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ethacrynic acid and Uterine Cervical Neoplasms

ethacrynic acid has been researched along with Uterine Cervical Neoplasms in 4 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Uterine Cervical Neoplasms: Tumors or cancer of the UTERINE CERVIX.

Research Excerpts

ExcerptRelevanceReference
"The pineal hormone melatonin has been reported to have in vitro antiproliferative effects on estrogen receptor-positive human breast cancer cell lines at concentrations near to plasma physiological concentrations (1 x 10(-11) to 1 x 10(-9) M)."3.70Effects of melatonin on proliferation of cancer cell lines. ( Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osmak, M1
Papazisis, KT1
Kouretas, D1
Geromichalos, GD1
Sivridis, E1
Tsekreli, OK1
Dimitriadis, KA1
Kortsaris, AH1
Barnette, KG1
Sarkar, MA1
Glover, DD1
Li, P1
Boyd, C1
Lalka, D1
Bezabeh, T1
Mowat, MR1
Jarolim, L1
Greenberg, AH1
Smith, IC1

Other Studies

4 other studies available for ethacrynic acid and Uterine Cervical Neoplasms

ArticleYear
Multifactorial molecular mechanisms are involved in resistance of preirradiated human cervix carcinoma cells to cis-dichlorodiammineplatinum (II) and vincristine.
    Neoplasma, 1993, Volume: 40, Issue:2

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine

1993
Effects of melatonin on proliferation of cancer cell lines.
    Journal of pineal research, 1998, Volume: 25, Issue:4

    Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Repli

1998
Glutathione S-transferase in human endometrium: quantitation and interindividual variability in isoform content.
    Gynecologic and obstetric investigation, 1999, Volume: 47, Issue:2

    Topics: Cytosol; Endometrium; Enzyme Inhibitors; Ethacrynic Acid; Female; Glutathione Transferase; Humans; H

1999
Detection of drug-induced apoptosis and necrosis in human cervical carcinoma cells using 1H NMR spectroscopy.
    Cell death and differentiation, 2001, Volume: 8, Issue:3

    Topics: Apoptosis; Cytochalasin B; Ethacrynic Acid; Female; HeLa Cells; Humans; Magnetic Resonance Spectrosc

2001