ethacrynic acid has been researched along with Uterine Cervical Neoplasms in 4 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Uterine Cervical Neoplasms: Tumors or cancer of the UTERINE CERVIX.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pineal hormone melatonin has been reported to have in vitro antiproliferative effects on estrogen receptor-positive human breast cancer cell lines at concentrations near to plasma physiological concentrations (1 x 10(-11) to 1 x 10(-9) M)." | 3.70 | Effects of melatonin on proliferation of cancer cell lines. ( Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osmak, M | 1 |
| Papazisis, KT | 1 |
| Kouretas, D | 1 |
| Geromichalos, GD | 1 |
| Sivridis, E | 1 |
| Tsekreli, OK | 1 |
| Dimitriadis, KA | 1 |
| Kortsaris, AH | 1 |
| Barnette, KG | 1 |
| Sarkar, MA | 1 |
| Glover, DD | 1 |
| Li, P | 1 |
| Boyd, C | 1 |
| Lalka, D | 1 |
| Bezabeh, T | 1 |
| Mowat, MR | 1 |
| Jarolim, L | 1 |
| Greenberg, AH | 1 |
| Smith, IC | 1 |
4 other studies available for ethacrynic acid and Uterine Cervical Neoplasms
| Article | Year |
|---|---|
Multifactorial molecular mechanisms are involved in resistance of preirradiated human cervix carcinoma cells to cis-dichlorodiammineplatinum (II) and vincristine.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine | 1993 |
Effects of melatonin on proliferation of cancer cell lines.
Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Repli | 1998 |
Glutathione S-transferase in human endometrium: quantitation and interindividual variability in isoform content.
Topics: Cytosol; Endometrium; Enzyme Inhibitors; Ethacrynic Acid; Female; Glutathione Transferase; Humans; H | 1999 |
Detection of drug-induced apoptosis and necrosis in human cervical carcinoma cells using 1H NMR spectroscopy.
Topics: Apoptosis; Cytochalasin B; Ethacrynic Acid; Female; HeLa Cells; Humans; Magnetic Resonance Spectrosc | 2001 |