ethacrynic acid has been researched along with Liver Cirrhosis in 73 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Excerpt | Relevance | Reference |
---|---|---|
"5 cirrhotic patients with latent distal renal tubular acidosis (RTA) and 5 cirrhotic patients with normal distal acidification ability were studied." | 1.27 | Pathogenetic relationships between renal tubular acidosis and sodium metabolism alterations in liver cirrhosis. ( Caregaro, L; Gatta, A; Lauro, S; Ricci, G; Ruol, A; Zuin, R, 1983) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 73 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
CANNON, PJ | 2 |
AMES, RP | 1 |
LARAGH, JH | 4 |
LEDINGHAM, JG | 2 |
SPERBER, RJ | 1 |
DIRE, LB | 1 |
SINGER, MM | 1 |
FISCH, S | 1 |
DEGRAFF, AC | 1 |
HEINEMANN, HO | 1 |
STASON, WB | 1 |
RASMUSSEN, K | 1 |
MAHER, JF | 1 |
SCHREINER, GE | 1 |
BJORNEBOE, M | 1 |
Gómez Mont, F | 1 |
Landa, L | 1 |
Ramírez, C | 1 |
Perches, A | 1 |
Varay, A | 1 |
Castel, A | 1 |
Rain, JD | 1 |
de Sousa, RC | 1 |
Jenny, M | 1 |
Bufalari, A | 1 |
Meloni, G | 1 |
Caregaro, L | 1 |
Lauro, S | 1 |
Ricci, G | 1 |
Gatta, A | 1 |
Zuin, R | 1 |
Ruol, A | 1 |
Davies, IB | 1 |
Lightman, SL | 1 |
Mauro, G | 1 |
Cantino, G | 1 |
Vigiani, L | 1 |
Marra, N | 1 |
Micheli, E | 1 |
Spagnolo, G | 1 |
Werning, C | 1 |
Ruffo, A | 1 |
Motta, G | 1 |
Coltorti, M | 1 |
Radaeli, E | 1 |
Ciaccio, S | 1 |
Corsini, R | 1 |
Trebbi, R | 1 |
Sherlock, S | 3 |
Senewiratne, B | 3 |
Scott, A | 2 |
Walker, JG | 3 |
Roux, M | 1 |
Herne, N | 1 |
Gilly, R | 1 |
Michaud, J | 1 |
Le Gall, F | 1 |
Barjon, P | 2 |
Pelissier, JG | 1 |
Laroche, C | 1 |
Grégoire, J | 1 |
Fourcade, J | 1 |
Mimran, A | 1 |
Havard, CW | 1 |
Kofune, Y | 1 |
Honda, N | 1 |
Leemhuis, MP | 1 |
Struyvenberg, A | 1 |
Dzúriková, V | 1 |
Simoncic, E | 1 |
Laurincová, K | 1 |
Dzúrik, R | 1 |
Sidorenko, BA | 2 |
Kharchenko, VI | 2 |
Titov, VN | 1 |
Lotova, EV | 1 |
Mel'nichenko, GA | 2 |
Farel, H | 1 |
Fritel, D | 1 |
Milliez, P | 1 |
Richter, R | 1 |
Hartai, A | 1 |
Kirkendall, WM | 1 |
Stein, JH | 1 |
Imler, M | 1 |
Bockel, R | 1 |
Peter, B | 1 |
Kieny, R | 1 |
Stahl, J | 1 |
Jaros, Z | 1 |
Leiter, L | 1 |
Radó, JP | 1 |
Marosi, J | 1 |
Takó, J | 1 |
Perez-Stable, EC | 1 |
Materson, BJ | 1 |
Jahrmärker, H | 1 |
Anderton, JL | 1 |
Kincaid-Smith, P | 1 |
Tolstykh, AN | 1 |
Hwang, YS | 1 |
Mattar, E | 1 |
Cruz, HM | 1 |
Cruz, J | 1 |
de Almeida, AL | 1 |
Cardoso, TJ | 1 |
Rosenbojn, J | 1 |
Laudana, AA | 1 |
Lieberman, FL | 2 |
Reynolds, TB | 3 |
Balduini, M | 2 |
Amidani, A | 2 |
Scotti, G | 1 |
Gatti, A | 1 |
Sterz, H | 1 |
Earley, LE | 1 |
Martino, JA | 1 |
Cicconetti, C | 2 |
Cantera, N | 2 |
Yamada, S | 1 |
Bardi, A | 2 |
Merino, I | 2 |
Generini, G | 2 |
Rendic, Y | 2 |
Plaza de los Reyes, M | 1 |
Olmer, M | 1 |
Teule, M | 1 |
Bull, MB | 1 |
Zucchelli, P | 1 |
Petrella, A | 1 |
Fusaroli, M | 1 |
Sasdelli, M | 1 |
Melica, A | 1 |
Wallnöfer, H | 1 |
Hanusch, M | 1 |
Manghani, KK | 1 |
Patel, DG | 1 |
Doshi, JC | 1 |
Mehta, JM | 1 |
Sheth, UK | 1 |
Chodakowska, J | 1 |
Filipecki, S | 1 |
Koçak, N | 1 |
Ozdoğan, E | 1 |
Warembourg, H | 1 |
Bertrand, M | 1 |
Robert, M | 1 |
Portmann, B | 1 |
Andrieu, J | 1 |
Lesueur, G | 1 |
Iványi, J | 1 |
Matz, GJ | 1 |
Beal, DD | 1 |
Krames, L | 1 |
Steigmann, F | 1 |
Mejicano, R | 1 |
Bayliss, RI | 1 |
Wayne, HH | 1 |
Kotler, SA | 1 |
McGirr, PS | 1 |
Stoike, RD | 1 |
Doyle, AE | 1 |
Ekert, H | 1 |
Trevaks, G | 1 |
8 reviews available for ethacrynic acid and Liver Cirrhosis
Article | Year |
---|---|
Refractory oedema.
