Page last updated: 2024-10-28

ethidium and Cell Transformation, Neoplastic

ethidium has been researched along with Cell Transformation, Neoplastic in 22 studies

Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"Radon was further found to depress mitochondrial membrane potential (MMP) of HBE cells with knockdown mtDNA."1.38Radon-induced reduced apoptosis in human bronchial epithelial cells with knockdown of mitochondria DNA. ( Cheng, YZ; Cheng, ZH; Hei, TK; Li, BY; Sun, J; Tong, J; Wan, JM; Wang, AQ; Wei, H; Xue, L, 2012)
"To investigate the role of mtDNA in prostate cancer progression, we used LNCaP and PC-3 prostate carcinoma cells as experimental model."1.35Mitochondrial DNA depletion reduces PARP-1 levels and promotes progression of the neoplastic phenotype in prostate carcinoma. ( Arbini, AA; Greco, M; Marra, E; Moro, L, 2008)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199017 (77.27)18.7374
1990's2 (9.09)18.2507
2000's2 (9.09)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moro, L1
Arbini, AA1
Marra, E1
Greco, M1
Li, BY1
Sun, J1
Wei, H1
Cheng, YZ1
Xue, L1
Cheng, ZH1
Wan, JM1
Wang, AQ1
Hei, TK1
Tong, J1
Barlogie, B1
Drewinko, B1
Schumann, J1
Göhde, W1
Dosik, G1
Latreille, J1
Johnston, DA1
Freireich, EJ1
Glazer, VM1
Luchnik, AN1
Nakayama, F1
Kurosu, K1
Yumoto, N1
Mikata, A1
Ghiselli, G1
Iozzo, RV1
Soslau, G3
Nass, MM4
Wilkie, D1
Egilsson, V1
Evans, IH1
Svoboda, J1
Hlozánek, I1
Korb, J1
Mach, O1
Roa, RC1
Bose, SK1
Ide, T1
Baserga, R1
Hawkes, SP1
Bartholomew, JC1
Mishra, NK1
Pant, KJ1
Thomas, FO1
Price, PJ1
Zinkewich-Péotti, K1
Parent, M1
Morais, R1
Balda, BR1
Birkmayer, GD1
Cramer, R1
Yoshikura, H1
Meyer, G1
Bader, AV1
Klietmann, W1
Sato, N1
Fuhrer, JP1
Warren, L1
Altaner, C1
Matoska, J1

Other Studies

22 other studies available for ethidium and Cell Transformation, Neoplastic

ArticleYear
Mitochondrial DNA depletion reduces PARP-1 levels and promotes progression of the neoplastic phenotype in prostate carcinoma.
    Cellular oncology : the official journal of the International Society for Cellular Oncology, 2008, Volume: 30, Issue:4

    Topics: Androgens; Apoptosis; Carcinogens; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Cell Tran

2008
Radon-induced reduced apoptosis in human bronchial epithelial cells with knockdown of mitochondria DNA.
    Journal of toxicology and environmental health. Part A, 2012, Volume: 75, Issue:18

    Topics: Apoptosis; Bronchi; Carcinogens, Environmental; Cell Cycle; Cell Line; Cell Transformation, Neoplast

2012
Cellular DNA content as a marker of neoplasia in man.
    The American journal of medicine, 1980, Volume: 69, Issue:2

    Topics: Adult; Age Factors; Aged; Aneuploidy; Cell Count; Cell Transformation, Neoplastic; Cytogenetics; DNA

1980
[Change in the topologic bond number of closed DNA loops during differentiation of mouse erythroleukemia cells].
    Doklady Akademii nauk SSSR, 1980, Volume: 250, Issue:5

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Clone

1980
Immunoglobulin gene analysis of cutaneous pseudolymphoma by polymerase chain reaction.
    The Journal of dermatology, 1995, Volume: 22, Issue:6

    Topics: Adult; B-Lymphocytes; Cell Transformation, Neoplastic; Child; DNA, Neoplasm; Electrophoresis, Agar G

1995
Overexpression of bamacan/SMC3 causes transformation.
    The Journal of biological chemistry, 2000, Jul-07, Volume: 275, Issue:27

