Page last updated: 2024-10-26

ethacrynic acid and Obesity

ethacrynic acid has been researched along with Obesity in 7 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Cui, Z1
Liu, Y1
Wan, W1
Xu, Y1
Hu, Y1
Ding, M1
Dou, X1
Wang, R1
Li, H1
Meng, Y1
Li, W1
Jiang, W1
Li, Z1
Li, Y1
Tan, M1
Ma, DK1
Ding, Y1
Liu, JO1
Luo, C1
Yu, B1
Tang, Q1
Dang, Y1
Laroche, C1
Grégoire, J1
Farel, H1
Fritel, D1
Milliez, P1
Sterz, H1
Felman, D1
Theoleyre, J1
Dupoizat, H1
Wallnöfer, H1
Hanusch, M1
Cicconetti, C1
Cantera, N1

Trials

1 trial available for ethacrynic acid and Obesity

ArticleYear
[Clinical study of a new diuretic: ethacrynic acid (M.K. 595)].
    Semaine therapeutique, 1965, Volume: 41, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Ethacrynic Acid; Female; Heart Failure; Humans; Hypertension;

1965

Other Studies

6 other studies available for ethacrynic acid and Obesity

ArticleYear
Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes.
    Protein & cell, 2021, Volume: 12, Issue:6

    Topics: 3T3 Cells; Adipocytes, White; Adipose Tissue, White; Animals; Ethacrynic Acid; Glutathione Transfera

2021
[Clinical trials of ethacrynic acid].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1967, Jun-08, Volume: 43, Issue:28

    Topics: Adult; Ascites; Edema; Ethacrynic Acid; Female; Heart Failure; Humans; Liver Cirrhosis; Male; Middle

1967
[Clinical studies on the diuretic effect of ethacrynic acid].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1969, Volume: 50, Issue:1

    Topics: Diabetes Complications; Diuresis; Edema; Electrolytes; Ethacrynic Acid; Heart Failure; Humans; Hypon

1969
[Trial of ethacrynic acid in treatment of excessive weight gain and arterial hypertension in pregnancy].
    Lyon medical, 1967, May-07, Volume: 217, Issue:19

    Topics: Adult; Arteries; Body Weight; Diabetes Mellitus; Ethacrynic Acid; Female; Humans; Hypertension; Infa

1967
[Diuresis with edecrin].
    Wiener medizinische Wochenschrift (1946), 1968, Apr-20, Volume: 118, Issue:16

    Topics: Adult; Aged; Diabetes Mellitus; Diuretics; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirr

1968
[Clinical experience with the use of a new drug: "ethacrynic acid"].
    Il Policlinico. Sezione pratica, 1969, Volume: 76, Issue:3

    Topics: Adult; Aged; Ascites; Diuresis; Edema; Electrolytes; Ethacrynic Acid; Female; Heart Failure; Humans;

1969