ethacrynic acid has been researched along with Labyrinth Diseases in 13 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Labyrinth Diseases: Pathological processes of the inner ear (LABYRINTH) which contains the essential apparatus of hearing (COCHLEA) and balance (SEMICIRCULAR CANALS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "1." | 1.26 | Experimental pathogenesis of hydrops. ( Kimura, RS, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kashio, A | 1 |
| Sakamoto, T | 1 |
| Kakigi, A | 1 |
| Suzuki, M | 1 |
| Suzukawa, K | 1 |
| Kondo, K | 1 |
| Sato, Y | 1 |
| Asoh, S | 1 |
| Ohta, S | 1 |
| Yamasoba, T | 1 |
| Lerner, SA | 1 |
| Matz, GJ | 1 |
| Hybels, RL | 1 |
| Tiedemann, R | 1 |
| Marlowe, FI | 1 |
| Kasajima, K | 1 |
| Kaneko, Y | 1 |
| Ouchi, J | 1 |
| Bosher, SK | 1 |
| Kimura, RS | 1 |
| Hommerich, CP | 1 |
| Paparella, MM | 1 |
| Silverstein, H | 1 |
| Begin, R | 1 |
| Johnsson, LG | 1 |
| Hawkins, JE | 1 |
| Federspil, P | 1 |
1 review available for ethacrynic acid and Labyrinth Diseases
| Article | Year |
|---|---|
Ototoxicity of loop diuretics. Morphological and electrophysiological examinations in animal experiments.
Topics: Animals; Cochlea; Columbidae; Diuretics; Ear, Inner; Ethacrynic Acid; Guinea Pigs; Hair Cells, Audit | 1990 |
12 other studies available for ethacrynic acid and Labyrinth Diseases
| Article | Year |
|---|---|
Topical application of the antiapoptotic TAT-FNK protein prevents aminoglycoside-induced ototoxicity.
Topics: Administration, Topical; Aminoglycosides; Animals; Apoptosis; Caspase 9; Cochlea; Ethacrynic Acid; E | 2012 |
Aminoglycoside ototoxicity.
Topics: Adult; Aminoglycosides; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Ethac | 1980 |
Drug toxicity of the inner ear.
Topics: Animals; Chloroquine; Dihydrostreptomycin Sulfate; Ethacrynic Acid; Furosemide; Gentamicins; Humans; | 1979 |
[The conservative treatment of inner ear diseases. A survey of the actual possibilities (author's transl)].
Topics: Anti-Bacterial Agents; Deafness; Diuretics; Edema; Ethacrynic Acid; Hair Cells, Auditory; Hearing Di | 1978 |
Ototoxic agents.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Aspirin; Child; Drug-Related Side Effects and Adver | 1978 |
Changes of the stria vascularis induced by ethacrynic acid.
Topics: Animals; Capillaries; Capillary Permeability; Cochlea; Ethacrynic Acid; Guinea Pigs; Labyrinth Disea | 1978 |
Ethacrynic acid ototoxicity as a general model in cochlear pathology.
Topics: Action Potentials; Animals; Cell Membrane Permeability; Cochlea; Disease Models, Animal; Endolymph; | 1977 |
Experimental pathogenesis of hydrops.
Topics: Animals; Cochlea; Constriction, Pathologic; Ear, Inner; Edema; Endolymph; Ethacrynic Acid; Guinea Pi | 1976 |
The dizzy patient.
Topics: Diazepam; Drainage; Ear; Ear Neoplasms; Ethacrynic Acid; Gentamicins; Hearing Disorders; Humans; Inf | 1972 |
Ethacrynic acid--its reversible ototoxicity.
Topics: Anesthesia, Inhalation; Animals; Cats; Cochlea; Dose-Response Relationship, Drug; Electrophysiology; | 1974 |
Strial atrophy in clinical and experimental deafness.
Topics: Animals; Atrophy; Basement Membrane; Blood Vessels; Cochlea; Deafness; Dogs; Ethacrynic Acid; Gentam | 1972 |
[Review of observed gentamicin ototoxicity cases in Germany].
Topics: Adolescent; Adult; Aged; Diabetes Complications; Drug Synergism; Ethacrynic Acid; Gentamicins; Germa | 1971 |