ethidium has been researched along with Breast Neoplasms in 19 studies
Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As per the reports, the choice of drug in the treatment of breast cancer is paclitaxel, but the major limitation is its toxicity." | 7.77 | Unravelling the antimetastatic potential of pentoxifylline, a methylxanthine derivative in human MDA-MB-231 breast cancer cells. ( Goel, PN; Gude, RP, 2011) |
| "In order to investigate the role of mitochondrial DNA (mtDNA) in human breast cancer cell proliferation and apoptosis, a mtDNA-deficient cell line, T47D rho(0), was generated following a long-term exposure to ethidium bromide (EtBr)." | 7.74 | Depletion of mitochondrial DNA by ethidium bromide treatment inhibits the proliferation and tumorigenesis of T47D human breast cancer cells. ( Hao, X; Niu, R; Shi, Y; Wei, X; Yang, Y; Yu, M; Zhang, N; Zhou, Y, 2007) |
| " We studied the binding of carboplatin to calf thymus DNA in the presence of thiourea, glutathione, and human breast cancer MCF-7 cell cytoplasmic extracts by measurement of DNA-dependent ethidium bromide fluorescence and atomic absorption spectroscopy." | 7.70 | Increased DNA-binding activity of cis-1,1-cyclobutanedicarboxylatodiammineplatinum(II) (carboplatin) in the presence of nucleophiles and human breast cancer MCF-7 cell cytoplasmic extracts: activation theory revisited. ( Holler, E; Malathi, R; Natarajan, G, 1999) |
| " As per the reports, the choice of drug in the treatment of breast cancer is paclitaxel, but the major limitation is its toxicity." | 3.77 | Unravelling the antimetastatic potential of pentoxifylline, a methylxanthine derivative in human MDA-MB-231 breast cancer cells. ( Goel, PN; Gude, RP, 2011) |
| "In order to investigate the role of mitochondrial DNA (mtDNA) in human breast cancer cell proliferation and apoptosis, a mtDNA-deficient cell line, T47D rho(0), was generated following a long-term exposure to ethidium bromide (EtBr)." | 3.74 | Depletion of mitochondrial DNA by ethidium bromide treatment inhibits the proliferation and tumorigenesis of T47D human breast cancer cells. ( Hao, X; Niu, R; Shi, Y; Wei, X; Yang, Y; Yu, M; Zhang, N; Zhou, Y, 2007) |
| " Evaluation of the cytotoxicity of these compounds employing a MTT assay and inhibition of [(3)H]thymidine incorporation into DNA in both MDA-MB-231 and MCF-7 human breast cancer cells demonstrated that these compounds were more active than melphalan." | 3.74 | Amidine analogues of melphalan: synthesis, cytotoxic activity, and DNA binding properties. ( Anchim, T; Bielawska, A; Bielawski, K, 2007) |
| "Although the net benefits of tamoxifen in adjuvant breast cancer therapy have been proven, the recurrence of the cancer in an aggressive and hormone independent form has been highly problematic." | 3.74 | Induction of acquired resistance to antiestrogen by reversible mitochondrial DNA depletion in breast cancer cell line. ( Carcel-Trullols, J; Evans, TT; Higuchi, M; Mizumachi, T; Naito, A; Xie, CH, 2008) |
| "A number of novel cyclic amidine analogs of chlorambucil were synthesized and examined for cytotoxicity in breast cancer cell cultures and for inhibition of topoisomerases I and II." | 3.72 | Synthesis and biological evaluation of new cyclic amidine analogs of chlorambucil. ( Bielawska, A; Bielawski, K; Muszyńska, A, 2004) |
