ethacrynic acid has been researched along with Muscle Relaxation in 12 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kıroğlu, OE | 1 |
| Aydinoglu, F | 1 |
| Oğülener, N | 3 |
| Ergün, Y | 2 |
| Triguero, D | 1 |
| González-Herreros, M | 1 |
| Costa, G | 1 |
| García-Pascual, A | 1 |
| Marinkovich, GA | 1 |
| Pichoff, BE | 1 |
| Iwamoto, LM | 1 |
| Dressel, MV | 1 |
| Nakamura, KT | 1 |
| Li, CG | 1 |
| Brosch, SF | 1 |
| Rand, MJ | 1 |
| Kenkare, SR | 1 |
| Benet, LZ | 1 |
| Greenwood, IA | 1 |
| Hogg, RC | 1 |
| Large, WA | 1 |
| Lovren, F | 1 |
| Triggle, CR | 1 |
| Kishen, R | 1 |
| Pleuvry, BJ | 1 |
| Rapoport, RM | 1 |
| Murad, F | 1 |
| Gruetter, CA | 1 |
| Lemke, SM | 1 |
12 other studies available for ethacrynic acid and Muscle Relaxation
| Article | Year |
|---|---|
The effects of thiol modulators on nitrergic nerve- and S-nitrosothiols-induced relaxation in duodenum.
Topics: Analysis of Variance; Animals; Buthionine Sulfoximine; Cysteine; Diuretics; Dose-Response Relationsh | 2013 |
A putative role for S-nitrosoglutathione as the source of nitric oxide in photorelaxation of the mouse gastric fundus.
Topics: Acetylcysteine; Animals; Cysteine; Diamide; Enzyme Inhibitors; Ethacrynic Acid; Female; Gastric Fund | 2002 |
Selective modifiers of glutathione prevent restoration of photorelaxations in mouse gastric fundus.
Topics: Animals; Diamide; Electric Stimulation; Ethacrynic Acid; Female; Gastric Fundus; Glutathione; Humans | 2005 |
Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation.
Topics: Animals; Animals, Newborn; Buthionine Sulfoximine; Citrulline; Electric Stimulation; Endothelium, Va | 2008 |
Acute hyperoxic injury attenuates the relaxing effects of "loop" diuretics and salbutamol on large airways of newborn guinea pigs.
Topics: Albuterol; Animals; Animals, Newborn; Bronchi; Bronchodilator Agents; Diuretics; Ethacrynic Acid; Fe | 1995 |
Inhibition by ethacrynic acid of NO-mediated relaxations of the rat anococcygeus muscle.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cysteine; Drug Interactions; Electric Stimulation; Et | 1994 |
Effect of ethacrynic acid, a glutathione-S-transferase inhibitor, on nitroglycerin-mediated cGMP elevation and vasorelaxation of rabbit aortic strips.
Topics: Animals; Aorta; Cyclic GMP; Ethacrynic Acid; Glutathione Transferase; In Vitro Techniques; Muscle Re | 1993 |
Effect of frusemide, ethacrynic acid and indanyloxyacetic acid on spontaneous Ca-activated currents in rabbit portal vein smooth muscle cells.
Topics: Animals; Calcium; Chloride Channels; Diuretics; Ethacrynic Acid; Female; Furosemide; Glycolates; In | 1995 |
Involvement of nitrosothiols, nitric oxide and voltage-gated K+ channels in photorelaxation of vascular smooth muscle.
Topics: Benzoates; Ethacrynic Acid; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Imidazoles; In Vitr | 1998 |
Some actions of sodium nitroprusside and glyceryl trinitrate on guinea-pig isolated trachealis muscle.
Topics: Aminophylline; Animals; Ethacrynic Acid; Female; Ferricyanides; Guinea Pigs; In Vitro Techniques; Is | 1985 |
Effects of ethacrynic acid and cystamine on sodium nitroprusside-induced relaxation, cyclic GMP levels and guanylate cyclase activity in rat aorta.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Cystamine; | 1988 |
Effects of sulfhydryl reagents on nitroglycerin-induced relaxation of bovine coronary artery.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Ethacrynic Acid; Ethylmaleimide; In Vitro Techniques; | 1986 |