ethidium has been researched along with Melanoma in 14 studies
Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relationship between DNA crosslinks and cell death as a result of exposure to melphalan (MLN) was studied in the F1 variant of B16 melanoma cells." | 7.67 | Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells. ( Garcia, ST; McQuillan, A; Panasci, L, 1988) |
| " Fluorescence microscopy using AO/EB (acridine orange/ethidium bromide) staining indicated that KA can induce both apoptosis and necrosis in HL-60 cell cultures, which corroborate the findings with MTT." | 3.75 | Kauren-19-oic acid induces DNA damage followed by apoptosis in human leukemia cells. ( Bezerra, DP; Câmara, CA; Cavalcanti, BC; Costa-Lotufo, LV; Lima, MA; Magalhães, HI; Moraes, MO; Pessoa, C; Rao, VS; Silveira, ER, 2009) |
| "The relationship between DNA crosslinks and cell death as a result of exposure to melphalan (MLN) was studied in the F1 variant of B16 melanoma cells." | 3.67 | Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells. ( Garcia, ST; McQuillan, A; Panasci, L, 1988) |
| " In contrast, sequential tumor biopsies from a melanoma patient on methotrexate-citrovorum factor rescue therapy showed no changes." | 3.65 | Flow microfluorometric patterns of human bone marrow and tumor cells in response to cancer chemotherapy. ( Frei, E; Krishan, A; Paika, KD; Pitman, SW; Smith, DC; Tattersall, HN, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalcanti, BC | 1 |
| Bezerra, DP | 1 |
| Magalhães, HI | 1 |
| Moraes, MO | 1 |
| Lima, MA | 1 |
| Silveira, ER | 1 |
| Câmara, CA | 1 |
| Rao, VS | 1 |
| Pessoa, C | 1 |
| Costa-Lotufo, LV | 1 |
| Eskandarpour, M | 1 |
| Kiaii, S | 1 |
| Zhu, C | 1 |
| Castro, J | 1 |
| Sakko, AJ | 1 |
| Hansson, J | 1 |
| Ghelelovitch, S | 1 |
| Lessin, SR | 1 |
| Abraham, SR | 1 |
| Nicolini, C | 1 |
| Kuhlmann, KF | 1 |
| Mosher, CW | 1 |
| Poot, M | 1 |
| Hiller, KH | 1 |
| Heimpel, S | 1 |
| Schuster, A | 1 |
| Köhler, J | 1 |
| Hoehn, H | 1 |
| Lucas, P | 1 |
| Milroy, DA | 1 |
| Thomas, BJ | 1 |
| Moss, SH | 1 |
| Pouton, CW | 1 |
| Krishan, A | 1 |
| Pitman, SW | 1 |
| Tattersall, HN | 1 |
| Paika, KD | 1 |
| Smith, DC | 1 |
| Frei, E | 1 |
| Pavelic, K | 1 |
| Beerman, TA | 1 |
| Bernacki, RJ | 1 |
| Bucana, C | 1 |
| Saiki, I | 1 |
| Nayar, R | 1 |
| Garcia, ST | 1 |
| McQuillan, A | 1 |
| Panasci, L | 1 |
| Birkmayer, GD | 3 |
| Miller, F | 2 |
| Balda, BR | 3 |
14 other studies available for ethidium and Melanoma
| Article | Year |
|---|---|
Kauren-19-oic acid induces DNA damage followed by apoptosis in human leukemia cells.
Topics: Acridine Orange; Apoptosis; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Comet Assay; Di | 2009 |
Suppression of oncogenic NRAS by RNA interference induces apoptosis of human melanoma cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Codon; Coloring Agents; Cyclin D1; Down-Regulation; | 2005 |
Effect of the inhibition of nucleic acids and protein synthesis upon the development of melanotic tumors in Drosophila.
Topics: Animals; Cell Division; Chloramphenicol; Cycloheximide; Dactinomycin; Drosophila melanogaster; Ethid | 1983 |
Biophysical identification and sorting of high metastatic variants from B16 melanoma tumor.
Topics: Animals; Cell Line; Cell Membrane; Cell Separation; DNA, Neoplasm; Ethidium; Flow Cytometry; Fluores | 1982 |
New dimeric analogues of ethidium; synthesis, interaction with DNA, and antitumor activity.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; DNA; DNA, Neoplasm; Ethidium; Leukemi | 1981 |
Heterogeneity of bromodeoxyuridine sensitivity of cultured cells from melanoma metastases.
Topics: Bisbenzimidazole; Bromodeoxyuridine; Cell Division; Ethidium; Flow Cytometry; G2 Phase; Genetic Hete | 1995 |
Pharmaceutical and biological properties of poly(amino acid)/DNA polyplexes.
Topics: Amino Acids; Animals; Cations; DNA; Ethidium; Gene Transfer Techniques; Melanoma; Mice; Polymers; Tr | 1999 |
Flow microfluorometric patterns of human bone marrow and tumor cells in response to cancer chemotherapy.
Topics: Antineoplastic Agents; Bone Marrow Cells; Cell Division; Cytarabine; Ethidium; Fluorometry; Humans; | 1976 |
An evaluation of the effects of combination chemotherapy in vitro using DNA-reactive agents.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cisplatin; Colonic Neoplasms; DNA; Doxorubicin | 1985 |
Uptake and accumulation of the vital dye hydroethidine in neoplastic cells.
Topics: Animals; Cell Line; Cytophotometry; Ethidium; Fibrosarcoma; Flow Cytometry; Fluorescent Dyes; Humans | 1986 |
Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells.
Topics: Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Ethidium; Fluorescence; Humans; Melanoma; Melph | 1988 |
Inhibition of high molecular weight RNA synthesis in a hamster melanoma by ethidium bromide in vivo.
Topics: Animals; Antiviral Agents; Cell Fractionation; Centrifugation, Density Gradient; Cricetinae; DNA Nuc | 1972 |
Drug effects in melanoma: tumor-specific interactions of proflavine and ethidiumbromide.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Centrifugation, Density | 1973 |
Oncorna-viral information in human melanoma.
Topics: Brain Neoplasms; Dactinomycin; DNA Nucleotidyltransferases; Ethidium; Humans; Lymphatic Metastasis; | 1974 |