ethacrynic acid has been researched along with Inappropriate ADH Syndrome in 2 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Decaux, G | 1 |
| Abramow, M | 1 |
| Dratwa, M | 1 |
| Cogan, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Urea for Chronic Hyponatremia: A Pilot Study[NCT04588207] | Phase 2 | 2 participants (Actual) | Interventional | 2021-12-28 | Terminated (stopped due to Unable to recruit participants) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for ethacrynic acid and Inappropriate ADH Syndrome
| Article | Year |
|---|---|
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone by long loop diuretics.
Topics: Adolescent; Aged; Diuresis; Ethacrynic Acid; Female; Furosemide; Humans; Inappropriate ADH Syndrome; | 1983 |
Furosemide in inappropriate secretion of antidiuretic hormone.
Topics: Ethacrynic Acid; Furosemide; Humans; Inappropriate ADH Syndrome; Kidney Tubules | 1981 |