ethidium has been researched along with Huntington Disease in 2 studies
Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The expanded CAG repeat in the Huntington's disease (HD) gene may display tissue-specific variability (e." | 1.35 | DNA instability in replicating Huntington's disease lymphoblasts. ( Cannella, M; Frati, L; Li, GM; Maglione, V; Martino, T; Ragona, G; Squitieri, F, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cannella, M | 1 |
| Maglione, V | 1 |
| Martino, T | 1 |
| Ragona, G | 1 |
| Frati, L | 1 |
| Li, GM | 1 |
| Squitieri, F | 1 |
| Valdes, JM | 1 |
| Tagle, DA | 1 |
| Elmer, LW | 1 |
| Collins, FS | 1 |
2 other studies available for ethidium and Huntington Disease
| Article | Year |
|---|---|
DNA instability in replicating Huntington's disease lymphoblasts.
Topics: Cell Division; Cell Line; Cross-Linking Reagents; Ethidium; Ethyl Methanesulfonate; Female; Humans; | 2009 |
A simple non-radioactive method for diagnosis of Huntington's disease.
Topics: DNA; Electrophoresis, Polyacrylamide Gel; Ethidium; Humans; Huntington Disease; Polymerase Chain Rea | 1993 |