Topics: Aminophylline; Bumetanide; Diuretics; Drug Therapy, Combination; Edema; Edema, Cardiac; Ethacrynic A | 1980 |
Significance of hypokalaemia due to diuretics.
Topics: Amiloride; Arrhythmias, Cardiac; Chlorothiazide; Diuretics; Ethacrynic Acid; Extracellular Space; Fu | 1973 |
Clinical pharmacology of furosemide and ethacrynic acid.
Topics: Anuria; Diabetes Insipidus; Edema; Ethacrynic Acid; Furosemide; Heart Failure; Hemodynamics; Humans; | 1968 |
[Edecrin].
Topics: Animals; Chickens; Diuresis; Ethacrynic Acid; Exercise Test; Glucose; Heart Failure; Humans; Liver C | 1970 |
Combinations of diuretics in the treatment of edema.
Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu | 1970 |
Diuretic drug therapy of edema.
Topics: Ambulatory Care; Ascites; Body Weight; Chlorides; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furos | 1971 |
[When and which diuretics? General and specific indications for diuretic therapy].
Topics: Acid-Base Equilibrium; Brain Edema; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; | 1971 |
Diuretics. II. Clinical considerations.
Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I | 1971 |
6 trials available for ethacrynic acid and Liver Cirrhosis
Article | Year |
---|---|
[Use of ethacrynic acid in the teatment of edematous states].
Topics: Clinical Trials as Topic; Drug Evaluation; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirr | 1973 |
[Clinical study of a new diuretic: ethacrynic acid (M.K. 595)].
Topics: Adult; Aged; Clinical Trials as Topic; Ethacrynic Acid; Female; Heart Failure; Humans; Hypertension; | 1965 |
[Clinical and experimental studies of a new diuretic: ethacrynic acid].
Topics: Clinical Trials as Topic; Ethacrynic Acid; Heart Diseases; Humans; Liver Cirrhosis | 1967 |
High doses of spironolactone (Aldactone, SC-14266, Verospirone) alone and in combination with triamterene and-or diuretics in the treatment of refractory edema associated with secondary hyperaldosteronism.
Topics: Adult; Aged; Body Weight; Chlorides; Clinical Trials as Topic; Clopamide; Creatinine; Diet, Sodium-R | 1970 |
The use of ethacrynic acid in patients with cirrhosis and ascites.
Topics: Alkalosis; Ascites; Clinical Trials as Topic; Ethacrynic Acid; Humans; Hypokalemia; Liver Cirrhosis | 1965 |
Amiloride (MK-870), a new antikaluretic diuretic. Comparison to other antikaluretic diuretics in patients with liver disease and ascites.
Topics: Acid-Base Equilibrium; Amidines; Ascites; Autopsy; Carcinoma; Diuretics; Ethacrynic Acid; Humans; Hy | 1970 |
59 other studies available for ethacrynic acid and Liver Cirrhosis
Article | Year |
---|---|
METHYLENEBUTYRYL PHENOXYACETIC ACID: NOVEL AND POTENT NATRIURETIC AND DIURETIC AGENT.
Topics: Acetates; Diuretics; Ethacrynic Acid; Heart Failure; Humans; Kidney Function Tests; Liver Cirrhosis; | 1963 |
ETHACRYNIC ACID PARENTERALLY IN THE TREATMENT AND PREVENTION OF PULMONARY OEDEMA.
