ethacrynic acid has been researched along with Obesity in 7 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (85.71) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
Authors | Studies |
---|---|
Cui, Z | 1 |
Liu, Y | 1 |
Wan, W | 1 |
Xu, Y | 1 |
Hu, Y | 1 |
Ding, M | 1 |
Dou, X | 1 |
Wang, R | 1 |
Li, H | 1 |
Meng, Y | 1 |
Li, W | 1 |
Jiang, W | 1 |
Li, Z | 1 |
Li, Y | 1 |
Tan, M | 1 |
Ma, DK | 1 |
Ding, Y | 1 |
Liu, JO | 1 |
Luo, C | 1 |
Yu, B | 1 |
Tang, Q | 1 |
Dang, Y | 1 |
Laroche, C | 1 |
Grégoire, J | 1 |
Farel, H | 1 |
Fritel, D | 1 |
Milliez, P | 1 |
Sterz, H | 1 |
Felman, D | 1 |
Theoleyre, J | 1 |
Dupoizat, H | 1 |
Wallnöfer, H | 1 |
Hanusch, M | 1 |
Cicconetti, C | 1 |
Cantera, N | 1 |
1 trial available for ethacrynic acid and Obesity
Article | Year |
---|---|
[Clinical study of a new diuretic: ethacrynic acid (M.K. 595)].
Topics: Adult; Aged; Clinical Trials as Topic; Ethacrynic Acid; Female; Heart Failure; Humans; Hypertension; | 1965 |
6 other studies available for ethacrynic acid and Obesity
Article | Year |
---|---|
Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes.
Topics: 3T3 Cells; Adipocytes, White; Adipose Tissue, White; Animals; Ethacrynic Acid; Glutathione Transfera | 2021 |
[Clinical trials of ethacrynic acid].
Topics: Adult; Ascites; Edema; Ethacrynic Acid; Female; Heart Failure; Humans; Liver Cirrhosis; Male; Middle | 1967 |
[Clinical studies on the diuretic effect of ethacrynic acid].
Topics: Diabetes Complications; Diuresis; Edema; Electrolytes; Ethacrynic Acid; Heart Failure; Humans; Hypon | 1969 |
[Trial of ethacrynic acid in treatment of excessive weight gain and arterial hypertension in pregnancy].
Topics: Adult; Arteries; Body Weight; Diabetes Mellitus; Ethacrynic Acid; Female; Humans; Hypertension; Infa | 1967 |
[Diuresis with edecrin].
Topics: Adult; Aged; Diabetes Mellitus; Diuretics; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirr | 1968 |
[Clinical experience with the use of a new drug: "ethacrynic acid"].
Topics: Adult; Aged; Ascites; Diuresis; Edema; Electrolytes; Ethacrynic Acid; Female; Heart Failure; Humans; | 1969 |