Page last updated: 2024-08-21

ethambutol and Disease Models, Animal

ethambutol has been researched along with Disease Models, Animal in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19906 (16.67)18.7374
1990's8 (22.22)18.2507
2000's8 (22.22)29.6817
2010's12 (33.33)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Bhakta, S; Boshoff, HI; Evangelopoulos, D; Gibbons, S; Gunaratnam, M; Lenaerts, A; Malkinson, JP; Moreira, JB; Neidle, S; O'Donnell, G; Poeschl, R; Zimhony, O1
Angulo-Barturen, I; Beltrán, M; Cáceres, N; Cardona, PJ; García, JI; García-Bustos, JF; Rullas, J1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Cao, LH; Kang, L; Liu, HJ; Miao, JX; Miao, MS; Miao, YY; Song, YG; Xiang, LL1
Bakker-Woudenberg, IAJM; Davies, GR; de Knegt, GJ; de Steenwinkel, JEM; Dickinson, L; Evangelopoulos, D; McHugh, TD; Pertinez, H1
Bax, HI; de Knegt, GJ; de Steenwinkel, JEM; Mourik, BC; Mouton, JW; Verbon, A1
Bhatta, RS; Chauhan, S; Chopra, S; Dasgupta, A; Gupta, P; Gupta, UD; Karaulia, P; Puttrevu, SK; Singh, AK; Singh, VK; Tadigoppula, N; Yadav, P1
Luukinen, H; Myllymäki, H; Niskanen, M; Parikka, M; Rämet, M1
Bax, HI; de Knegt, GJ; de Steenwinkel, JEM; Mourik, BC; Simonsson, USH; Svensson, RJ; Verbon, A1
Coates, AR; Davies, GR; Gillespie, SH; Hu, Y; Liu, Y; Pertinez, H1
Betoudji, F; Lanoix, JP; Nuermberger, E1
Adamson, J; Almeida, DV; Ammerman, NC; Bester, LA; Dorasamy, A; Grosset, JH; Mgaga, Z; Moodley, C; Moodley, S; Ngcobo, B; Singh, SD; Swanson, RV1
Alameda, L; Chen, C; Ferrer, S; Ortega, F; Simonsson, US1
Almeida, D; Grosset, JH; Karakousis, PC; Mdluli, KE; Nuermberger, EL; Peloquin, CA; Rosenthal, IM; Tasneen, R; Zhang, M1
Iwata, N; Kimotsuki, T; Kinoshita, J; Maejima, T; Yasuda, M1
Bermudez, LE; Inderlied, CB; Kolonoski, P; Petrofsky, M; Wu, M; Young, LS1
Boelaert, RJ; Grosset, J; Lounis, N; Maslo, C; Truffot-Pernot, C1
Cynamon, MH; Sklaney, M; Yeo, AE1
Chen, P; Einck, L; Gearhart, J; Hanrahan, C; Nacy, CA; Nikonenko, B; Protopopova, M; Samala, R1
Almeida, D; Bishai, WR; Grosset, JH; Nuermberger, E; Peloquin, CA; Rosenthal, I; Tyagi, S; Williams, KN1
Kuze, F1
Durr, FE; Thomas, JP1
Graybill, JR; Moreno, F; Valero, G1
Brummer, E; Deresinski, SC; Hamilton, JR; Kemper, CA; Sison, JP; Stevens, DA; Yao, Y1
Bermudez, LE; Inderlied, CB; Nash, KA; Petrofsky, M; Young, LS1
Chase, SE; Cynamon, MH; Lenaerts, AM1
Kaur, D; Khuller, GK1
Cohen, Y; Grosset, J; Perronne, C; Pocidalo, JJ; Truffot-Pernot, C; Vildé, JL1
Cynamon, MH; DeStefano, MS; Klemens, SP1
Skakun, NP; Tabachuk, OE1
Neumeyer, C; Spekreijse, H; Wietsma, JJ1
Byrne, C; Clancy, LJ; Costello, E; Kelly, P; O'Reilly, L1
Rosenfeld, M1
Horai, Z; Matsumura, K; Shimizu, K; Ueda, Y; Yoneda, H1
Drabkina, RO; Ginzburg, TS1
Kradolfer, F; Schnell, R1

