ethamolin and Mouth-Neoplasms

The objective of this study was to report and discuss the results from treatment of benign oral vascular lesions with ethanolamine oleate.. Twenty-seven patients with 30 examples of oral vascular malformation, hemangioma, or varix were treated with intralesional injections of 1.25% or 2.5% ethanolamine oleate at an interval of 15 days between each application. The lesions were divided into 2 categories: (1) lesions of 20 mm or less and (2) those greater than 20 mm. Subsequently, the Mann-Whitney test was used a means of statistical analysis.. Although the number of injections varied from patient to patient, all lesions responded to the treatment, showing total clinical regression. Lesions of 20 mm or less needed a lesser number of applications than those greater than 20 mm (P < .05).. Ethanolamine oleate is a 100% effective sclerosant agent for treatment of benign oral vascular lesions. In this study, no difference was found between the 2 concentrations applied.

Topics: Adolescent; Adult; Aged; Arteriovenous Malformations; Child; Female; Hemangioma; Humans; Injections, Intralesional; Male; Middle Aged; Mouth Diseases; Mouth Neoplasms; Neoplasms, Vascular Tissue; Oleic Acids; Sclerosing Solutions; Sclerotherapy; Statistics, Nonparametric; Varicose Veins; Vascular Diseases

Although sclerotherapy is a common treatment for benign oral vascular lesions, there is no well-standardized protocol for this purpose. The aim of the present study was to describe the clinical characteristics of patients treated by sclerotherapy with ethanolamine oleate (EO), in order to contribute to a better understanding of this technique.. Medical records and images of 90 patients treated by the same sclerotherapy protocol were retrieved and analysed. Thus, 43 cases with complete information were selected and described.. The most affected age group was 41-70 years, with a female predominance and 86% of patients being Caucasian. Lips were the most affect site (70%) followed by the tongue (16%). Regarding clinical appearance, approximately 90% of lesions were classified as nodules, and 90% of patients reported no pain. Approximately 40% of lesions were 0.5-1.0 cm in size. In 58% of the patients, only one application of ethanolamine oleate was necessary. The application doses varied according to the lesion size and number of applications. Complete clinical regression occurred in 91% of cases, whereas 9% showed partial regression.. Sclerotherapy with EO is an acceptable, effective and affordable treatment for benign oral vascular lesions.

Topics: Adolescent; Adult; Aged; Blood Vessels; Child; Congenital Abnormalities; Female; Hemangioma; Humans; Male; Middle Aged; Mouth; Mouth Neoplasms; Oleic Acids; Retrospective Studies; Sclerosing Solutions; Sclerotherapy; Young Adult

Hemangiomas are benign vascular anomalies characterized by benign proliferation of blood vessels. There are no well-defined criteria for the diagnosis and treatment of oral capillary hemangioma (OCH). The objective of this study is to report a safe, effective, and low-cost protocol for diagnosis and treatment of OCH.. Eight patients were diagnosed with OCH, through two physical examination maneuvers-the diascopy and head lowering maneuver with abdominal compression (HLMAC). The treatment performed was sclerotherapy with ethanolamine oleate, weekly, until the disappearance of the lesion. No local anesthetics were administered prior to the sclerosing agent injection.. All cases showed a complete remission of the lesions after sclerotherapy. There were no visible scars or compromise esthetics or normal function, and there was no evidence of recurrence. Only one patient had superficial ulceration, which remained asymptomatic and healed without specific treatment.. This protocol was effective in the diagnosis of OCH through two physical examination maneuvers with low-cost and easy implementation, the diascopy and the HLMAC. The low concentration associated with a reduced amount of the sclerosing agent was responsible for the excellent results in the cases treated.

Topics: Adult; Clinical Protocols; Head Movements; Hemangioma, Capillary; Humans; Mouth Neoplasms; Oleic Acids; Physical Examination; Pressure; Remission Induction; Sclerosing Solutions; Sclerotherapy