ethidium has been researched along with MELAS Syndrome in 2 studies
Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "His mother also had IDDM, but no A3243G mutation could be detected in her blood or transformed lymphoblasts using the same PCR technique." | 1.30 | Diabetes and mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS): radiolabeled polymerase chain reaction is necessary for accurate detection of low percentages of mutation. ( Haas, RH; Hua, XY; Kennaway, NG; Liu, D; Marsden, DL; Ngo, KY; Smith, ML, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abu-Amero, KK | 1 |
| Bosley, TM | 1 |
| Bohlega, S | 1 |
| Hansen, E | 1 |
| Smith, ML | 1 |
| Hua, XY | 1 |
| Marsden, DL | 1 |
| Liu, D | 1 |
| Kennaway, NG | 1 |
| Ngo, KY | 1 |
| Haas, RH | 1 |
2 other studies available for ethidium and MELAS Syndrome
| Article | Year |
|---|---|
Mitochondrial T9957C mutation in association with NAION and seizures but not MELAS.
Topics: Case-Control Studies; DNA, Mitochondrial; Ethidium; Flow Cytometry; Humans; Magnetic Resonance Spect | 2005 |
Diabetes and mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS): radiolabeled polymerase chain reaction is necessary for accurate detection of low percentages of mutation.
Topics: Adult; Autoradiography; Child; Diabetes Mellitus, Type 1; DNA, Mitochondrial; Electron Transport; Et | 1997 |