Trials

1 trial(s) available for ethambutol and Disease Models, Animal

ArticleYear
Treatment of Myocardium avium complex infection: does the beige mouse model predict therapeutic outcome in humans?
    The Journal of infectious diseases, 1996, Volume: 173, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Animals; Antitubercular Agents; Clofazimine; Colony Count, Microbial; Disease Models, Animal; Ethambutol; Humans; Liver; Mice; Mycobacterium avium-intracellulare Infection; Rifampin; Species Specificity; Spleen

1996

Other Studies

35 other study(ies) available for ethambutol and Disease Models, Animal

ArticleYear
Bioactive pyridine-N-oxide disulfides from Allium stipitatum.
    Journal of natural products, 2009, Mar-27, Volume: 72, Issue:3

    Topics: 2,2'-Dipyridyl; Alkaloids; Allium; Animals; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Disulfides; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Heat-Shock Proteins; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Molecular Structure; Oxyquinoline; Pyridines; Thioredoxins; Vitamin K 3

2009
Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Acetamides; Animals; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Discovery; Ethambutol; Fluoroquinolones; Immunocompetence; Inhalation Exposure; Isoniazid; Linezolid; Mice; Mice, Inbred C57BL; Moxifloxacin; Oxazolidinones; Pyrazinamide; Quinolines; Reproducibility of Results; Rifampin; Tuberculosis, Pulmonary

2010
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Total glucosides of herbaceous peony (Paeonia lactiflora Pall.) flower attenuate adenine- and ethambutol-induced hyperuricaemia in rats.
    Journal of ethnopharmacology, 2020, Oct-28, Volume: 261

    Topics: Adenine; Animals; Biomarkers; Disease Models, Animal; Down-Regulation; Ethambutol; Flowers; Glucosides; Hyperuricemia; Kidney; Male; Paeonia; Plant Extracts; Rats, Wistar; Uric Acid; Uricosuric Agents

2020
Assessment of treatment response by colony forming units, time to culture positivity and the molecular bacterial load assay compared in a mouse tuberculosis model.
    Tuberculosis (Edinburgh, Scotland), 2017, Volume: 105

    Topics: Animals; Antitubercular Agents; Bacterial Load; Colony Count, Microbial; Disease Models, Animal; DNA, Bacterial; Ethambutol; Female; Isoniazid; Lung; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nonlinear Dynamics; Predictive Value of Tests; Pyrazinamide; Ribotyping; Rifampin; RNA, Ribosomal, 16S; Streptomycin; Time Factors; Tuberculosis, Pulmonary

2017
Assessment of Bactericidal Drug Activity and Treatment Outcome in a Mouse Tuberculosis Model Using a Clinical Beijing Strain.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:10

    Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Treatment Outcome; Tuberculosis, Pulmonary

2017
Biological evaluation of novel curcumin-pyrazole-mannich derivative active against drug-resistant Mycobacterium tuberculosis.
    Future microbiology, 2017, Volume: 12

    Topics: Animals; Antitubercular Agents; Bacterial Load; Curcumin; Disease Models, Animal; Drug Combinations; Drug Synergism; Ethambutol; Female; Humans; Mannich Bases; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazoles; Time Factors; Tuberculosis, Multidrug-Resistant

2017
Identification of protective postexposure mycobacterial vaccine antigens using an immunosuppression-based reactivation model in the zebrafish.
    Disease models & mechanisms, 2018, 03-13, Volume: 11, Issue:3

    Topics: Animals; Antigens, Bacterial; Bacterial Load; Biomarkers; Dexamethasone; Disease Models, Animal; Ethambutol; Granuloma; Hypoxia; Immunosuppression Therapy; Lymphocyte Depletion; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; T-Lymphocytes; Tuberculosis Vaccines; Zebrafish

