Page last updated: 2024-10-28

ethidium and Ataxia Telangiectasia

ethidium has been researched along with Ataxia Telangiectasia in 2 studies

Ethidium: A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
ethidium : The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research Excerpts

ExcerptRelevanceReference
" Linear dose-response curves were obtained for both dose ranges."1.27Quantitative measurement of DNA strand breaks and repair in gamma-irradiated human leukocytes from normal and ataxia telangiectasia donors. ( Duranton, I; Magdelenat, H; Moustacchi, E; Rigaud, O; Thierry, D, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lavin, MF1
Davidson, M1
Thierry, D1
Rigaud, O1
Duranton, I1
Moustacchi, E1
Magdelenat, H1

Other Studies

2 other studies available for ethidium and Ataxia Telangiectasia

ArticleYear
Repair of strand breaks in superhelical DNA of ataxia telangiectasia lymphoblastoid cells.
    Journal of cell science, 1981, Volume: 48

    Topics: Ataxia Telangiectasia; Cell Line; Centrifugation, Density Gradient; DNA Repair; DNA, Superhelical; E

1981
Quantitative measurement of DNA strand breaks and repair in gamma-irradiated human leukocytes from normal and ataxia telangiectasia donors.
    Radiation research, 1985, Volume: 102, Issue:3

    Topics: Ataxia Telangiectasia; Cell Count; Cysteamine; DNA; DNA Repair; Dose-Response Relationship, Radiatio

1985