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ethacrynic acid and Milk-Alkali Syndrome

ethacrynic acid has been researched along with Milk-Alkali Syndrome in 13 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Research Excerpts

ExcerptRelevanceReference
" The combined venodilatory and natriuretic effects of bumetanide, furosemide and ethacrynic acid relieve congestive symptoms in pulmonary edema."4.77Diuretic use in critical care. ( Chusid, P; Narins, RG, 1986)
" Less convincing, but suggestive evidence exists for: 1-asparaginase, iatrogenic hypercalcemia, chlorthalidine, corticosteroids, ethacrynic acid, phenformin, and procainamide."4.76Drug-induced pancreatitis: a critical review. ( Kern, F; Mallory, A, 1980)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199013 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sejersted, OM1
Steen, PA1
Kiil, F1
Courvoisier, B1
Mallory, A1
Kern, F1
Hart, M1
Windle, J1
McHale, M1
Grissom, R1
Steiner, RW1
Blantz, RC1
Krumlovsky, FA1
del Greco, F1
Narins, RG1
Chusid, P1
Mason, DT1
Zelis, R1
Lee, G1
Hughes, JL1
Spann, JF1
Amsterdam, EA1
Lenhard, RE1
Deftos, LJ1
Neer, R1
Martinez-Maldonado, M1
Dustan, HR1
Tarazi, RC1
Bravo, EL1
Walser, M1

Reviews

5 reviews available for ethacrynic acid and Milk-Alkali Syndrome

ArticleYear
Drug-induced pancreatitis: a critical review.
    Gastroenterology, 1980, Volume: 78, Issue:4

    Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Ch

1980
Diuretic use in critical care.
    The American journal of cardiology, 1986, Jan-24, Volume: 57, Issue:2

    Topics: Biological Transport; Calcium; Critical Care; Diuretics; Ethacrynic Acid; Extracellular Space; Human

1986
Current concepts and treatment of digitalis toxicity.
    The American journal of cardiology, 1971, Volume: 27, Issue:5

    Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Binding Sites; Biological Transport; Calcium; Catec

1971
Medical management of the hypercalcemia of malignancy.
    Annual review of medicine, 1974, Volume: 25, Issue:0

    Topics: Bone Neoplasms; Calcitonin; Citrates; Edetic Acid; Ethacrynic Acid; Furosemide; Glucocorticoids; Hum

1974
Treatment of hypercalcemias.
    Modern treatment, 1970, Volume: 7, Issue:3

    Topics: Administration, Oral; Calcitonin; Calcium, Dietary; Citrates; Diuretics; Edetic Acid; Ethacrynic Aci

1970

Trials

1 trial available for ethacrynic acid and Milk-Alkali Syndrome

ArticleYear
Clinical case records in chemotherapy: the management of hypercalcemia complicating cancer.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Calcium; Citrates; Clinical Trials as Topic; Cyclophosphamide; Edetic

1971

Other Studies

7 other studies available for ethacrynic acid and Milk-Alkali Syndrome

ArticleYear
Inhibition of transcellular NaCl reabsorption in dog kidneys during hypercalcemia.
    Acta physiologica Scandinavica, 1984, Volume: 120, Issue:4

    Topics: Animals; Bicarbonates; Calcium Chloride; Dogs; Ethacrynic Acid; Female; Glomerular Filtration Rate;

1984
[Treatment of hypercalcemias].
    Schweizerische medizinische Wochenschrift, 1981, Dec-05, Volume: 111, Issue:49

    Topics: Adrenal Cortex Hormones; Bone Neoplasms; Calcitonin; Edetic Acid; Ethacrynic Acid; Furosemide; Glome

1981
Milk-alkali syndrome and hypercalcemia: a case report.
    The Nebraska medical journal, 1982, Volume: 67, Issue:5

    Topics: Aged; Calcium; Ethacrynic Acid; Furosemide; Humans; Hypercalcemia; Male

1982
The use of diuretics in nonedematous conditions.
    Medical times, 1979, Volume: 107, Issue:12

    Topics: Acute Kidney Injury; Benzothiadiazines; Calcium; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hyp

1979
Diuretic agents. Mechanisms of action and clinical uses.
    Postgraduate medicine, 1976, Volume: 59, Issue:4

    Topics: Acute Kidney Injury; Benzothiadiazines; Carbonic Anhydrase Inhibitors; Diabetes Insipidus; Diuretics

1976
Electrolyte disturbances resulting from diuretic therapy.
    Texas medicine, 1973, Volume: 69, Issue:7

    Topics: Acetazolamide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypercalcemia; Hypokalemia; Hyponatre

1973
Diuretic and diet treatment of hypertension.
    Archives of internal medicine, 1974, Volume: 133, Issue:6

    Topics: Benzothiadiazines; Blood Volume; Chlorthalidone; Creatinine; Diet, Sodium-Restricted; Diuretics; Eth

1974