ether has been researched along with Long QT Syndrome in 2 studies
Ether: A mobile, very volatile, highly flammable liquid used as an inhalation anesthetic and as a solvent for waxes, fats, oils, perfumes, alkaloids, and gums. It is mildly irritating to skin and mucous membranes.
ether : An organooxygen compound with formula ROR, where R is not hydrogen.
diethyl ether : An ether in which the oxygen atom is linked to two ethyl groups.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human Ether-à-go-go (hERG) channels contribute to cardiac repolarization, and inherited variants or drug block are associated with long QT syndrome type 2 (LQTS2) and arrhythmia." | 4.02 | Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243. ( Claydon, TW; Johal, R; Kemp, JM; Mirams, GR; Pang, Z; Sergeev, V; Tibbits, GF; Venkateshappa, R; Whittaker, DG, 2021) |
| " Small molecule drugs containing a nitrogen that can be protonated to afford a formal +1 charge can interact with hERG to prevent the repolarization of outward rectifier currents." | 1.72 | New Insights into Ion Channels: Predicting hERG-Drug Interactions. ( Wempe, MF, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wempe, MF | 1 |
| Kemp, JM | 1 |
| Whittaker, DG | 1 |
| Venkateshappa, R | 1 |
| Pang, Z | 1 |
| Johal, R | 1 |
| Sergeev, V | 1 |
| Tibbits, GF | 1 |
| Mirams, GR | 1 |
| Claydon, TW | 1 |
2 other studies available for ether and Long QT Syndrome
| Article | Year |
|---|---|
New Insights into Ion Channels: Predicting hERG-Drug Interactions.
Topics: Drug Interactions; Ether; Ether-A-Go-Go Potassium Channels; Humans; Ion Channels; Long QT Syndrome; | 2022 |
Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243.
Topics: Arrhythmias, Cardiac; ERG1 Potassium Channel; Ether; Ether-A-Go-Go Potassium Channels; Humans; Long | 2021 |