Topics: Adrenalectomy; Ascites; Blood Transfusion; Chlorothiazide; Digoxin; Diuretics; Edema; Ethacrynic Aci | 1964 |
ETHACRYNIC ACID IN PATHOLOGICAL FLUID RETENTION.
Topics: Digoxin; Diuretics; Drug Therapy; Ethacrynic Acid; Geriatrics; Heart Failure; Humans; Hydrochlorothi | 1965 |
ETHACRYNIC ACID: EFFECTIVENESS AND MODE OF DIURETIC ACTION IN MAN.
Topics: Acetazolamide; Acidosis; Acidosis, Renal Tubular; Alkalosis; Ascites; Carbonic Anhydrase Inhibitors; | 1965 |
[ETHACRYNIC ACID. CLINICAL EXPERIENCES WITH A NEW ORAL DIURETIC].
Topics: Diuretics; Drug Therapy; Edema; Ethacrynic Acid; Geriatrics; Heart Failure; Humans; Liver Cirrhosis; | 1964 |
STUDIES ON ETHACRYNIC ACID IN PATIENTS WITH REFRACTORY EDEMA.
Topics: Alkalosis; Blood; Chlorides; Creatine; Creatinine; Diuretics; Drug Therapy; Edema; Ethacrynic Acid; | 1965 |
[DRUG TREATMENT OF LIVER CIRRHOSIS].
Topics: Diuretics; Drug Therapy; Ethacrynic Acid; Furosemide; Humans; Liver Cirrhosis; Triamterene | 1965 |
[Management of ascites in the cirrhotic patient using a 6-chloro-pyrazinamine derivative. I. Metabolic studies].
Topics: Ascites; Diuresis; Ethacrynic Acid; Humans; Liver Cirrhosis; Pyrazinamide; Spironolactone | 1966 |
[Use of ethacrynic acid and the ethacrynic acid - spirolactone combination in cirrhosis and the icterus of cirrhosis].
Topics: Ethacrynic Acid; Humans; Jaundice; Liver Cirrhosis; Spironolactone | 1967 |
Clinical study of a new diuretic--ethacrynic acid.
Topics: Alkalosis; Ascites; Blood; Body Weight; Chlorides; Edema; Ethacrynic Acid; Heart Failure; Humans; Li | 1967 |
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal | 1967 |
Pathogenetic relationships between renal tubular acidosis and sodium metabolism alterations in liver cirrhosis.
Topics: Acidosis, Renal Tubular; Adult; Ethacrynic Acid; Female; Humans; Hydrogen-Ion Concentration; Kidney | 1983 |
[Clinical evaluation of bumetanide in the diuretic treatment of heart failure and liver cirrhosis].
Topics: Adult; Aged; Bumetanide; Diuresis; Diuretics; Electrolytes; Ethacrynic Acid; Female; Furosemide; Hea | 1981 |
[Controlled clinical study of the effect of combined administration of ethacrynic acid and spironolactone in ascitic liver cirrhosis].
Topics: Ascites; Drug Evaluation; Drug Synergism; Ethacrynic Acid; Humans; Liver Cirrhosis; Spironolactone | 1979 |
[The therapy of edematous diseases].
Topics: Antihypertensive Agents; Bed Rest; Diabetes Insipidus; Diuretics; Diuretics, Osmotic; Edema; Ethacry | 1977 |
[Criteria for intensive treatment of hepatic coma].
Topics: Adult; Aged; Animals; Cholangitis; Ethacrynic Acid; Extracorporeal Circulation; Female; Furosemide; | 1976 |
[Therapeutic report on an injectable aldosterone antagonist (K-canrenoate) in states of water-salf retention].
Topics: Adult; Aged; Ascites; Canrenoic Acid; Drug Evaluation; Drug Therapy, Combination; Edema; Ethacrynic | 1976 |
Complications of diuretic therapy in hepatic cirrhosis.
Topics: Chlorothiazide; Diuretics; Ethacrynic Acid; Furosemide; Hepatic Encephalopathy; Humans; Hypokalemia; | 1966 |
Amiloride ('MK 870') in patients with ascites due to cirrhosis of the liver.
Topics: Adult; Ascites; Bicarbonates; Creatinine; Diuretics; Ethacrynic Acid; Furosemide; Guanidines; Humans | 1968 |
[Clinical study of amiloride hydrochloride, a diuretic with low potassium loss].
