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ethacrynic acid and Muscle Relaxation

ethacrynic acid has been researched along with Muscle Relaxation in 12 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's5 (41.67)18.2507
2000's3 (25.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kıroğlu, OE1
Aydinoglu, F1
Oğülener, N3
Ergün, Y2
Triguero, D1
González-Herreros, M1
Costa, G1
García-Pascual, A1
Marinkovich, GA1
Pichoff, BE1
Iwamoto, LM1
Dressel, MV1
Nakamura, KT1
Li, CG1
Brosch, SF1
Rand, MJ1
Kenkare, SR1
Benet, LZ1
Greenwood, IA1
Hogg, RC1
Large, WA1
Lovren, F1
Triggle, CR1
Kishen, R1
Pleuvry, BJ1
Rapoport, RM1
Murad, F1
Gruetter, CA1
Lemke, SM1

Other Studies

12 other studies available for ethacrynic acid and Muscle Relaxation

ArticleYear
The effects of thiol modulators on nitrergic nerve- and S-nitrosothiols-induced relaxation in duodenum.
    Journal of basic and clinical physiology and pharmacology, 2013, Volume: 24, Issue:2

    Topics: Analysis of Variance; Animals; Buthionine Sulfoximine; Cysteine; Diuretics; Dose-Response Relationsh

2013
A putative role for S-nitrosoglutathione as the source of nitric oxide in photorelaxation of the mouse gastric fundus.
    European journal of pharmacology, 2002, Aug-30, Volume: 450, Issue:3

    Topics: Acetylcysteine; Animals; Cysteine; Diamide; Enzyme Inhibitors; Ethacrynic Acid; Female; Gastric Fund

2002
Selective modifiers of glutathione prevent restoration of photorelaxations in mouse gastric fundus.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:4

    Topics: Animals; Diamide; Electric Stimulation; Ethacrynic Acid; Female; Gastric Fundus; Glutathione; Humans

2005
Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 455, Issue:4

    Topics: Animals; Animals, Newborn; Buthionine Sulfoximine; Citrulline; Electric Stimulation; Endothelium, Va

2008
Acute hyperoxic injury attenuates the relaxing effects of "loop" diuretics and salbutamol on large airways of newborn guinea pigs.
    Pediatric research, 1995, Volume: 38, Issue:3

    Topics: Albuterol; Animals; Animals, Newborn; Bronchi; Bronchodilator Agents; Diuretics; Ethacrynic Acid; Fe

1995
Inhibition by ethacrynic acid of NO-mediated relaxations of the rat anococcygeus muscle.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cysteine; Drug Interactions; Electric Stimulation; Et

1994
Effect of ethacrynic acid, a glutathione-S-transferase inhibitor, on nitroglycerin-mediated cGMP elevation and vasorelaxation of rabbit aortic strips.
    Biochemical pharmacology, 1993, Jul-20, Volume: 46, Issue:2

    Topics: Animals; Aorta; Cyclic GMP; Ethacrynic Acid; Glutathione Transferase; In Vitro Techniques; Muscle Re

1993
Effect of frusemide, ethacrynic acid and indanyloxyacetic acid on spontaneous Ca-activated currents in rabbit portal vein smooth muscle cells.
    British journal of pharmacology, 1995, Volume: 115, Issue:5

    Topics: Animals; Calcium; Chloride Channels; Diuretics; Ethacrynic Acid; Female; Furosemide; Glycolates; In

1995
Involvement of nitrosothiols, nitric oxide and voltage-gated K+ channels in photorelaxation of vascular smooth muscle.
    European journal of pharmacology, 1998, Apr-24, Volume: 347, Issue:2-3

    Topics: Benzoates; Ethacrynic Acid; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Imidazoles; In Vitr

1998
Some actions of sodium nitroprusside and glyceryl trinitrate on guinea-pig isolated trachealis muscle.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:7

    Topics: Aminophylline; Animals; Ethacrynic Acid; Female; Ferricyanides; Guinea Pigs; In Vitro Techniques; Is

1985
Effects of ethacrynic acid and cystamine on sodium nitroprusside-induced relaxation, cyclic GMP levels and guanylate cyclase activity in rat aorta.
    General pharmacology, 1988, Volume: 19, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Cystamine;

1988
Effects of sulfhydryl reagents on nitroglycerin-induced relaxation of bovine coronary artery.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:11

    Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Ethacrynic Acid; Ethylmaleimide; In Vitro Techniques;

1986