    Topics: Animals; Cell Cycle Proteins; Cell Transformation, Neoplastic; Chondroitin Sulfate Proteoglycans; Ch

2000
Stimulation of 2-deoxy-d-glucose transport in control and virus-transformed cells by ethidium bromide.
    Journal of cellular physiology, 1975, Volume: 86, Issue:2 Pt 1

    Topics: Avian Sarcoma Viruses; Biological Transport, Active; Cell Count; Cell Line; Cell Transformation, Neo

1975
Letter: Mitochondria in oncogenesis.
    Lancet (London, England), 1975, Mar-22, Volume: 1, Issue:7908

    Topics: Acriflavine; Animals; Bromides; Carcinogens; Cell Membrane; Cell Transformation, Neoplastic; Daunoru

1975
Virus-like particles associated with the mitochondria of ethidium bromide treated transformed cells.
    The Journal of general virology, 1978, Volume: 40, Issue:1

    Topics: Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Ethid

1978
Failure to obtain transfection with XC mitochondrial DNA.
    European journal of cancer, 1975, Volume: 11, Issue:4

    Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Chickens;

1975
Requirement for cellular protein synthesis in reversal of ethidium-bormide-induced inhibition of cell transformation by murine sarcoma virus.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:11

    Topics: Cell Line; Cell Transformation, Neoplastic; Chloramphenicol; Cycloheximide; Dactinomycin; Deoxyadeno

1975
Circular dichroism and ethidium bromide binding capacity of chromatin from cells temperature sensitive for the transformed phenotype.
    Biochemistry, 1976, Feb-10, Volume: 15, Issue:3

    Topics: Binding Sites; Cell Division; Cell Line; Cell Transformation, Neoplastic; Circular Dichroism; DNA; D

1976
Quantitative determination of transformed cells in a mixed population by stimultaneous fluorescence analysis of cell surface and DNA an individual cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:4

    Topics: Cell Line; Cell Transformation, Neoplastic; DNA; DNA Replication; DNA, Neoplasm; Ethidium; Fluoresca

1977
Chemical-viral co-carcinogenesis: requirement for leukemia virus expression in accelerated transformation.
    International journal of cancer, 1976, Dec-15, Volume: 18, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cell Transformation, Neoplastic; Clone Cells; Cocarcinogenesis; DNA

1976
Mitochondrial DNA modulation of the anchorage-independent phenotype of transformed avian cells.
    Cancer research, 1990, Oct-15, Volume: 50, Issue:20

    Topics: Animals; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; DNA, Mitochondrial;

1990
Drug effects in melanoma: tumor-specific interactions of proflavine and ethidiumbromide.
    The Yale journal of biology and medicine, 1973, Volume: 46, Issue:5

    Topics: Acridines; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Centrifugation, Density

1973
Differential effects of ethidium bromide on mitochondrial and nuclear DNA synthesis in vivo in cultured mammalian cells.
    Experimental cell research, 1972, Volume: 72, Issue:1

    Topics: Animals; Bromides; Carbon Isotopes; Cell Count; Cell Fractionation; Cell Line; Cell Nucleus; Cell Tr

1972
A specific inhibitor of polyoma virus in infected rat and hamster cells and in transformed clones of hamster cells.
    The Journal of general virology, 1972, Volume: 16, Issue:3

    Topics: Animals; Antiviral Agents; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Centrifugati

1972
Role of mitochondria in the production of RNA-containing tumor viruses.
    Journal of virology, 1973, Volume: 11, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chick E

1973
Establishment and characterization of ethidium bromide resistance in simian virus 40-transformed hamster cells. Effects on mitochondria in vivo.
    The Journal of cell biology, 1973, Volume: 58, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradi

1973
The effect of ethidium bromide on the membrane glycopeptides in control and virus-transformed cells.
    The Journal of biological chemistry, 1974, May-25, Volume: 249, Issue:10

    Topics: Animals; Avian Sarcoma Viruses; Carbon Radioisotopes; Cell Line; Cell Nucleus; Cell Transformation,

1974
Avian sarcoma virus transformed hamster cells made resistant to ethidium bromide.
    Journal of cell science, 1974, Volume: 16, Issue:3

    Topics: Alpharetrovirus; Animals; Bromides; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Cells,

1974