Topics: Arrhythmias, Cardiac; Blood Urea Nitrogen; Cardiac Complexes, Premature; Diuretics; Drug Synergism; | 1970 |
[The treatment of hydropigenous syndromes with ethacrynic acid. (Apropos of 100 cases)].
Topics: Adult; Aged; Diuretics; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirrhosis; Middle Aged; | 1967 |
[Clinical trials of ethacrynic acid].
Topics: Adult; Ascites; Edema; Ethacrynic Acid; Female; Heart Failure; Humans; Liver Cirrhosis; Male; Middle | 1967 |
[Transient deafness and ethacrynic acid. Possible role of the changes in the composition of cochlear fluids].
Topics: Action Potentials; Ascites; Cochlea; Deafness; Ethacrynic Acid; Female; Humans; Hypokalemia; Labyrin | 1972 |
Diuretics.
Topics: Benzothiadiazines; Blood; Chlorides; Diuretics; Diuretics, Osmotic; Edema; Ethacrynic Acid; Heart Di | 1974 |
[Liver cirrhosis].
Topics: Ascites; Diuretics; Ethacrynic Acid; Humans; Liver Cirrhosis | 1974 |
[Comparison of the effectiveness and mechanism of action of the saluretic preparations triamterene and hypothiazide and their combination (triampur) in circulatory insufficiency].
Topics: Acid-Base Equilibrium; Adult; Aged; Arteriosclerosis; Circadian Rhythm; Coronary Disease; Creatinine | 1973 |
[Importance of hyperammoniemia of the renal origin in the pathogenesis of hepatic coma released in cirrhotic patients by diuretics generating hypokaliemia].
Topics: Acetazolamide; Acid-Base Equilibrium; Alkalosis; Ammonia; Ascites; Chlorides; Chlorthalidone; Edema; | 1969 |
[Comparison of the effectiveness and mechanism of action of the saluretics lasix, ethacrynic acid, brinaldix and triamterene in congestive cardiac insufficiency].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Coronary Disease; Diuretics; Ethacrynic Acid; Female; Fur | 1971 |
The complications of diuretic therapy in patients with cirrhosis.
Topics: Alkalosis; Ascites; Blood Urea Nitrogen; Chlorothiazide; Ethacrynic Acid; Furosemide; Hepatic Enceph | 1966 |
[The diuretic activity of ethacrynic acid].
Topics: Adolescent; Adult; Diabetic Nephropathies; Diuresis; Electrocardiography; Ethacrynic Acid; Female; H | 1969 |
[Immediate effects of a new diuretic-ethacrynic acid (MK-595)-on the metabolism of sodium, chloride, potassium and water in edematous conditions].
Topics: Chlorides; Diuresis; Ethacrynic Acid; Female; Heart Failure; Humans; Liver Cirrhosis; Male; Middle A | 1965 |
[Clinical evaluation of the diuretic effect of ethacrynic acid].
Topics: Aged; Diuresis; Edema; Ethacrynic Acid; Heart Failure; Humans; Kidney; Liver Cirrhosis; Male; Middle | 1969 |
[Ethacrynic acid in the therapy of edematogenic syndromes resistant to other diuretics in senile subjects].
Topics: Cardiovascular Diseases; Diuresis; Edema; Electrolytes; Ethacrynic Acid; Humans; Hyperthyroidism; Ki | 1969 |
[Clinical studies on the diuretic effect of ethacrynic acid].
Topics: Diabetes Complications; Diuresis; Edema; Electrolytes; Ethacrynic Acid; Heart Failure; Humans; Hypon | 1969 |
Influence of sodium balance on the ability of diuretics to inhibit tubular reabsorption. A study of factors that influence renal tubular sodium reabsorption in man.
Topics: Adult; Ascites; Chlorothiazide; Ethacrynic Acid; Female; Glomerular Filtration Rate; Humans; Kidney | 1970 |
[Preliminary clinical trials of ethacrynic acid in intravenous administration].
Topics: Adult; Aged; Ascites; Cardiovascular Diseases; Diuretics; Edema; Ethacrynic Acid; Female; Heart Fail | 1970 |
[Effect of ethacrynic acid on diuresis, salidiuresis and electrolyte concentration of the plasma in liver cirrhosis patients with ascites].
Topics: Diuresis; Electrolytes; Ethacrynic Acid; Humans; Liver Cirrhosis | 1967 |
[Results and therapeutic indications of a new diuretic: ethacrynic acid].
Topics: Ascites; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirrhosis | 1967 |
Amiloride. A potassium-sparing natriuretic agent.
