ethacrynic acid has been researched along with Kidney, Polycystic in 1 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrocortisone acetate is known to produce polycystic kidney disease when administered to susceptible animals in the perinatal period." | 1.27 | Effects of lithium chloride and ethacrynic acid on experimental polycystic kidney disease. ( Crocker, JF; McDonald, AT, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crocker, JF | 1 |
| McDonald, AT | 1 |
1 other study available for ethacrynic acid and Kidney, Polycystic
| Article | Year |
|---|---|
Effects of lithium chloride and ethacrynic acid on experimental polycystic kidney disease.
Topics: Animals; Biological Transport; Blood; Chlorides; Ethacrynic Acid; Female; Histocytochemistry; Hydroc | 1988 |