2018
Improving treatment outcome assessment in a mouse tuberculosis model.
    Scientific reports, 2018, 04-09, Volume: 8, Issue:1

    Topics: Administration, Oral; Animals; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Genotype; Humans; Mice; Mice, Inbred BALB C; Models, Theoretical; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis

2018
Moxifloxacin Replacement in Contemporary Tuberculosis Drug Regimens Is Ineffective against Persistent Mycobacterium tuberculosis in the Cornell Mouse Model.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:7

    Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Moxifloxacin; Mycobacterium tuberculosis; Recurrence; Tuberculosis, Pulmonary

2018
Sterilizing Activity of Pyrazinamide in Combination with First-Line Drugs in a C3HeB/FeJ Mouse Model of Tuberculosis.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:2

    Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice, Inbred BALB C; Mice, Inbred C3H; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary

2016
Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5

    Topics: Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Withholding Treatment

2016
Population pharmacokinetics, optimised design and sample size determination for rifampicin, isoniazid, ethambutol and pyrazinamide in the mouse.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Oct-10, Volume: 93

    Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Ethambutol; Isoniazid; Mice, Inbred C57BL; Models, Biological; Pyrazinamide; Rifampin; Sample Size

2016
Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8

    Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Isoniazid; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Random Allocation; Rifampin; Treatment Outcome; Tuberculosis, Pulmonary

2012
Retinal function and morphology in monkeys with ethambutol-induced optic neuropathy.
    Investigative ophthalmology & visual science, 2012, Oct-09, Volume: 53, Issue:11

    Topics: Administration, Oral; Animals; Antitubercular Agents; Dark Adaptation; Disease Models, Animal; Electroretinography; Ethambutol; Macaca fascicularis; Microglia; Necrosis; Nerve Fibers; Optic Nerve Diseases; Photic Stimulation; Retina; Retinal Ganglion Cells

2012
Mefloquine, moxifloxacin, and ethambutol are a triple-drug alternative to macrolide-containing regimens for treatment of Mycobacterium avium disease.
    The Journal of infectious diseases, 2003, Jun-15, Volume: 187, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Aza Compounds; Clarithromycin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mefloquine; Mice; Moxifloxacin; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Quinolines

2003
Impact of iron loading on the activity of isoniazid or ethambutol in the treatment of murine tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2003, Volume: 7, Issue:6

    Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Interactions; Ethambutol; Female; Iron; Isoniazid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Survival Rate; Time Factors; Treatment Outcome; Tuberculosis

2003
The activity of grepafloxacin in two murine models of Mycobacterium avium infection.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2004, Volume: 10, Issue:3

    Topics: Administration, Intranasal; Animals; Clarithromycin; Disease Models, Animal; Ethambutol; Female; Fluoroquinolones; Injections, Intravenous; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium Complex; Piperazines; Random Allocation; Rifabutin

2004
Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:5

    Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Colony Count, Microbial; Combinatorial Chemistry Techniques; Disease Models, Animal; Ethambutol; Ethylenediamines; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Tuberculosis; Vero Cells

2005
Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:8

    Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitroimidazoles; Pyrazinamide; Rifampin; Secondary Prevention; Time Factors; Tuberculosis, Pulmonary

2006
Experimental chemotherapy in chronic Mycobacterium avium-intracellulare infection of mice.
    The American review of respiratory disease, 1984, Volume: 129, Issue:3

    Topics: Animals; Antitubercular Agents; Chronic Disease; Cycloserine; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Kanamycin; Liver; Lung; Male; Mice; Mycobacterium avium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Rifampin; Spleen; Time Factors

1984
Ethambutol dose-plasma level correlation studies in guinea pigs.
    The American review of respiratory disease, 1983, Volume: 127, Issue:3

    Topics: Animals; Disease Models, Animal; Ethambutol; Female; Guinea Pigs; Male; Tuberculosis

1983
Activities of clarithromycin, ofloxacin, and clarithromycin plus ethambutol against Mycobacterium simiae in murine model of disseminated infection.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:11

    Topics: Animals; Clarithromycin; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Skin Diseases, Bacterial; Splenic Diseases

