ethacrynic acid has been researched along with Malaria, Falciparum in 1 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mangoyi, R | 1 |
| Hayeshi, R | 1 |
| Ngadjui, B | 1 |
| Ngandeu, F | 1 |
| Bezabih, M | 1 |
| Abegaz, B | 1 |
| Razafimahefa, S | 1 |
| Rasoanaivo, P | 1 |
| Mukanganyama, S | 1 |
1 other study available for ethacrynic acid and Malaria, Falciparum
| Article | Year |
|---|---|
Glutathione transferase from Plasmodium falciparum--interaction with malagashanine and selected plant natural products.
Topics: Alkaloids; Biological Products; Chloroquine; Coumarins; Curcumin; Dinitrochlorobenzene; Drug Discove | 2010 |