ethacrynic acid has been researched along with Uremia in 12 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
BERNSTEIN, A | 1 |
ODZE, M | 1 |
CREWS, A | 1 |
SIMON, F | 1 |
Sherlock, S | 1 |
Senewiratne, B | 1 |
Scott, A | 1 |
Walker, JG | 1 |
Pillay, VK | 2 |
Schwartz, FD | 2 |
Aimi, K | 1 |
Kark, RM | 2 |
Hanzelik, E | 1 |
Peppercorn, M | 1 |
Kim, KE | 1 |
Onesti, G | 1 |
Swartz, C | 1 |
Coodley, EL | 1 |
Garfield, A | 1 |
Guiterrez, J | 1 |
Platt, B | 1 |
Jaros, Z | 1 |
Leiter, L | 1 |
Meriwether, WD | 1 |
Mangi, RJ | 1 |
Serpick, AA | 1 |
Mathog, RH | 1 |
Klein, WJ | 1 |
Welt, LG | 1 |
2 reviews available for ethacrynic acid and Uremia
Article | Year |
---|---|
[Edecrin].
Topics: Animals; Chickens; Diuresis; Ethacrynic Acid; Exercise Test; Glucose; Heart Failure; Humans; Liver C | 1970 |
Combinations of diuretics in the treatment of edema.
Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu | 1970 |
10 other studies available for ethacrynic acid and Uremia
Article | Year |
---|---|
ETHACRYNIC ACID: A NEW POTENT DIURETIC.
Topics: Alkalosis; Blood Chemical Analysis; Blood Urea Nitrogen; Body Weight; Digitalis Glycosides; Diuresis | 1965 |
Complications of diuretic therapy in hepatic cirrhosis.
Topics: Chlorothiazide; Diuretics; Ethacrynic Acid; Furosemide; Hepatic Encephalopathy; Humans; Hypokalemia; | 1966 |
Transient and permanent deafness following treatment with ethacrynic acid in renal failure.
Topics: Adult; Amphetamine; Aortic Valve Insufficiency; Aspartate Aminotransferases; Blood Urea Nitrogen; Ca | 1969 |
Deafness after ethacrynic acid.
Topics: Deafness; Ethacrynic Acid; Humans; Male; Middle Aged; Uremia | 1969 |
Problems in therapy for the hypertensive patient.
Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic | 1973 |
Nondialytic management of chronic uremia.
Topics: Administration, Oral; Adult; Blood Urea Nitrogen; Chronic Disease; Creatinine; Diuresis; Diuretics; | 1973 |
Deafness following standard intravenous dose of ethacrynic acid.
Topics: Anti-Bacterial Agents; Anuria; Deafness; Diuresis; Drug Synergism; Ethacrynic Acid; Female; Humans; | 1971 |
Ethacrynic acid: its usefulness and untoward effects.
Topics: Adult; Aged; Cochlea; Deafness; Ear Diseases; Ethacrynic Acid; Female; Hallucinations; Humans; Injec | 1970 |
Ototoxicity of ethacrynic acid and aminoglycoside antibiotics in uremia.
Topics: Acute Kidney Injury; Adult; Amino Sugars; Anti-Bacterial Agents; Audiometry; Deafness; Ethacrynic Ac | 1969 |
A further evaluation of erythrocyte sodium transport in control subjects and patients with uremia.
Topics: Biological Transport, Active; Chlorides; Diffusion; Erythrocytes; Ethacrynic Acid; Humans; Ouabain; | 1969 |