ethidium has been researched along with Leukemia in 10 studies
Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fluorescence microscopy using AO/EB (acridine orange/ethidium bromide) staining indicated that KA can induce both apoptosis and necrosis in HL-60 cell cultures, which corroborate the findings with MTT." | 3.75 | Kauren-19-oic acid induces DNA damage followed by apoptosis in human leukemia cells. ( Bezerra, DP; Câmara, CA; Cavalcanti, BC; Costa-Lotufo, LV; Lima, MA; Magalhães, HI; Moraes, MO; Pessoa, C; Rao, VS; Silveira, ER, 2009) |
| "The superhelical properties of nuclear DNA from malignant cells of human origin (leukemic cell lines Reh and D-562, mesothelioma cell line, and peripheral blood monocytes from acute monocytic leukemia) were investigated in neutral sucrose gradients with ethidium bromide." | 3.66 | Winding anomalies in nuclear DNA from malignant cells. I. Experimental evidence. ( Arnold, W; Hartwig, M; Karsten, U; Kopp, J; Körner, IJ; Matthes, E; Milleck, J; Raderecht, C; Schleusner, A, 1982) |
| "Ethidium bromide was added to cultured human leukemic bone marrow and solid tumor cells to evaluate its inhibitory effect on mitotic chromosome condensation and its possible application to high-resolution banding analysis." | 1.27 | Application of ethidium bromide for high-resolution banding analysis of chromosomes from human malignant cells. ( Testa, JR; Tomiyasu, T, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mansouri-Torshizi, H | 1 |
| Zareian-Jahromi, S | 1 |
| Abdi, K | 1 |
| Saeidifar, M | 1 |
| Almajhdi, FN | 1 |
| Ali, G | 1 |
| Cavalcanti, BC | 1 |
| Bezerra, DP | 1 |
| Magalhães, HI | 1 |
| Moraes, MO | 1 |
| Lima, MA | 1 |
| Silveira, ER | 1 |
| Câmara, CA | 1 |
| Rao, VS | 1 |
| Pessoa, C | 1 |
| Costa-Lotufo, LV | 1 |
| Gianni, AM | 1 |
| Dalla-Favera, R | 1 |
| Polli, E | 1 |
| Zafar, MN | 1 |
| O'Brien, M | 1 |
| Catovsky, D | 1 |
| Hartwig, M | 1 |
| Matthes, E | 1 |
| Körner, IJ | 1 |
| Kopp, J | 1 |
| Arnold, W | 1 |
| Milleck, J | 1 |
| Karsten, U | 1 |
| Raderecht, C | 1 |
| Schleusner, A | 1 |
| Hoberman, HD | 1 |
| Paponov, VD | 1 |
| Rad'ko, SP | 1 |
| Shcheglova, EG | 1 |
| Tomiyasu, T | 1 |
| Testa, JR | 1 |
| Böhmer, RM | 1 |
1 review available for ethidium and Leukemia
| Article | Year |
|---|---|
Is there a role for mitochondrial genes in carcinogenesis?
Topics: Animals; Cytochromes; DNA, Mitochondrial; Ethidium; Extrachromosomal Inheritance; Humans; L Cells; L | 1975 |
9 other studies available for ethidium and Leukemia
| Article | Year |
|---|---|
Nonionic but water soluble, [Glycine-Pd-Alanine] and [Glycine-Pd-Valine] complexes. Their synthesis, characterization, antitumor activities and rich DNA/HSA interaction studies.
Topics: Alanine; Antineoplastic Agents; Binding Sites; Circular Dichroism; Cisplatin; Coordination Complexes | 2019 |
Report on influenza A and B viruses: their coinfection in a Saudi leukemia patient.
Topics: Alphainfluenzavirus; Betainfluenzavirus; Coinfection; Ethidium; Female; Humans; Infant; Influenza, H | 2013 |
Kauren-19-oic acid induces DNA damage followed by apoptosis in human leukemia cells.
Topics: Acridine Orange; Apoptosis; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Comet Assay; Di | 2009 |
Restriction enzyme analysis of human leukemic mitochondrial DNA.
Topics: DNA Restriction Enzymes; DNA, Mitochondrial; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Eth | 1980 |
Similarities in mitochondrial ultrastructure of leukemic cells and ethidium-bromide-treated normal cells.
Topics: Ethidium; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Microscopy, Electron; Mito | 1982 |
Winding anomalies in nuclear DNA from malignant cells. I. Experimental evidence.
Topics: Cell Line; Cell Nucleus; DNA, Neoplasm; DNA, Superhelical; Ethidium; Humans; Leukemia; Lymphocytes; | 1982 |
[Topological DNA heterogeneity in the nucleoids of human leukocytes].
Topics: Cell Nucleus; DNA, Superhelical; Ethidium; Genes; Humans; Leukemia; Leukocytes; Viscosity | 1988 |
Application of ethidium bromide for high-resolution banding analysis of chromosomes from human malignant cells.
Topics: Chromosome Banding; Chromosomes, Human, Pair 2; Ethidium; Humans; Leukemia; Mitosis; Neoplasms | 1988 |
Flow cytometric detection of a two-step cell death induced by hyperthermia.
Topics: Acridine Orange; Cell Line; Cell Survival; Ethidium; Flow Cytometry; Hot Temperature; Humans; Kineti | 1985 |