidium bromide for high-resolution banding analysis of chromosomes from human malignant cells. ( Testa, JR; Tomiyasu, T, 1988)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's2 (11.76)18.2507
2000's1 (5.88)29.6817
2010's2 (11.76)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Alsaeedi, MS1
Babgi, BA1
Hussien, MA1
Abdellattif, MH1
Humphrey, MG1
Russ, V1
Günther, M1
Halama, A1
Ogris, M1
Wagner, E1
Huang, QD1
Zhong, GX1
Zhang, Y1
Ren, J1
Fu, Y1
Zhang, J1
Zhu, W1
Yu, XQ1
Tabassum, S1
Afzal, M1
Arjmand, F1
KANDASWAMY, TS1
HENDERSON, JF1
Barlogie, B1
Drewinko, B1
Schumann, J1
Göhde, W1
Dosik, G1
Latreille, J1
Johnston, DA1
Freireich, EJ1
Léonce, S1
Perez, V1
Casabianca-Pignede, MR1
Anstett, M1
Bisagni, E1
Pierré, A1
Atassi, G1
Naidoo, R1
Chetty, R1
Wilkie, D1
Egilsson, V1
Evans, IH1
Krishan, A1
Pitman, SW1
Tattersall, HN1
Paika, KD1
Smith, DC1
Frei, E1
De Duve, C1
Hoberman, HD1
Petersen, SE1
Nomura, K1
de Jong, S1
Zijlstra, JG1
Timmer-Bosscha, H1
Mulder, NH1
de Vries, EG1
Tomiyasu, T1
Testa, JR1
Wakabayashi, A1
Shiotsuki, K1
Shirouzu, G1
Tokutomi, Y1
Yatsuka, K1
Yokoyama, M1

Reviews

2 reviews available for ethidium and Neoplasms

ArticleYear
The application of microsatellites in molecular pathology.
    Pathology oncology research : POR, 1998, Volume: 4, Issue:4

    Topics: Autoradiography; DNA Primers; Ethidium; Fluorometry; Genetic Diseases, Inborn; Genetic Markers; Huma

1998
Is there a role for mitochondrial genes in carcinogenesis?
    Cancer research, 1975, Volume: 35, Issue:11 Pt. 2

    Topics: Animals; Cytochromes; DNA, Mitochondrial; Ethidium; Extrachromosomal Inheritance; Humans; L Cells; L

1975

Other Studies

15 other studies available for ethidium and Neoplasms

ArticleYear
DNA-Binding and Anticancer Activity of Binuclear Gold(I) Alkynyl Complexes with a Phenanthrenyl Bridging Ligand.
    Molecules (Basel, Switzerland), 2020, Feb-25, Volume: 25, Issue:5

    Topics: Alkynes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; DNA; D

2020
Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Dec-08, Volume: 132, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Survival; Dendrimers; Electricity; Erythrocytes; Ethidium; Gene Expr

2008
Cyclen-based cationic lipids for highly efficient gene delivery towards tumor cells.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Cations; Cell Death; Cell Line, Tumor; Cyclams; DNA; Electrophoretic Mobility Shift Assay; Ethidium;

2011
New heterobimetallic Cu(II)-Sn2(IV) complex as potential topoisomerase I inhibitor: in vitro DNA binding, cleavage and cytotoxicity against human cancer cell lines.
    Journal of photochemistry and photobiology. B, Biology, 2012, Oct-03, Volume: 115

    Topics: Antineoplastic Agents; Base Sequence; Cell Line, Tumor; Copper; DNA; DNA Cleavage; DNA Topoisomerase

2012
Inhibition of ascites tumour growth by the trypanocide, ethidium bromide, in combination with azaserine.
    Nature, 1962, Jul-07, Volume: 195

    Topics: Antineoplastic Agents; Ascites; Azaserine; Ethidium; Humans; Neoplasms; Quinolines; Trypanocidal Age

1962
Cellular DNA content as a marker of neoplasia in man.
    The American journal of medicine, 1980, Volume: 69, Issue:2

    Topics: Adult; Age Factors; Aged; Aneuploidy; Cell Count; Cell Transformation, Neoplastic; Cytogenetics; DNA

1980
In vitro cytotoxicity of S16020-2, a new olivacine derivative.
    Investigational new drugs, 1996, Volume: 14, Issue:2

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Division; DNA Topoi

1996
Letter: Mitochondria in oncogenesis.
    Lancet (London, England), 1975, Mar-22, Volume: 1, Issue:7908

    Topics: Acriflavine; Animals; Bromides; Carcinogens; Cell Membrane; Cell Transformation, Neoplastic; Daunoru

1975
Flow microfluorometric patterns of human bone marrow and tumor cells in response to cancer chemotherapy.
    Cancer research, 1976, Volume: 36, Issue:10

    Topics: Antineoplastic Agents; Bone Marrow Cells; Cell Division; Cytarabine; Ethidium; Fluorometry; Humans;

1976
[Cellular pathology].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1976, Volume: 38, Issue:5

    Topics: Acid Phosphatase; Animals; Arteriosclerosis; Cholesterol; Daunorubicin; DNA; Ethidium; Heart; Humans

1976
Accuracy and reliability of flow cytometric DNA analysis using a simple, one-step ethidium bromide staining protocol.
    Cytometry, 1986, Volume: 7, Issue:4

    Topics: Animals; DNA; Ethidium; Female; Flow Cytometry; Humans; Liver; Lymphocytes; Male; Mice; Neoplasms; P

1986
[Clinical application of flow cytometric analysis to predict results of radiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7

    Topics: DNA Damage; Ethidium; Flow Cytometry; HeLa Cells; Humans; Neoplasms; Radiation Tolerance

1989
Detection of DNA cross-links in tumor cells with the ethidium bromide fluorescence assay.
    International journal of cancer, 1986, Apr-15, Volume: 37, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Small Cell; Cells, Cultured; DNA, Neoplasm; Ethidium;

1986
Application of ethidium bromide for high-resolution banding analysis of chromosomes from human malignant cells.
    Stain technology, 1988, Volume: 63, Issue:2

    Topics: Chromosome Banding; Chromosomes, Human, Pair 2; Ethidium; Humans; Leukemia; Mitosis; Neoplasms

1988
[The application of the automated fluorometric system to the measurement of lymphocyte transformation with ethidium bromide].
    Rinsho byori. The Japanese journal of clinical pathology, 1985, Volume: 33, Issue:3

    Topics: Cells, Cultured; Ethidium; Fluorometry; Humans; Lymphocyte Activation; Neoplasms

1985