| " We studied the binding of carboplatin to calf thymus DNA in the presence of thiourea, glutathione, and human breast cancer MCF-7 cell cytoplasmic extracts by measurement of DNA-dependent ethidium bromide fluorescence and atomic absorption spectroscopy." | 3.70 | Increased DNA-binding activity of cis-1,1-cyclobutanedicarboxylatodiammineplatinum(II) (carboplatin) in the presence of nucleophiles and human breast cancer MCF-7 cell cytoplasmic extracts: activation theory revisited. ( Holler, E; Malathi, R; Natarajan, G, 1999) |
| "Breast and cervical cancer cells that stably expressed apoptotic sensor proteins were used to determine apoptosis in real-time by fluorescence resonance energy transfer (FRET)-based imaging microscopy." | 1.48 | Fluidic shear stress increases the anti-cancer effects of ROS-generating drugs in circulating tumor cells. ( Fung, TS; Lim, S; Luo, KQ; Regmi, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Tülüce, Y | 1 |
| Hussein, AI | 1 |
| Koyuncu, İ | 1 |
| Kiliç, A | 1 |
| Durgun, M | 1 |
| Singh, B | 1 |
| Kisku, T | 1 |
| Das, S | 1 |
| Mukherjee, S | 1 |
| Kundu, A | 1 |
| Rath, J | 1 |
| Das, RS | 1 |
| Shams Abyaneh, FS | 1 |
| Eslami Moghadam, M | 1 |
| Divsalar, A | 1 |
| Ajloo, D | 1 |
| Hosaini Sadr, M | 1 |
| Regmi, S | 1 |
| Fung, TS | 1 |
| Lim, S | 1 |
| Luo, KQ | 1 |
| Anjomshoa, M | 1 |
| Hadadzadeh, H | 1 |
| Fatemi, SJ | 1 |
| Torkzadeh-Mahani, M | 1 |
| Wang, X | 1 |
| Yan, M | 1 |
| Wang, Q | 1 |
| Wang, H | 1 |
| Wang, Z | 1 |
| Zhao, J | 1 |
| Li, J | 1 |
| Zhang, Z | 1 |
| Villa, AM | 1 |
| Doglia, SM | 1 |
| Goel, PN | 1 |
| Gude, RP | 1 |
| Lakhotia, S | 1 |
| Somasundaram, K | 1 |
| Bielawska, A | 2 |
| Bielawski, K | 2 |
| Muszyńska, A | 1 |
| Felty, Q | 1 |
| Singh, KP | 1 |
| Roy, D | 1 |
| Yu, M | 1 |
| Shi, Y | 1 |
| Wei, X | 1 |
| Yang, Y | 1 |
| Zhou, Y | 1 |
| Hao, X | 1 |
| Zhang, N | 1 |
| Niu, R | 1 |
| Anchim, T | 1 |
| Naito, A | 1 |
| Carcel-Trullols, J | 1 |
| Xie, CH | 1 |
| Evans, TT | 1 |
| Mizumachi, T | 1 |
| Higuchi, M | 1 |
| Sestini, R | 1 |
| Orlando, C | 1 |
| Zentilin, L | 1 |
| Gelmini, S | 1 |
| Pinzani, P | 1 |
| Bianchi, S | 1 |
| Selli, C | 1 |
| Giacca, M | 1 |
| Pazzagli, M | 1 |
| Natarajan, G | 1 |
| Malathi, R | 1 |
| Holler, E | 1 |
| Mira, E | 1 |
| Lacalle, RA | 1 |
| Gómez-Moutón, C | 1 |
| Leonardo, E | 1 |
| Mañes, S | 1 |
| Cohen, BB | 1 |
| Wallace, MR | 1 |
| Crichton, DN | 1 |
| Sarkar, FH | 1 |
| Li, YW | 1 |
| Ball, DE | 1 |
| Crissman, JD | 1 |
19 other studies available for ethidium and Breast Neoplasms
| Article | Year |
|---|---|
The effect of a bis-structured Schiff base on apoptosis, cytotoxicity, and DNA damage of breast cancer cells.
Topics: Acridine Orange; Antineoplastic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Proliferatio | 2022 |
Refashioning of the drug-properties of fluoroquinolone through the synthesis of a levofloxacin-imidazole cobalt (II) complex and its interaction studies on with DNA and BSA biopolymers, antimicrobial and cytotoxic studies on breast cancer cell lines.
