ethacrynic acid has been researched along with Ischemia in 16 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ampullar endolymphatic potential (AEP) was studied in the guinea pig during ischemia and asphyxia and following systemic application of ethacrynic acid." | 3.65 | Effects of anoxia and ethacrynic acid upon ampullar endolymphatic potential and upon high energy phosphates in ampullar wall. ( Kusakari, J; Thalmann, R, 1976) |
| "The effect of dehydration on intrarenal blood flow was investigated in 11 dogs, using polarographic determination of H2-gas desaturation for measuring local blood flow in inner cortex (ICF) and outer cortex (OCF)." | 1.26 | Effect of dehydration on renal blood flow in dog. ( Kirkebo, A; Tyssebotn, I, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, D | 1 |
| McFadden, SL | 1 |
| Woo, JM | 1 |
| Salvi, RJ | 1 |
| Chen, XM | 2 |
| Ahlström, P | 1 |
| Thalmann, I | 1 |
| Thalmann, R | 3 |
| Ise, I | 1 |
| Arfors, KE | 1 |
| Tuma, RF | 1 |
| Agerup, B | 1 |
| Kirkebo, A | 1 |
| Tyssebotn, I | 1 |
| Lebedev, AA | 1 |
| Dubishchev, AV | 1 |
| Kusakari, J | 2 |
| Din, DL | 1 |
| Luo, DF | 1 |
| Huangfu, MS | 1 |
| Jin, XM | 1 |
| Mori, N | 1 |
| Ninoyu, O | 1 |
| Morgenstern, C | 1 |
| Song, SY | 1 |
| Scheuer, J | 1 |
| Miyoshi, T | 1 |
| Le Gall, JR | 1 |
| Gajdos, P | 1 |
| Eng, K | 1 |
| Stahl, WM | 1 |
| Nanninga, JB | 2 |
| Holland, JM | 2 |
| Grayhack, JT | 2 |
| Deam, M | 1 |
1 review available for ethacrynic acid and Ischemia
| Article | Year |
|---|---|
[Present data on the physiopathology of acute kidney tubule diseases].
Topics: Acute Disease; Acute Kidney Injury; Animals; Dogs; Ethacrynic Acid; Glomerular Filtration Rate; Hemo | 1971 |
15 other studies available for ethacrynic acid and Ischemia
| Article | Year |
|---|---|
Ethacrynic acid rapidly and selectively abolishes blood flow in vessels supplying the lateral wall of the cochlea.
Topics: Action Potentials; Animals; Arterioles; Chinchilla; Cochlea; Cochlear Microphonic Potentials; Diuret | 2002 |
[Experimental study on the therapeutic value of microwave on hearing loss due to ethacrynic acid ototoxicity].
Topics: Animals; Auditory Threshold; Cochlear Duct; Ethacrynic Acid; Evoked Potentials, Auditory, Brain Stem | 1993 |
Cyclic AMP and adenylate cyclase in the inner ear.
Topics: Action Potentials; Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Barbiturates; Brain; Bucla | 1975 |
Biospheres--a tool to induce transient ischemia in experimental medicine as studied in the kidney.
Topics: Amylases; Animals; Blood Flow Velocity; Dogs; Ethacrynic Acid; Ischemia; Kidney; Microspheres; Renal | 1979 |
Effect of dehydration on renal blood flow in dog.
Topics: Animals; Dehydration; Dogs; Ethacrynic Acid; Ischemia; Kidney Cortex; Peritoneal Dialysis; Regional | 1977 |
[Kidney function and mitochondrial metabolism in excluded renal blood flow against a background of diuretic action].
Topics: Animals; Diuretics; Drug Combinations; Ethacrynic Acid; Female; Furosemide; Ischemia; Kidney; Kidney | 1978 |
Effects of anoxia and ethacrynic acid upon ampullar endolymphatic potential and upon high energy phosphates in ampullar wall.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Ear, Inner; Energy Metabolism; Ethacrynic Acid; | 1976 |
[Deafness, induced by sodium ethacrynate in guinea pigs, alleviated by microwave treatment].
Topics: Animals; Cochlea; Disease Models, Animal; Ethacrynic Acid; Guinea Pigs; Hearing Loss, Conductive; Is | 1992 |
Cation transport in the ampulla of the semicircular canal and in the endolymphatic sac.
Topics: Animals; Biological Transport; Ear, Inner; Electrophysiology; Endolymphatic Sac; Ethacrynic Acid; Gu | 1987 |
The effects of pharmacologic agents on myocardial sodium (Na+) and potassium (K+) stimulated ATPase.
Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Chlorothiazide; Dogs; Ethacrynic A | 1968 |
Dysfunctions of energy releasing and consuming processes of the cochlea.
Topics: Adenosine Triphosphate; Animals; Asphyxia; Brain; Cochlea; Ear; Ear, Inner; Energy Metabolism; Ethac | 1973 |
[Current physiopathological data on the precocious treatment of acute tubular diseases by furosemide or high doses of ethacrynic acid].
Topics: Acute Kidney Injury; Ethacrynic Acid; Furosemide; Ischemia; Kidney; Kidney Cortex Necrosis; Kidney G | 1972 |
Correction of the renal hemodynamic changes produced by surgical trauma.
Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Dogs; Ethacrynic Acid; Extracorporeal Circulation | 1971 |
Metabolic inhibitors and renal ischemia.
Topics: Animals; Antimetabolites; Creatinine; Cyanides; Ethacrynic Acid; Furosemide; Ischemia; Kidney; Magne | 1971 |
Adjuncts to renal preservation.
Topics: Animals; Creatinine; Cyanides; Ethacrynic Acid; Furosemide; Glucose; Hexoses; Hydrocortisone; Insuli | 1969 |