ethidium has been researched along with Lupus Erythematosus, Systemic in 8 studies
Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Purified IgG from patients with Systemic Lupus Erythematosus (SLE) containing anti-dsDNA antibodies competes with EB for binding to DNA resulting in a decrease in fluorescence." | 1.26 | The binding of anti-DNA antibodies as measured fluorometrically by ethidium bromide. ( Fritzler, MJ; Shepherd, JD; van de Sande, JH; Watson, JI, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyashita, H | 1 |
| Chikazawa, M | 1 |
| Otaki, N | 1 |
| Hioki, Y | 1 |
| Shimozu, Y | 1 |
| Nakashima, F | 1 |
| Shibata, T | 1 |
| Hagihara, Y | 1 |
| Maruyama, S | 1 |
| Matsumi, N | 1 |
| Uchida, K | 1 |
| Gilliam, AC | 1 |
| Lang, D | 1 |
| LoSpalluto, JJ | 1 |
| Shepherd, JD | 1 |
| Fritzler, MJ | 1 |
| Watson, JI | 1 |
| van de Sande, JH | 1 |
| Okudaira, K | 1 |
| Nakai, H | 1 |
| Hayakawa, T | 1 |
| Kashiwado, T | 1 |
| Tanimoto, K | 1 |
| Horiuchi, Y | 1 |
| Juji, T | 1 |
| Steinman, CR | 1 |
| Davis, P | 1 |
| Burrington, M | 1 |
| Russell, AS | 1 |
| Morgan, AR | 1 |
| Tsay, GJ | 1 |
| Chan, EK | 1 |
| Peebles, CL | 1 |
| Pollard, KM | 1 |
| Tan, EM | 1 |
| Riboldi, P | 1 |
| Asero, R | 1 |
8 other studies available for ethidium and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Lysine pyrrolation is a naturally-occurring covalent modification involved in the production of DNA mimic proteins.
Topics: Amino Acid Sequence; Animals; Benzothiazoles; Diamines; DNA; Ethidium; Female; Fluorescent Dyes; Hum | 2014 |
Antibodies to double-stranded DNA: purification and characterization of binding specificities.
Topics: Animals; Antibodies; Binding Sites, Antibody; Binding, Competitive; Buffers; Cattle; Chromatography, | 1980 |
The binding of anti-DNA antibodies as measured fluorometrically by ethidium bromide.
Topics: Antibodies, Antinuclear; Binding Sites, Antibody; Binding, Competitive; DNA; Epitopes; Ethidium; Hum | 1978 |
Detection of antilymphocyte antibody with two-color method in systemic lupus erythematosus and its heterogeneous specificities against human T-cell subsets.
Topics: Antibody Specificity; Autoantibodies; Cytotoxicity Tests, Immunologic; Ethidium; Fluoresceins; Human | 1979 |
Quantitation of submicrogram concentrations of DNA by a modified Laurell electrophoresis method.
Topics: Animals; Cattle; Deoxyribonucleases; DNA; Ethidium; Fluorescent Antibody Technique; Guanidines; Huma | 1979 |
Analysis of DNA structure by hydroxyapatite columns and ethidium bromide fluorescence techniques. A comparative study and effect on DNA binding.
Topics: Antibodies; Antibody Specificity; Chromatography; DNA; DNA Helicases; DNA Replication; DNA, Single-S | 1978 |
An immunoassay differentiating sera with antibodies to Sm alone, antibodies to Sm/RNP complex, and antibodies to RNP alone.
Topics: Autoantibodies; Autoantigens; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Enzyme | 1987 |
Ethidium bromide in the detection of antibodies to DNA and of circulating DNA by two-stage counterimmunoelectrophoresis.
Topics: Autoantibodies; Counterimmunoelectrophoresis; DNA; Ethidium; Humans; Lupus Erythematosus, Systemic | 1985 |