Topics: Anti-Infective Agents; Antioxidants; Biopolymers; Breast Neoplasms; Cobalt; Coordination Complexes; | 2023 |
Improving of Anticancer Activity and Solubility of Cisplatin by Methylglycine and Methyl Amine Ligands Against Human Breast Adenocarcinoma Cell Line.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Circular Dichroism; Cisplatin; DNA; Ethidiu | 2018 |
Fluidic shear stress increases the anti-cancer effects of ROS-generating drugs in circulating tumor cells.
Topics: Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Doxorubicin; | 2018 |
A mononuclear Ni(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: DNA- and BSA-binding and anticancer activity against human breast carcinoma cells.
Topics: Animals; Antineoplastic Agents; Binding, Competitive; Breast Neoplasms; Cattle; Coordination Complex | 2015 |
In Vitro DNA-Binding, Anti-Oxidant and Anticancer Activity of Indole-2-Carboxylic Acid Dinuclear Copper(II) Complexes.
Topics: Animals; Antioxidants; Breast Neoplasms; Carboxylic Acids; Cattle; Cell Line, Tumor; Copper; DNA; Et | 2017 |
Ethidium bromide as a vital probe of mitochondrial DNA in carcinoma cells.
Topics: Breast; Breast Neoplasms; Calcium Channel Blockers; Cell Line, Tumor; DNA, Mitochondrial; Drug Resis | 2009 |
Unravelling the antimetastatic potential of pentoxifylline, a methylxanthine derivative in human MDA-MB-231 breast cancer cells.
Topics: Acridine Orange; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Move | 2011 |
Conformation-sensitive gel electrophoresis for detecting BRCA1 mutations.
Topics: Breast Neoplasms; Ethidium; Exons; Female; Genes, BRCA1; Genetic Techniques; Humans; Models, Genetic | 2003 |
Synthesis and biological evaluation of new cyclic amidine analogs of chlorambucil.
Topics: Antineoplastic Agents, Alkylating; Binding, Competitive; Breast Neoplasms; Cell Line, Tumor; Cell Su | 2004 |
Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling.
Topics: Base Sequence; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Chloramphenicol; DNA P | 2005 |
Depletion of mitochondrial DNA by ethidium bromide treatment inhibits the proliferation and tumorigenesis of T47D human breast cancer cells.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA, Mitochondrial; Ethi | 2007 |
Amidine analogues of melphalan: synthesis, cytotoxic activity, and DNA binding properties.
Topics: Amidines; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Surviv | 2007 |
Induction of acquired resistance to antiestrogen by reversible mitochondrial DNA depletion in breast cancer cell line.
Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Blotting, Southern; Blotting, Western; Breast Neopl | 2008 |
Measuring c-erbB-2 oncogene amplification in fresh and paraffin-embedded tumors by competitive polymerase chain reaction.
Topics: Base Sequence; Breast Neoplasms; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; | 1994 |
Increased DNA-binding activity of cis-1,1-cyclobutanedicarboxylatodiammineplatinum(II) (carboplatin) in the presence of nucleophiles and human breast cancer MCF-7 cell cytoplasmic extracts: activation theory revisited.
Topics: Antineoplastic Agents; Breast Neoplasms; Carboplatin; Cell Extracts; DNA; Ethidium; Fluorescence; Hu | 1999 |
Quantitative determination of tumor cell intravasation in a real-time polymerase chain reaction-based assay.
Topics: Adenocarcinoma; Allantois; Alu Elements; Animals; Benzothiazoles; Breast Neoplasms; Chick Embryo; Ch | 2002 |
A comparison of procedures for analysing microsatellite (CA)-repeat polymorphisms.
Topics: Breast Neoplasms; DNA; DNA, Neoplasm; Ethidium; Genetic Markers; Humans; Leukocytes, Mononuclear; Ol | 1992 |
Comparative method for detection of RNA-PCR-amplified signals.
Topics: Base Sequence; Blotting, Southern; Breast Neoplasms; Electrophoresis, Polyacrylamide Gel; Ethidium; | 1992 |