Page last updated: 2024-10-26

ethacrynic acid and Necrosis

ethacrynic acid has been researched along with Necrosis in 4 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, W1
Zhu, H1
Fu, Y1
Shen, W1
Miao, K1
Hong, M1
Xu, W1
Fan, L1
Young, KH1
Liu, P1
Li, J1
Bezabeh, T1
Mowat, MR1
Jarolim, L1
Greenberg, AH1
Smith, IC1
Selye, H2
Somogyi, A1
Savoie, L1

Other Studies

4 other studies available for ethacrynic acid and Necrosis

ArticleYear
High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid.
    Oncotarget, 2016, Apr-19, Volume: 7, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Deubiquitinating Enzyme CYLD; Ethacrynic Acid; Female; Ge

2016
Detection of drug-induced apoptosis and necrosis in human cervical carcinoma cells using 1H NMR spectroscopy.
    Cell death and differentiation, 2001, Volume: 8, Issue:3

    Topics: Apoptosis; Cytochalasin B; Ethacrynic Acid; Female; HeLa Cells; Humans; Magnetic Resonance Spectrosc

2001
Prevention of stress-induced cardiac necrosis by amiloride.
    Angiologica, 1969, Volume: 6, Issue:5

    Topics: Animals; Diuretics; Ethacrynic Acid; Female; Heart Diseases; Hydrochlorothiazide; Immobilization; My

1969
Effect of various diuretics upon experimental cardiac necrosis.
    American heart journal, 1969, Volume: 77, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Diuretics; Ethacrynic Acid; Guanidines; Heart Diseases; Hydrochlor

1969
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