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ethacrynic acid and Uremia

ethacrynic acid has been researched along with Uremia in 12 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BERNSTEIN, A1
ODZE, M1
CREWS, A1
SIMON, F1
Sherlock, S1
Senewiratne, B1
Scott, A1
Walker, JG1
Pillay, VK2
Schwartz, FD2
Aimi, K1
Kark, RM2
Hanzelik, E1
Peppercorn, M1
Kim, KE1
Onesti, G1
Swartz, C1
Coodley, EL1
Garfield, A1
Guiterrez, J1
Platt, B1
Jaros, Z1
Leiter, L1
Meriwether, WD1
Mangi, RJ1
Serpick, AA1
Mathog, RH1
Klein, WJ1
Welt, LG1

Reviews

2 reviews available for ethacrynic acid and Uremia

ArticleYear
[Edecrin].
    Casopis lekaru ceskych, 1970, Volume: 109, Issue:14

    Topics: Animals; Chickens; Diuresis; Ethacrynic Acid; Exercise Test; Glucose; Heart Failure; Humans; Liver C

1970
Combinations of diuretics in the treatment of edema.
    American heart journal, 1970, Volume: 80, Issue:3

    Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu

1970

Other Studies

10 other studies available for ethacrynic acid and Uremia

ArticleYear
ETHACRYNIC ACID: A NEW POTENT DIURETIC.
    The American journal of the medical sciences, 1965, Volume: 249

    Topics: Alkalosis; Blood Chemical Analysis; Blood Urea Nitrogen; Body Weight; Digitalis Glycosides; Diuresis

1965
Complications of diuretic therapy in hepatic cirrhosis.
    Lancet (London, England), 1966, May-14, Volume: 1, Issue:7446

    Topics: Chlorothiazide; Diuretics; Ethacrynic Acid; Furosemide; Hepatic Encephalopathy; Humans; Hypokalemia;

1966
Transient and permanent deafness following treatment with ethacrynic acid in renal failure.
    Lancet (London, England), 1969, Jan-11, Volume: 1, Issue:7585

    Topics: Adult; Amphetamine; Aortic Valve Insufficiency; Aspartate Aminotransferases; Blood Urea Nitrogen; Ca

1969
Deafness after ethacrynic acid.
    Lancet (London, England), 1969, Feb-22, Volume: 1, Issue:7591

    Topics: Deafness; Ethacrynic Acid; Humans; Male; Middle Aged; Uremia

1969
Problems in therapy for the hypertensive patient.
    Geriatrics, 1973, Volume: 28, Issue:3

    Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic

1973
Nondialytic management of chronic uremia.
    JAMA, 1973, May-07, Volume: 224, Issue:6

    Topics: Administration, Oral; Adult; Blood Urea Nitrogen; Chronic Disease; Creatinine; Diuresis; Diuretics;

1973
Deafness following standard intravenous dose of ethacrynic acid.
    JAMA, 1971, May-03, Volume: 216, Issue:5

    Topics: Anti-Bacterial Agents; Anuria; Deafness; Diuresis; Drug Synergism; Ethacrynic Acid; Female; Humans;

1971
Ethacrynic acid: its usefulness and untoward effects.
    American heart journal, 1970, Volume: 79, Issue:3

    Topics: Adult; Aged; Cochlea; Deafness; Ear Diseases; Ethacrynic Acid; Female; Hallucinations; Humans; Injec

1970
Ototoxicity of ethacrynic acid and aminoglycoside antibiotics in uremia.
    The New England journal of medicine, 1969, May-29, Volume: 280, Issue:22

    Topics: Acute Kidney Injury; Adult; Amino Sugars; Anti-Bacterial Agents; Audiometry; Deafness; Ethacrynic Ac

1969
A further evaluation of erythrocyte sodium transport in control subjects and patients with uremia.
    Nephron, 1969, Volume: 6, Issue:3

    Topics: Biological Transport, Active; Chlorides; Diffusion; Erythrocytes; Ethacrynic Acid; Humans; Ouabain;

1969