ethidium has been researched along with Chagas Disease in 5 studies
Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schijman, AG | 1 |
| Altcheh, J | 1 |
| Burgos, JM | 1 |
| Biancardi, M | 1 |
| Bisio, M | 1 |
| Levin, MJ | 1 |
| Freilij, H | 1 |
| Schwick, HG | 1 |
| Hungerer, KD | 1 |
| Zwisler, O | 1 |
| Jennings, FW | 1 |
| Gray, GD | 1 |
| Jadin, JM | 1 |
| Trouet, A | 1 |
| Van Hoof, F | 1 |
| Bioul-Marchand, M | 1 |
| Maldague, P | 1 |
| Jadin-Nyssens, M | 1 |
| Avila, JL | 1 |
| Bretaña, A | 1 |
| Avila, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2 Randomized, Multicenter, Double-blinded Safety and Efficacy Study to Evaluate Oral Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chronic Indeterminate Chagas Disease[NCT03587766] | Phase 2 | 45 participants (Actual) | Interventional | 2017-11-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ethidium and Chagas Disease
| Article | Year |
|---|---|
Aetiological treatment of congenital Chagas' disease diagnosed and monitored by the polymerase chain reaction.
Topics: Adolescent; Animals; Antiparasitic Agents; Argentina; Chagas Disease; Child; Child, Preschool; DNA P | 2003 |
4 other studies available for ethidium and Chagas Disease
| Article | Year |
|---|---|
Vaccination trials against S. mansoni and T. cruzi in experimental animals.
Topics: Animals; Chagas Disease; Dactinomycin; Disease Models, Animal; Ethidium; Granulocytes; Humans; Male; | 1980 |
The possible use of Trypanosoma musculi infection in mice as a screening test for potential Trypanosoma cruzi-active drugs.
Topics: Animals; Chagas Disease; Diminazene; Drug Evaluation, Preclinical; Ethidium; Female; Kidney; Mice; N | 1982 |
[Comparative study of lysosomotropic chemotherapy of Chagas' disease and nagana].
Topics: Animals; Chagas Disease; Ethidium; Lysosomes; Mice; Mice, Inbred C57BL; Trypanocidal Agents; Trypano | 1977 |
Chemotherapy with ethidium bromide-DNA complex in established Chagas' disease.
Topics: Animals; Chagas Disease; DNA; Drug Combinations; Ethidium; Mice; Mitosis; Trypanosoma cruzi | 1979 |