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ethacrynic acid and Protein-Energy Malnutrition

ethacrynic acid has been researched along with Protein-Energy Malnutrition in 1 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Protein-Energy Malnutrition: The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.

Research Excerpts

ExcerptRelevanceReference
" Gentamicin in combination with 20 mg ethacrynic acid/kg body weight produced a hearing loss of 95 dB in animals on a low protein diet and 12 dB in animals on a full protein diet."3.69[Reduced nutritional status enhances ototoxicity]. ( Lautermann, J; Schacht, J, 1995)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lautermann, J1
Schacht, J1

Other Studies

1 other study available for ethacrynic acid and Protein-Energy Malnutrition

ArticleYear
[Reduced nutritional status enhances ototoxicity].
    Laryngo- rhino- otologie, 1995, Volume: 74, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Auditory Pathways; Auditory Threshold; Body W

1995