ethacrynic acid has been researched along with Milk-Alkali Syndrome in 13 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The combined venodilatory and natriuretic effects of bumetanide, furosemide and ethacrynic acid relieve congestive symptoms in pulmonary edema." | 4.77 | Diuretic use in critical care. ( Chusid, P; Narins, RG, 1986) |
| " Less convincing, but suggestive evidence exists for: 1-asparaginase, iatrogenic hypercalcemia, chlorthalidine, corticosteroids, ethacrynic acid, phenformin, and procainamide." | 4.76 | Drug-induced pancreatitis: a critical review. ( Kern, F; Mallory, A, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sejersted, OM | 1 |
| Steen, PA | 1 |
| Kiil, F | 1 |
| Courvoisier, B | 1 |
| Mallory, A | 1 |
| Kern, F | 1 |
| Hart, M | 1 |
| Windle, J | 1 |
| McHale, M | 1 |
| Grissom, R | 1 |
| Steiner, RW | 1 |
| Blantz, RC | 1 |
| Krumlovsky, FA | 1 |
| del Greco, F | 1 |
| Narins, RG | 1 |
| Chusid, P | 1 |
| Mason, DT | 1 |
| Zelis, R | 1 |
| Lee, G | 1 |
| Hughes, JL | 1 |
| Spann, JF | 1 |
| Amsterdam, EA | 1 |
| Lenhard, RE | 1 |
| Deftos, LJ | 1 |
| Neer, R | 1 |
| Martinez-Maldonado, M | 1 |
| Dustan, HR | 1 |
| Tarazi, RC | 1 |
| Bravo, EL | 1 |
| Walser, M | 1 |
5 reviews available for ethacrynic acid and Milk-Alkali Syndrome
| Article | Year |
|---|---|
Drug-induced pancreatitis: a critical review.
Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Ch | 1980 |
Diuretic use in critical care.
Topics: Biological Transport; Calcium; Critical Care; Diuretics; Ethacrynic Acid; Extracellular Space; Human | 1986 |
Current concepts and treatment of digitalis toxicity.
Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Binding Sites; Biological Transport; Calcium; Catec | 1971 |
Medical management of the hypercalcemia of malignancy.
Topics: Bone Neoplasms; Calcitonin; Citrates; Edetic Acid; Ethacrynic Acid; Furosemide; Glucocorticoids; Hum | 1974 |
Treatment of hypercalcemias.
Topics: Administration, Oral; Calcitonin; Calcium, Dietary; Citrates; Diuretics; Edetic Acid; Ethacrynic Aci | 1970 |
1 trial available for ethacrynic acid and Milk-Alkali Syndrome
| Article | Year |
|---|---|
Clinical case records in chemotherapy: the management of hypercalcemia complicating cancer.
Topics: Adult; Aged; Breast Neoplasms; Calcium; Citrates; Clinical Trials as Topic; Cyclophosphamide; Edetic | 1971 |
7 other studies available for ethacrynic acid and Milk-Alkali Syndrome
| Article | Year |
|---|---|
Inhibition of transcellular NaCl reabsorption in dog kidneys during hypercalcemia.
Topics: Animals; Bicarbonates; Calcium Chloride; Dogs; Ethacrynic Acid; Female; Glomerular Filtration Rate; | 1984 |
[Treatment of hypercalcemias].
Topics: Adrenal Cortex Hormones; Bone Neoplasms; Calcitonin; Edetic Acid; Ethacrynic Acid; Furosemide; Glome | 1981 |
Milk-alkali syndrome and hypercalcemia: a case report.
Topics: Aged; Calcium; Ethacrynic Acid; Furosemide; Humans; Hypercalcemia; Male | 1982 |
The use of diuretics in nonedematous conditions.
Topics: Acute Kidney Injury; Benzothiadiazines; Calcium; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hyp | 1979 |
Diuretic agents. Mechanisms of action and clinical uses.
Topics: Acute Kidney Injury; Benzothiadiazines; Carbonic Anhydrase Inhibitors; Diabetes Insipidus; Diuretics | 1976 |
Electrolyte disturbances resulting from diuretic therapy.
Topics: Acetazolamide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypercalcemia; Hypokalemia; Hyponatre | 1973 |
Diuretic and diet treatment of hypertension.
Topics: Benzothiadiazines; Blood Volume; Chlorthalidone; Creatinine; Diet, Sodium-Restricted; Diuretics; Eth | 1974 |