ethacrynic acid has been researched along with Lymphoma in 4 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combined apoptotic effects of ATO plus ethacrynic acid were tested in non-APL leukemia and lymphoma cell lines." | 7.78 | Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1. ( Gabrilove, J; Jing, Y; Liu, C; Wang, R; Waxman, S; Xia, L; Zhao, G, 2012) |
| "The combined apoptotic effects of ATO plus ethacrynic acid were tested in non-APL leukemia and lymphoma cell lines." | 3.78 | Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1. ( Gabrilove, J; Jing, Y; Liu, C; Wang, R; Waxman, S; Xia, L; Zhao, G, 2012) |
| "3 microM, ethacrynic acid was toxic to 8 of 24 (33%) tumor specimens studied." | 1.28 | Enhancement of anthracycline and alkylator cytotoxicity by ethacrynic acid in primary cultures of human tissues. ( Kern, DH; Messenger, JC; Nagourney, RA; Weisenthal, LM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, M | 1 |
| Sievers, E | 1 |
| Endo, T | 1 |
| Lu, D | 1 |
| Carson, D | 1 |
| Schmidt-Wolf, IG | 1 |
| Wang, R | 1 |
| Liu, C | 1 |
| Xia, L | 1 |
| Zhao, G | 1 |
| Gabrilove, J | 1 |
| Waxman, S | 1 |
| Jing, Y | 1 |
| Nagourney, RA | 1 |
| Messenger, JC | 1 |
| Kern, DH | 1 |
| Weisenthal, LM | 1 |
| Hamburger, JI | 1 |
4 other studies available for ethacrynic acid and Lymphoma
| Article | Year |
|---|---|
Targeting Wnt pathway in lymphoma and myeloma cells.
Topics: Antifungal Agents; Apoptosis; Cell Line, Tumor; Ciclopirox; Diuretics; Ethacrynic Acid; Humans; Lymp | 2009 |
Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Catalase; Cell Line, Tumor | 2012 |
Enhancement of anthracycline and alkylator cytotoxicity by ethacrynic acid in primary cultures of human tissues.
Topics: Cell Survival; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Ethacrynic Acid; Human | 1990 |
Experience with thyroid malignancy in a private referral laboratory.
Topics: Adenoma; Adolescent; Adult; Aged; Carcinoma; Child; Ethacrynic Acid; Female; Humans; Iodine; Iodine | 1969 |