Topics: Acetazolamide; Aldosterone; Ammonia; Ascites; Bicarbonates; Blood Pressure; Chlorides; Chlorothiazid | 1968 |
[Ethacrynic acid: research on the mechanism of action and clinical use].
Topics: Adolescent; Adult; Aged; Child; Diabetes Insipidus; Diuresis; Edema; Ethacrynic Acid; Female; Heart | 1968 |
Ethacrynic acid and furosemide.
Topics: Ethacrynic Acid; Furosemide; Heart Failure; Humans; Liver Cirrhosis; Nephrosis | 1968 |
[Diuresis with edecrin].
Topics: Adult; Aged; Diabetes Mellitus; Diuretics; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirr | 1968 |
Comparative potency study of ethacrynic acid and mersalyl as diuretics in hepatic cirrhosis.
Topics: Ethacrynic Acid; Humans; Liver Cirrhosis; Male; Organomercury Compounds; Potassium; Sodium | 1968 |
Ethacrynic acid in patients with salt and water retention-a clinical appraisal.
Topics: Chlorides; Edema; Ethacrynic Acid; Heart Failure; Humans; Hypernatremia; Hyponatremia; Kidney Failur | 1968 |
[Urinary excretion of magnesium in patients with liver cirrhosis treated with oral diuretics. Its variation through vasopressin].
Topics: Adult; Ascites; Diuretics; Ethacrynic Acid; Furosemide; Humans; Liver Cirrhosis; Magnesium; Male; Th | 1968 |
[Effect of ethacrynic acid on diuresis, electrolyte excretion, and renal function in cases of liver cirrhosis].
Topics: Diuresis; Electrolytes; Ethacrynic Acid; Female; Glomerular Filtration Rate; Humans; Kidney Function | 1968 |
[Clinical evaluation of the diuretic effect of ethacrynic acid].
Topics: Aged; Diuresis; Edema; Ethacrynic Acid; Heart Failure; Humans; Kidney; Liver Cirrhosis; Male; Middle | 1968 |
[Clinical study of a new diuretic: ethacrynic acid].
Topics: Adult; Aged; Diuresis; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirrhosis; Metabolic Cle | 1968 |
[Clinical experience with the use of a new drug: "ethacrynic acid"].
Topics: Adult; Aged; Ascites; Diuresis; Edema; Electrolytes; Ethacrynic Acid; Female; Heart Failure; Humans; | 1969 |
[Influence of diuretics on the survival of 180 patients with cirrhosis of the liver and ascites].
Topics: Adult; Aged; Alcoholism; Ascites; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Humans | 1969 |
[Diuretics in cirrhosis. Accidents. Indications].
Topics: Adrenal Cortex Hormones; Alkalosis; Blood Urea Nitrogen; Blood Volume; Diuretics; Edema; Ethacrynic | 1969 |
[Experiences with ethacrynic acid (Edecrin)].
Topics: Cardiovascular Diseases; Diuretics; Edema; Ethacrynic Acid; Extremities; Humans; Liver Cirrhosis; Ne | 1969 |
Ototoxicity of ethacrynic acid. Demonstrated in a human temporal bone.
Topics: Acute Kidney Injury; Deafness; Ear, Inner; Ear, Middle; Ethacrynic Acid; Female; Humans; Liver Cirrh | 1969 |
The impact of diuretics on chronic liver disease.
Topics: Alcoholism; Ascites; Chlorothiazide; Diet Therapy; Diuretics; Ethacrynic Acid; Furosemide; Humans; L | 1969 |
Ethacrynic acid: two years' experience with a new diuretic.
Topics: Benzothiadiazines; Blood; Edema; Ethacrynic Acid; Heart Failure; Liver Cirrhosis; Nephrotic Syndrome | 1965 |
Ethacrynic acid. Use in ambulatory patients with resistant edema.
Topics: Adolescent; Adult; Aged; Blood; Chlorides; Edema; Electrolytes; Ethacrynic Acid; Female; Heart Failu | 1965 |
Ethacrynic acid in the treatment of patients resistant to thiazides.
Topics: Diuretics; Edema; Ethacrynic Acid; Heart Failure; Humans; Liver Cirrhosis; Nephrotic Syndrome | 1966 |
Fatal agranulocytosis complicating treatment with ethacrynic acid. Report of a case.
Topics: Agranulocytosis; Ethacrynic Acid; Female; Humans; Liver Cirrhosis; Middle Aged | 1966 |
Renal failure with cirrhosis. Observations on the role of diuretics.
Topics: Acute Kidney Injury; Aminohippuric Acids; Ascites; Blood; Blood Volume; Creatine; Diuretics; Ethacry | 1966 |