Page last updated: 2024-10-26

ethacrynic acid and Leukemia, Myeloid, Acute

ethacrynic acid has been researched along with Leukemia, Myeloid, Acute in 2 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Twentyman, PR1
Lambert, E1
Müller, M1
Rees, JK1
Handa, SP1

Other Studies

2 other studies available for ethacrynic acid and Leukemia, Myeloid, Acute

ArticleYear
Selective toxicity of ethacrynic acid towards lymphocytes of chronic lymphocytic leukemia in vitro.
    Leukemia, 1992, Volume: 6, Issue:7

    Topics: Cell Survival; Dose-Response Relationship, Drug; Ethacrynic Acid; Humans; In Vitro Techniques; Leuke

1992
Acute renal railure in association with hyperuricemia: its recovery with ethacrynic acid.
    Southern medical journal, 1971, Volume: 64, Issue:6

    Topics: Acute Kidney Injury; Bicarbonates; Ethacrynic Acid; Female; Humans; Infusions, Parenteral; Leukemia,

1971