Page last updated: 2024-10-28

ethidium and Multiple Myeloma

ethidium has been researched along with Multiple Myeloma in 7 studies

Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.

Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"RPMI 8226 multiple myeloma cells expressed P2X7 mRNA and protein, as well as P2X1, P2X4 and P2X5 mRNA."1.36P2X7 receptor activation induces cell death and CD23 shedding in human RPMI 8226 multiple myeloma cells. ( Farrell, AW; Gadeock, S; Jalilian, I; Pupovac, A; Ranson, M; Sluyter, R; Wang, B, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Farrell, AW1
Gadeock, S1
Pupovac, A1
Wang, B1
Jalilian, I1
Ranson, M1
Sluyter, R1
Berezkina, EV1
Lipskaia, LA1
Grinchuk, TM1
Kovaleva, ZV1
Sorokina, EA1
Vasiukhin, VI1
Ignatova, TN4
Davtian, TK3
Meliksetian, MB3
Aleksanian, IuT3
Ivanova, IV1
Solage, A1
Laskov, R1
Kimmel, CB1
Wang, CZ1

Other Studies

7 other studies available for ethidium and Multiple Myeloma

ArticleYear
P2X7 receptor activation induces cell death and CD23 shedding in human RPMI 8226 multiple myeloma cells.
    Biochimica et biophysica acta, 2010, Volume: 1800, Issue:11

    Topics: Apoptosis; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Ethidium; Flow Cytometry; Fluoresce

2010
[The isolation and genetic characteristics of the new cell line of mouse myeloma spEBR-5 selected for ethidium bromide resistance and characterized by multiple drug resistance].
    Tsitologiia, 1994, Volume: 36, Issue:7

    Topics: Animals; Cell Separation; Chromosomes; DNA, Neoplasm; Drug Resistance, Multiple; Electrophoresis, Ag

1994
[The adaptive response of B cells to the action of cytotoxic preparations in culture. II. Immunoglobulin interaction with adriamycin and ethidium bromide].
    Tsitologiia, 1993, Volume: 35, Issue:6-7

    Topics: Adaptation, Physiological; Affinity Labels; Animals; B-Lymphocytes; Binding, Competitive; Cell Line;

1993
[The adaptive response of B cells to the action of cytotoxic preparations in culture. III. The possible mechanism of the action of adriamycin on immunoglobin synthesis by the cells of murine myeloma].
    Tsitologiia, 1993, Volume: 35, Issue:6-7

    Topics: 2,2'-Dipyridyl; Adaptation, Physiological; Animals; Cell Line; Cysteine; Dose-Response Relationship,

1993
[The adaptive response of B cells in culture to the action of cytotoxic agents. I. The stimulation of immunoglobulin synthesis and secretion by myeloma cells, hybridomas and human lymphocytes under the influence of adriamycin and ethidium bromide].
    Tsitologiia, 1993, Volume: 35, Issue:4

    Topics: Adaptation, Physiological; Animals; Antibody-Producing Cells; B-Lymphocytes; Cells, Cultured; Doxoru

1993
Characterization of cytoplasmic DNA of mouse-myeloma cells.
    European journal of biochemistry, 1975, Dec-01, Volume: 60, Issue:1

    Topics: Animals; Cell Line; Cytoplasm; DNA, Circular; DNA, Neoplasm; Ethidium; Mice; Mice, Inbred BALB C; Mu

1975
Cytoplasmic RNA in immunologlobulin-secreting myeloma tumor cells. I. Identification and characteristics of a class of heterogeneous RNA.
    Biochimica et biophysica acta, 1972, May-29, Volume: 269, Issue:3

    Topics: Animals; Carbon Isotopes; Cell Fractionation; Cell Line; Cytoplasm; Dactinomycin; Electrophoresis; E

1972