1994
Effect of ethambutol on emergence of clarithromycin-resistant Mycobacterium avium complex in the beige mouse model.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Clarithromycin; Disease Models, Animal; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Genes, Bacterial; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis, Site-Directed; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; RNA, Ribosomal, 23S; Spleen

1996
Evaluation of rifalazil in a combination treatment regimen as an alternative to isoniazid-rifampin therapy in a mouse tuberculosis model.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11

    Topics: Animals; Antitubercular Agents; Colony-Forming Units Assay; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Pyrazinamide; Rifampin; Rifamycins; Tuberculosis

2000
In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria.
    International journal of antimicrobial agents, 2001, Volume: 17, Issue:1

    Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Colony Count, Microbial; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Mycobacterium tuberculosis; Tuberculosis

2001
Sparfloxacin, ethambutol, and cortisol receptor inhibitor RU-40 555 treatment for disseminated Mycobacterium avium complex infection of normal C57BL/6 mice.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Feasibility Studies; Female; Fluoroquinolones; Glucocorticoids; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mifepristone; Mycobacterium avium; Quinolones; Receptors, Glucocorticoid; Spleen; Time Factors; Tuberculosis

1992
Activity of clarithromycin against Mycobacterium avium complex infection in beige mice.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Amikacin; Animals; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Clofazimine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Humans; Mice; Mice, Inbred C57BL; Mycobacterium avium; Mycobacterium avium Complex; Quinolones; Rifabutin; Rifampin; Rifamycins; Time Factors; Tuberculosis

1992
[Comparative hepatic toxicity of isoniazid, rifampicin and ethambutol].
    Problemy tuberkuleza, 1991, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Ethambutol; Isoniazid; Liver; Liver Function Tests; Male; Rats; Rifampin

1991
Induced color blindness in goldfish: a behavioral and electrophysiological study.
    Vision research, 1991, Volume: 31, Issue:3

    Topics: Animals; Color Perception; Color Vision Defects; Disease Models, Animal; Electroretinography; Ethambutol; Goldfish; Neurons; Photoreceptor Cells; Sensory Thresholds

1991
The pathogenicity of Mycobacterium tuberculosis during chemotherapy.
    The European respiratory journal, 1990, Volume: 3, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Fluorescent Antibody Technique; Guinea Pigs; Humans; Injections, Subcutaneous; Isoniazid; Mycobacterium tuberculosis; Rifampin; Sputum; Tuberculosis, Pulmonary

1990
[Chemotherapy of so-called atypical mycobacterioses].
    Beitrage zur Klinik und Erforschung der Tuberkulose und der Lungenkrankheiten, 1968, Volume: 137, Issue:2

    Topics: Animals; Antitubercular Agents; Cycloserine; Dapsone; Disease Models, Animal; Drug Synergism; Ethambutol; Ethionamide; Mice; Mycobacterium Infections; Phenylthiourea; Rabbits; Streptomycin; Thioacetazone

1968
[Induction of Mycobacterium infection by introduction of the organisms into the lung through an intratracheal vinyl tube].
    Jikken dobutsu. Experimental animals, 1972, Volume: 21, Issue:2

    Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Dust; Ethambutol; Guinea Pigs; Intubation, Intratracheal; Isoniazid; Kanamycin; Mycobacterium tuberculosis; Silicon Dioxide; Tuberculosis, Pulmonary

1972
[Antitubercular activity and concentrations of rifampicin and ethambutol in the organs].
    Vrachebnoe delo, 1973, Volume: 4

    Topics: Animals; Disease Models, Animal; Ethambutol; Mice; Rifampin; Tuberculosis

1973
The combination of rifampicin and other antituberculous agents in chronic murine tuberculosis.
    Chemotherapy, 1971, Volume: 16, Issue:3

    Topics: Animals; Cell Count; Chronic Disease; Disease Models, Animal; Drug Synergism; Ethambutol; Ethionamide; Isoniazid; Lung; Mice; Placebos; Rifampin; Streptomycin; Tuberculosis

1971