ethacrynic acid and Necrosis
ethacrynic acid has been researched along with Necrosis in 4 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Wu, W | 1 |
Zhu, H | 1 |
Fu, Y | 1 |
Shen, W | 1 |
Miao, K | 1 |
Hong, M | 1 |
Xu, W | 1 |
Fan, L | 1 |
Young, KH | 1 |
Liu, P | 1 |
Li, J | 1 |
Bezabeh, T | 1 |
Mowat, MR | 1 |
Jarolim, L | 1 |
Greenberg, AH | 1 |
Smith, IC | 1 |
Selye, H | 2 |
Somogyi, A | 1 |
Savoie, L | 1 |
Other Studies
4 other studies available for ethacrynic acid and Necrosis
Article | Year |
---|---|
High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Deubiquitinating Enzyme CYLD; Ethacrynic Acid; Female; Ge | 2016 |
Detection of drug-induced apoptosis and necrosis in human cervical carcinoma cells using 1H NMR spectroscopy.
Topics: Apoptosis; Cytochalasin B; Ethacrynic Acid; Female; HeLa Cells; Humans; Magnetic Resonance Spectrosc | 2001 |
Prevention of stress-induced cardiac necrosis by amiloride.
Topics: Animals; Diuretics; Ethacrynic Acid; Female; Heart Diseases; Hydrochlorothiazide; Immobilization; My | 1969 |
Effect of various diuretics upon experimental cardiac necrosis.
Topics: Adrenal Cortex Hormones; Animals; Diuretics; Ethacrynic Acid; Guanidines; Heart Diseases; Hydrochlor | 1969 |